Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Roy D. Welch"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Bacterial-derived polyketide and non-ribosomal peptide natural products are crucial sources of therapeutics and yet little is known about the conditions that favor activation of natural product genes or the regulatory machinery controlling t
Externí odkaz:
https://doaj.org/article/e8349d92f1ef40f8a46f119ddb48ef11
Autor:
Jiangguo Zhang, Jessica A. Comstock, Christopher R. Cotter, Patrick A. Murphy, Weili Nie, Roy D. Welch, Ankit B. Patel, Oleg A. Igoshin
Publikováno v:
Microorganisms, Vol 9, Iss 9, p 1954 (2021)
Myxococcus xanthus bacteria are a model system for understanding pattern formation and collective cell behaviors. When starving, cells aggregate into fruiting bodies to form metabolically inert spores. During predation, cells self-organize into trave
Externí odkaz:
https://doaj.org/article/500140330bef456e8ab0adfbc1f388e5
Autor:
Aaron D. Skewes, Roy D. Welch
Publikováno v:
PeerJ, Vol 1, p e127 (2013)
The arrangement of nucleotides within a bacterial chromosome is influenced by numerous factors. The degeneracy of the third codon within each reading frame allows some flexibility of nucleotide selection; however, the third nucleotide in the triplet
Externí odkaz:
https://doaj.org/article/19cdce595cbd40c3afc351f61dcb685c
Autor:
Merrill E. Asp, Minh-Tri Ho Thanh, Subarna Dutta, Jessica A. Comstock, Roy D. Welch, Alison E. Patteson
Publikováno v:
Biophysics Reviews. 4
The central hypothesis of the genotype–phenotype relationship is that the phenotype of a developing organism (i.e., its set of observable attributes) depends on its genome and the environment. However, as we learn more about the genetics and bioche
The genotype-to-phenotype problem (G2P) for multicellular development asks how genetic inputs control collective phenotypic outputs. It is a difficult problem even to observe. On the genotype side, the phenotypic impact of mutation is often subtle du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ad73b07a4beea47dbddb6c826fdcf5
https://doi.org/10.1101/2023.02.26.530117
https://doi.org/10.1101/2023.02.26.530117
Autor:
Muqing Ma, Anthony G. Garza, David J. Lemon, Eduardo A. Caro, Linnea Ritchie, Charles Ryan, Victoria M. Spearing, Kimberly A. Murphy, Roy D. Welch
Publikováno v:
Journal of Bacteriology. 204
Myxococcus xanthus copes with starvation by producing fruiting bodies filled with dormant and stress-resistant spores. Here, we aimed to better define the gene regulatory network associated with Nla28, a transcriptional activator/enhancer binding pro
Autor:
Jessica A. Comstock, Merrill E. Asp, Fatmagül Bahar, Isabella Lee, Alison E. Patteson, Roy D. Welch
Robustness to the impact of mutation can mitigate phenotypes that have the potential to inform gene function. This robustness is often encoded into the genome through gene duplication, among other mechanisms. Duplication is a source of structurally s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2c0cea819509814ca8b5685e7ae0fca
https://doi.org/10.1101/2022.07.25.501402
https://doi.org/10.1101/2022.07.25.501402
Autor:
Merrill E Asp, Minh-Tri Ho Thanh, Danielle A Germann, Robert J Carroll, Alana Franceski, Roy D Welch, Arvind Gopinath, Alison E Patteson
Publikováno v:
PNAS Nexus. 1
The ability of bacteria to colonize and grow on different surfaces is an essential process for biofilm development. Here, we report the use of synthetic hydrogels with tunable stiffness and porosity to assess physical effects of the substrate on biof
Autor:
Roy D. Welch, David J. Lemon, Charles Ryan, Muqing Ma, Anthony G. Garza, Ting Li, Eduardo A. Caro, Victoria M. Spearing, Kimberly A. Murphy, Linnea J. Ritchie
Organisms frequently encounter environments with nutrient shortages and their survival depends on changes in physiology and the ability to conserve resources. In bacteria, many physiological changes associated with starvation have been identified, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c94ab4cc8339b3aaed02e2e5356d46f1
https://doi.org/10.1101/2021.11.28.470282
https://doi.org/10.1101/2021.11.28.470282
Autor:
Christopher R. Cotter, Roy D. Welch, Weili Nie, Patrick A. Murphy, Jiangguo Zhang, Ankit B. Patel, Jessica A. Comstock, Oleg A. Igoshin
Publikováno v:
Microorganisms, Vol 9, Iss 1954, p 1954 (2021)
Microorganisms
Volume 9
Issue 9
Microorganisms
Volume 9
Issue 9
Myxococcus xanthus bacteria are a model system for understanding pattern formation and collective cell behaviors. When starving, cells aggregate into fruiting bodies to form metabolically inert spores. During predation, cells self-organize into trave