Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Roy G. Goldie"'
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 1 (2007)
Asthma is a complex inflammatory disease of the airways involving reversible bronchoconstriction. Chronic obstructive pulmonary disease is typified by inflammation and airflow limitation that has an irreversible component. There is now substantial ev
Externí odkaz:
https://doaj.org/article/122351648e0d468fabd1cf5345ea9c55
Publikováno v:
Proinflammatory and Antiinflammatory Peptides ISBN: 9781003064695
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::310c9dd904cfe0b1da1dd6e0320d8f68
https://doi.org/10.1201/9781003064695-10
https://doi.org/10.1201/9781003064695-10
Autor:
Janet M.H. Preuss, Roy G. Goldie
Publikováno v:
AIRWAY WALL REMODELLING in ASTHMA ISBN: 9781003068792
AIRWAY WALL REMODELLING in ASTHMA
AIRWAY WALL REMODELLING in ASTHMA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05ad3e2c2ed0d9ba4cd228832d1cda3d
https://doi.org/10.1201/9781003068792-5
https://doi.org/10.1201/9781003068792-5
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 1 (2007)
Asthma is a complex inflammatory disease of the airways involving reversible bronchoconstriction. Chronic obstructive pulmonary disease is typified by inflammation and airflow limitation that has an irreversible component. There is now substantial ev
Autor:
Roy G. Goldie, Angela C. D'Aprile, Glenn J. Self, Peter J. Henry, Tracey Sew, Lynette B. Fernandes, Melanie McGuire
Publikováno v:
European Journal of Pharmacology. 550:155-161
This study examined the effects of the selective Rho-kinase inhibitor Y-27632 [(+)-(R)-trans-4-(1-aminoethyl)-(4-pyridyl)cyclohexanecarboxamide dihydrochloride]) on cholinergic nerve-mediated contraction and neurotransmitter release in murine and gui
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 18:67-74
Asthma is a complex inflammatory disorder involving obstruction, constriction, oedema, remodelling and hyperresponsiveness of the airways. These effects are induced by a raft of mediators, many of which exert their actions by stimulating specific G-p
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 283:L1072-L1078
Within the airways, endothelin-1 (ET-1) can exert a range of prominent effects, including airway smooth muscle contraction, bronchial obstruction, airway wall edema, and airway remodeling. ET-1 also possesses proinflammatory properties and contribute
Publikováno v:
Clinical Science. 103:345S-348S
We examined the impact of parainfluenza-3 (P-3) respiratory tract viral infection on the density and function of endothelin (ET) receptor subtypes (ETA and ETB) in guinea pig tracheal smooth muscle. Total specific binding of [125I]ET-1 and the relati
Publikováno v:
Clinical Science. 103:353S-356S
The present study examined the roles of endothelin-converting enzyme (ECE), neutral endopeptidase (NEP) and mast cell chymase as processors of the endothelin (ET) analogues ET-1(1-21), ET-1(1-31) and big ET-1 in the trachea of allergic mice. Male CBA
Autor:
Douglas W. P. Hay, Paul Rigby, Rodney M Moesker, Roy G. Goldie, Mark A. Luttmann, Glenn J. Self, Zhaohui Ao, Stephen A. Douglas
Publikováno v:
British Journal of Pharmacology. 132:1905-1915
The role of endothelin B (ETB) receptors in mediating ET ligand-induced contractions in mouse trachea was examined in ETB receptor knockout animals. Autoradiographic binding studies, using [125I]-ET-1, confirmed the presence of ETA receptors in trach