Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Roy C. P. Kerckhoffs"'
Autor:
Roy C. P. Kerckhoffs, Heather Y. Sun, Sukriti Dewan, Adarsh Krishnamurthy, Giulia Conca, Vishal Nigam, Jeffrey H. Omens, Devleena Kole, Michael D. Puchalski, Andrew D. McCulloch
Publikováno v:
Frontiers in Pediatrics
Introduction Hypoplastic left heart syndrome (HLHS) is a congenital condition with an underdeveloped left ventricle (LV) that provides inadequate systemic blood flow postnatally. The development of HLHS is postulated to be due to altered biomechanica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662834f19442d4c4a123a3b0639e86b1
http://europepmc.org/articles/PMC5319967
http://europepmc.org/articles/PMC5319967
Autor:
Andrew D. McCulloch, Benjamin A. Coppola, Jeffrey H. Omens, Roy C. P. Kerckhoffs, Jared R. Tangney, Adarsh Krishnamurthy
Publikováno v:
Structure-Based Mechanics of Tissues and Organs ISBN: 9781489976291
Contraction of cardiac muscle cells provides the work for ventricular pumping. The primary component of this contractile stress development in myocardium acts along the axis of the myofilaments; however, there may be a component directed transversely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5349ceaed135f26da35bb457b8170450
https://doi.org/10.1007/978-1-4899-7630-7_22
https://doi.org/10.1007/978-1-4899-7630-7_22
Autor:
Jeffrey H. Omens, Roy C. P. Kerckhoffs, James W. Covell, Lawrence J. Mulligan, Elliot J. Howard, Andrew D. McCulloch
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H1447-H1455
Recently, attention has been focused on comparing left ventricular (LV) endocardial (ENDO) with epicardial (EPI) pacing for cardiac resynchronization therapy. However, the effects of ENDO and EPI lead placement at multiple sites have not been studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da762959738e370335b7d0cf5384aca5
https://doi.org/10.1152/ajpheart.00295.2011
https://doi.org/10.1152/ajpheart.00295.2011
Autor:
Roy C. P. Kerckhoffs, Lawrence J. Mulligan, Elliot J. Howard, Stuart G. Campbell, Jazmin Aguado-Sierra, Jeffrey H. Omens, Benjamin A. Coppola, Andrew D. McCulloch
Publikováno v:
Experimental Physiology. 94:541-552
The excitation-contraction coupling properties of cardiac myocytes isolated from different regions of the mammalian left ventricular wall have been shown to vary considerably, with uncertain effects on ventricular function. We embedded a cell-level e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fac3267de914d48d4bcab462d7e3fdd
https://doi.org/10.1113/expphysiol.2008.044057
https://doi.org/10.1113/expphysiol.2008.044057
Publikováno v:
Medical Image Analysis. 13:362-369
To study the impact of biventricular pacing (BiV) and scar size on left ventricular (LV) regional and global function using a detailed finite element model of three-dimensional electromechanics in the failing canine heart.Cardiac resynchronization th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1be2edc116d8916f3f08312a6439a0
https://doi.org/10.1016/j.media.2008.06.013
https://doi.org/10.1016/j.media.2008.06.013
Autor:
Roy C. P. Kerckhoffs, Lawrence J. Mulligan, Jeffrey H. Omens, Sanjiv M. Narayan, Andrew D. McCulloch
Publikováno v:
Heart Failure Clinics. 4:371-378
Advances in computer power, novel diagnostic and therapeutic medical technologies, and an increasing knowledge of pathophysiology from gene to organ systems make it increasingly feasible to apply multiscale patient-specific modeling based on proven d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4790fcc8d007c4a093fc4075c080e6
https://doi.org/10.1016/j.hfc.2008.02.009
https://doi.org/10.1016/j.hfc.2008.02.009
Autor:
Taras P. Usyk, Christopher M. Ingrassia, Roy C. P. Kerckhoffs, Andrew D. McCulloch, Jeffrey W. Holmes, Kevin D. Costa
Publikováno v:
Computer Methods in Applied Mechanics and Engineering. 196:3061-3069
Engineers and cardiologists have taken divergent approaches to analysis of regional heart function. Our group is interested in developing clinically useful quantitative measures of endocardial wall motion, which is routinely assessed qualitatively by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ed38d92b3f762bfec12cefb8997dfc
https://doi.org/10.1016/j.cma.2006.06.016
https://doi.org/10.1016/j.cma.2006.06.016
Publikováno v:
Proceedings of the IEEE. 94:769-783
Computational modeling provides a potentially powerful way to integrate structural properties measured in vitro to physiological functions measured in vivo. Focusing on the various scales (cell-tissue-organ-system), we give an overview of the importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1427d9c4093af2598323c848f57aa8b
https://doi.org/10.1109/jproc.2006.871772
https://doi.org/10.1109/jproc.2006.871772
Autor:
K. Smits, Theo Arts, Peter H. M. Bovendeerd, Elliot R. McVeigh, Frits W. Prinzen, Roy C. P. Kerckhoffs, Owen P. Faris
Publikováno v:
American Journal of Physiology : Heart and Circulatory Physiology, 289(5), H1889-H1897. American Physiological Society
Intraventricular synchrony of cardiac activation is important for efficient pump function. Ventricular pacing restores the beating frequency but induces more asynchronous depolarization and more inhomogeneous contraction than in the normal heart. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67893288c99eaeae150f016c38bb88e
https://doi.org/10.1152/ajpheart.00340.2005
https://doi.org/10.1152/ajpheart.00340.2005
Publikováno v:
Annals of the New York Academy of Sciences, 1015(2004), 190-201. Wiley-Blackwell
The invariant nature of body situs within and across vertebrate species implies that a highly conserved pathway controls the specification of the left-right (L/R) axis. Situs-specific morphogenesis begins at the end of this pathway and leads to norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91114fb1e08033c22a7779ad51dfecf3
https://doi.org/10.1196/annals.1302.016
https://doi.org/10.1196/annals.1302.016