Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Roy Eerlings"'
Autor:
Elien Smeets, Shengyun Huang, Xiao Yin Lee, Erika Van Nieuwenhove, Christine Helsen, Florian Handle, Lisa Moris, Sarah El Kharraz, Roy Eerlings, Wout Devlies, Mathijs Willemsen, Leoni Bücken, Teresa Prezzemolo, Stephanie Humblet‐Baron, Arnout Voet, Anne Rochtus, Ann Van Schepdael, Francis deZegher, Frank Claessens
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2242-2253 (2022)
Abstract Background Cytochrome P450 4F3 (CYP4F3) is an ω‐hydroxylase that oxidizes leukotriene B4 (LTB4), prostaglandins, and fatty acid epoxides. LTB4 is synthesized by leukocytes and acts as a chemoattractant for neutrophils, making it an essent
Externí odkaz:
https://doaj.org/article/7d73d180cc02422d9887d30e1f9063be
Autor:
Frank Claessens, Steven Joniau, Hendrik Van Poppel, Tamara Lotan, R. Jeffrey Karnes, Wout Devlies, Sarah El Kharraz, Roy Eerlings, Elien Smeets, Stefaan Soenen, Bart Ghesquière, Florian Handle, Christine Helsen, Diether Lambrechts, Bram Boeckx, Elai Davicioni, Thomas Gevaert, Lisa Moris, Thomas Van den Broeck
Supplementary Figure from Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fb929de242e188ca48cca0e68e30ff
https://doi.org/10.1158/1541-7786.22527972.v1
https://doi.org/10.1158/1541-7786.22527972.v1
Autor:
Frank Claessens, Steven Joniau, Hendrik Van Poppel, Tamara Lotan, R. Jeffrey Karnes, Wout Devlies, Sarah El Kharraz, Roy Eerlings, Elien Smeets, Stefaan Soenen, Bart Ghesquière, Florian Handle, Christine Helsen, Diether Lambrechts, Bram Boeckx, Elai Davicioni, Thomas Gevaert, Lisa Moris, Thomas Van den Broeck
Supplementary Table from Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b98852ba29378f2a895ab76be6a1f8
https://doi.org/10.1158/1541-7786.22527966
https://doi.org/10.1158/1541-7786.22527966
Autor:
Arnout Voet, Frank Claessens, Frederic Rousseau, Joost Schymkowitz, Nikolaos Louros, Roy Eerlings, Xiao Yin Lee, Tien T. Nguyen, Christine Helsen
Supplementary Figure from Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3808fce1021abdae7dcb70c020458f
https://doi.org/10.1158/1535-7163.22523613.v1
https://doi.org/10.1158/1535-7163.22523613.v1
Autor:
Arnout Voet, Frank Claessens, Frederic Rousseau, Joost Schymkowitz, Nikolaos Louros, Roy Eerlings, Xiao Yin Lee, Tien T. Nguyen, Christine Helsen
Supplementary Table from Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccc89870fb38ae2befc4e3c49147bd4
https://doi.org/10.1158/1535-7163.22523595
https://doi.org/10.1158/1535-7163.22523595
Autor:
Frank Claessens, Steven Joniau, Hendrik Van Poppel, Tamara Lotan, R. Jeffrey Karnes, Wout Devlies, Sarah El Kharraz, Roy Eerlings, Elien Smeets, Stefaan Soenen, Bart Ghesquière, Florian Handle, Christine Helsen, Diether Lambrechts, Bram Boeckx, Elai Davicioni, Thomas Gevaert, Lisa Moris, Thomas Van den Broeck
Supplementary Data from Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc5b56f1a6176f5b830bfd69f7644c6
https://doi.org/10.1158/1541-7786.22527978.v1
https://doi.org/10.1158/1541-7786.22527978.v1
Autor:
Christine Helsen, Maria Santa Rocca, Tien T. Nguyen, Roy Eerlings, Xiao Yin Lee, Sofie De Block, Cinzia Vinanzi, Francesco Di Millo, Vito Giagulli, Arnout Voet, Alberto Ferlin, Frank Claessens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e6efaf86b281971d2f8ad33afab31f
https://hdl.handle.net/11577/3474150
https://hdl.handle.net/11577/3474150
Autor:
Sarah El Kharraz, Vanessa Dubois, Kaisa-Mari Launonen, Laura Helminen, Jorma J Palvimo, Claude Libert, Elien Smeets, Lisa Moris, Roy Eerlings, Dirk Vanderschueren, Christine Helsen, Frank Claessens
Publikováno v:
Endocrinology
ENDOCRINOLOGY
ENDOCRINOLOGY
The androgen receptor (AR) plays a central role in the development and maintenance of the male phenotype. The binding of androgens to the receptor induces interactions between the carboxyterminal ligand-binding domain and the highly conserved 23FQNLF
Autor:
Frank Claessens, Roy Eerlings, Purvi Gupta, Xiao Yin Lee, Sarah E Kharraz, Maarten Jacquemyn, Bram Vandewinkel, Sofie D Munter, Tien Nguyen, Florian Handle, Elien Smeets, Lisa Moris, Wout Devlies, Karin Voordeckers, Anton Gorkovskiy, Els Henckaerts, Dirk Daelemans, Kevin J Verstrepen, Arnout Voet, Christine Helsen
Publikováno v:
Journal of the Endocrine Society. 6:A729-A730
In synthetic biology, small molecules are commonly used for altering gene expression through the (in)activation of gene switches. Current switches, however, have a narrow species range, are non-titratable, or use non-inert inducers which evoke import
Autor:
Christine Helsen, Tien T. Nguyen, Xiao Yin Lee, Roy Eerlings, Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau, Frank Claessens, Arnout Voet
Publikováno v:
Molecular cancer therapeutics. 21(12)
Currently, all clinically used androgen receptor (AR) antagonists target the AR ligand-binding pocket and inhibit T and dihydrotestosterone (DHT) binding. Resistance to these inhibitors in prostate cancer frequently involves AR-dependent mechanisms r