Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Roy Fox"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Niclosamide and benzbromarone have been described as inhibitors of the calcium activated chloride channel, TMEM16A, and on this basis have been considered and tested as clinical candidates for the treatment of airway diseases. However, both compounds
Externí odkaz:
https://doaj.org/article/f8497bc692b84a53bb5f159ecd7524a9
Autor:
Henry Danahay, Roy Fox, Sarah Lilley, Holly Charlton, Kathryn Adley, Lee Christie, Ejaz Ansari, Camille Ehre, Alexis Flen, Michael J. Tuvim, Burton F. Dickey, Colin Williams, Sarah Beaudoin, Stephen P Collingwood, Martin Gosling
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 8, Pp 464-477 (2020)
Abstract The calcium‐activated chloride channel (CaCC) TMEM16A enables chloride secretion across several transporting epithelia, including in the airways. Additional roles for TMEM16A have been proposed, which include regulating mucus production an
Externí odkaz:
https://doaj.org/article/83ed811c2488412dac57b82211c99ada
Autor:
Meredith A. Ray, PhD, Nicholas R. Faris, M. Div., Carrie Fehnel, BBA, Anna Derrick, CTR, Matthew P. Smeltzer, PhD, Meghan B. Meadows-Taylor, PhD, Folabi Ariganjoye, M.B.B.S., Alicia Pacheco, MHA, Robert Optican, MD, FACR, Keith Tonkin, MD, Jeffrey Wright, MD, PhD, FCCP, Roy Fox, MD, Thomas Callahan, MD, Edward T. Robbins, MD, William Walsh, MD, Philip Lammers, MD, Shailesh Satpute, MD, PhD, Raymond U. Osarogiagbon, M.B.B.S.
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 8, Pp 100203- (2021)
Introduction: We compared NSCLC treatment and survival within and outside a multidisciplinary model of care from a large community health care system. Methods: We implemented a rigorously benchmarked “enhanced” Multidisciplinary Thoracic Oncology
Externí odkaz:
https://doaj.org/article/c8f7bc97096f4078b99730e43af6a700
Autor:
Mike Petrassi, Rob Barber, Celine Be, Sarah Beach, Brian Cox, Anne-Marie D’Souza, Nick Duggan, Martin Hussey, Roy Fox, Peter Hunt, Gabor Jarai, Takatoshi Kosaka, Paul Oakley, Viral Patel, Neil Press, David Rowlands, Clemens Scheufler, Oliver Schmidt, Honnappa Srinivas, Mary Turner, Rob Turner, John Westwick, Alison Wolfreys, Nuzhat Pathan, Simon Watson, Matthew Thomas
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Pulmonary arterial hypertension (PAH) has demonstrated multi-serotonin receptor dependent pathologies, characterized by increased tone (5-HT1B receptor) and complex lesions (SERT, 5-HT1B, 5-HT2B receptors) of the pulmonary vasculature together with r
Externí odkaz:
https://doaj.org/article/be575ec27b9d4ba3b8e400bbf8ceb145
Publikováno v:
Journal of Multidisciplinary Healthcare, Vol 2009, Iss default, Pp 53-59 (2009)
Tara Sampalli1, Elizabeth Berlasso1, Roy Fox1, Mark Petter21Nova Scotia Environmental Health Centre, Fall River, Nova Scotia, Canada; 2Doctoral Candidate, Department of Psychology, Dalhousie University, Halifax, CanadaBackground: The objective of thi
Externí odkaz:
https://doaj.org/article/d0bf46e8a2e24c7f88e89f7ffcdb7dfd
Publikováno v:
Journal of Multidisciplinary Healthcare, Vol 2008, Iss default, Pp 97-104 (2008)
Roy Fox1, Tara Sampalli1, Jonathan Fox11Nova Scotia Environmental Health Centre, Fall River, NS, CanadaAbstract: The Nova Scotia Environmental Health Centre is a treatment facility for individuals with chronic environmental conditions such as multipl
Externí odkaz:
https://doaj.org/article/3f8d87585d6042febdb746169406944c
Publikováno v:
International Journal of Integrated Care, Vol 10, Iss 1 (2010)
Objective: To determine the content coverage in SNOMED CT® to represent the multidisciplinary terms and concepts in the domain for complex chronic conditionsMethods: An evaluation of the coverage of multidisciplinary health factors in SNOMED CT® fo
Externí odkaz:
https://doaj.org/article/e3f0cb6efd834f2fafb8df69799b4a57
Autor:
Meghan B, Meadows-Taylor, Nicholas R, Faris, Matthew P, Smeltzer, Meredith A, Ray, Carrie, Fehnel, Olawale, Akinbobola, Folabi, Ariganjoye, Anita, Patel, Alicia, Pacheco, Anurag, Mehrotra, Roy, Fox, Robert, Optican, Keith, Tonkin, James, Machin, Jeffrey, Wright, Edward T, Robbins, Raymond U, Osarogiagbon
Publikováno v:
Chest. 162:242-255
Lung cancer management guidelines strive to improve outcomes. Theoretically, thorough staging promotes optimal treatment selection. We examined the association between guideline-concordant invasive mediastinal nodal staging, guideline-concordant trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9baf84bdc55533db2b3a25e27d42f8
https://doi.org/10.1016/j.chest.2022.01.046
https://doi.org/10.1016/j.chest.2022.01.046
Publikováno v:
Proceedings of the ACM on Programming Languages. 3:1-27
Developers nowadays have to contend with a growing number of APIs. While in the long-term they are very useful to developers, many modern APIs have an incredibly steep learning curve, due to their hundreds of functions handling many arguments, obscur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d2909cdf14af0cb7b0050db0dbdb68c
https://doi.org/10.1145/3360594
https://doi.org/10.1145/3360594
Autor:
Lee Christie, Holly Charlton, Stephen Paul Collingwood, Alexis Flen, Sarah Lilley, Michael J. Tuvim, Martin Gosling, Colin Williams, Camille Ehre, Henry Danahay, Burton F. Dickey, Roy Fox, Sarah Beaudoin, Kathryn Adley, Ejaz Ansari
The calcium-activated chloride channel TMEM16A enables chloride secretion across several transporting epithelia, including in the airway where it represents a therapeutic target for the treatment of cystic fibrosis. Additional roles for TMEM16A have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd15703a13ddc5f9a3a3baee2a719ac
