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pro vyhledávání: '"Roy Buchanan"'
Autor:
Eugene Futai, Erik L. Snapp, Randy Schekman, Robert J.D. Reid, Rodney Rothstein, Susan Hamamoto, Jennifer G. D’Arcangelo, Silvere Pagant, John C. Dittmar, Leslie Kung, Roy Buchanan, Elizabeth A. Miller
Publikováno v:
The EMBO Journal. 31:1014-1027
Vesicle budding from the endoplasmic reticulum (ER) employs a cycle of GTP binding and hydrolysis to regulate assembly of the COPII coat. We have identified a novel mutation (sec24-m11) in the cargo-binding subunit, Sec24p, that specifically impacts
Genetic Analysis of Yeast Sec24p Mutants Suggests Cargo Binding Is Not Co-operative during ER Export
Publikováno v:
Traffic. 11:1034-1043
Many eukaryotic secretory proteins are selected for export from the endoplasmic reticulum (ER) through their interaction with the Sec24p subunit of the coat protein II (COPII) coat. Three distinct cargo-binding sites on yeast Sec24p have been describ