Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Roy A. Wise"'
Autor:
Roy A. Wise, Chloe J. Jordan
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-9 (2021)
Abstract Addictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to addictive drugs can stamp in learning. Dopamine-depleted or dopamine-deleted animals have only unlearned reflexes; they lack learned seeking and learned
Externí odkaz:
https://doaj.org/article/a86746c1959846f78a0a2078817d0069
Autor:
Chloe J. Jordan, Roy A. Wise
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-9 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
Addictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to addictive drugs can stamp in learning. Dopamine-depleted or dopamine-deleted animals have only unlearned reflexes; they lack learned seeking and learned avoidanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d4ef2c5a2c37f26a018728b3232a0d
https://doaj.org/article/a86746c1959846f78a0a2078817d0069
https://doaj.org/article/a86746c1959846f78a0a2078817d0069
Autor:
Roy A Wise, Mykel A. Robble
Publikováno v:
Annual Review of Psychology. 71:79-106
Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is usually defined by characteristics of intoxication or by characteristics of withdrawal symptoms. Such addictions can also be defined in terms of the brain m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ab96a196a1841cab24654a80053d8f
https://doi.org/10.1146/annurev-psych-010418-103337
https://doi.org/10.1146/annurev-psych-010418-103337
Autor:
Zhi-Bing You, Ewa Galaj, Francisco Alén, Bin Wang, Guo-Hua Bi, Allamar R. Moore, Tristram Buck, Madeline Crissman, Sruti Pari, Zheng-Xiong Xi, Lorenzo Leggio, Roy A. Wise, Eliot L. Gardner
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47(8)
Cocaine addiction is a significant medical and public concern. Despite decades of research effort, development of pharmacotherapy for cocaine use disorder remains largely unsuccessful. This may be partially due to insufficient understanding of the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3270c80b30e895e563d7c2328e3379e0
https://pubmed.ncbi.nlm.nih.gov/34923576
https://pubmed.ncbi.nlm.nih.gov/34923576
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84412 (2014)
Cholinergic input to the ventral tegmental area (VTA) is known to contribute to reward. Although it is known that the pedunculopontine tegmental nucleus (PPTg) provides an important source of excitatory input to the dopamine system, the specific role
Externí odkaz:
https://doaj.org/article/2d2a4cdb2121428a8320c5074a575eaa
Autor:
Wendy Xin, Roy A. Wise, Hui Shen, Antonello Bonci, Marco Pignatelli, Rosa Anna Maria Marino, Stephanie C. Gantz, Ross A. McDevitt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Stimulation of lateral hypothalamic (LH) neurons produces eating in sated animals and increases activity of dopamine neurons. The present study shows that the activation of dopamine neurons failed to induce eating. Rather, food approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0ba9e7db1acc849db7280019435ff1
https://pubmed.ncbi.nlm.nih.gov/32229573
https://pubmed.ncbi.nlm.nih.gov/32229573
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2846 (2008)
Intravenous injections of cocaine HCl are habit-forming because, among their many actions, they elevate extracellular dopamine levels in the terminal fields of the mesocorticolimbic dopamine system. This action, thought to be very important for cocai
Externí odkaz:
https://doaj.org/article/5334520db47f430e8b00bb75e147b284
Publikováno v:
Pharmacol Biochem Behav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25fac739d2071e584adeaccc802f515
https://doi.org/10.1016/j.pbb.2021.173187
https://doi.org/10.1016/j.pbb.2021.173187
Publikováno v:
Nature Reviews Neuroscience. 18:741-752
Behaviours such as eating, copulating, defending oneself or taking addictive drugs begin with a motivation to initiate the behaviour. Both this motivational drive and the behaviours that follow are influenced by past and present experience with the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410af60d481bd48adb9fab6d0aef1943
https://doi.org/10.1038/nrn.2017.130
https://doi.org/10.1038/nrn.2017.130
Autor:
Garret D. Stuber, Roy A. Wise
Publikováno v:
Nature Neuroscience. 19:198-205
In experiments conducted over 60 years ago, the lateral hypothalamic area (LHA) was identified as a critical neuroanatomical substrate for motivated behavior. Electrical stimulation of the LHA induces voracious feeding even in non-restricted animals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706899ffad052a927c25f6a40c4ea0b2
https://doi.org/10.1038/nn.4220
https://doi.org/10.1038/nn.4220