Výsledky vyhledávání - "Roy C K, Kong"

Akademický článek

Transcriptomic analysis of choroidal neovascularization reveals dysregulation of immune and fibrosis pathways that are attenuated by a novel anti-fibrotic treatment

Autor: Alice Brandli, Fay L. Khong, Roy C. K. Kong, Darren J. Kelly, Erica L. Fletcher

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract Neovascular AMD (nAMD) leads to vision loss and is a leading cause of visual impairment in the industrialised world. Current treatments that target blood vessel growth have not been able to treat subretinal fibrosis and nAMD patients continu

Externí odkaz: https://doaj.org/article/9c321a43bb704a35b001b8c5b72cf379

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Inhibitory Effects of 3′,4′-Dihydroxyflavonol in a Mouse Model of Glaucoma Filtration Surgery and TGFβ1-Induced Responses in Human Tenon's Fibroblasts

Autor: Jennifer C, Fan Gaskin, Roy C K, Kong, Manisha H, Shah, Amanda J, Edgley, Hitesh M, Peshavariya, Elsa C, Chan

Publikováno v: Translational Vision Science & Technology. 11:18

Cytotoxic agents such as mitomycin C (MMC) are part of the mainstay treatment for limiting subconjunctival scarring following glaucoma filtration surgery (GFS). However, a safer antifibrotic therapy is clinically needed. The anti-scarring properties

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b238c7cf40b48b03019ad96c55ac70f
https://doi.org/10.1167/tvst.11.8.18

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