Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Roy A. Tassava"'
Publikováno v:
Wound Repair and Regeneration. 14:479-483
Adult newt limbs that are denervated 1 day after amputation undergo a wound-healing response and, although they become reinnervated, will not regenerate unless reinjured. Experiments were designed to determine when denervated limb stumps of adult new
Autor:
Roy A. Tassava, Yan Huang
Publikováno v:
Journal of Experimental Zoology Part A: Comparative Experimental Biology. :1031-1039
Spinal axons of the adult newt will regenerate when the spinal cord is severed or when the tail is amputated. Ischemia and associated hypoxia have been correlated with poor central nervous system regeneration in mammals. To test the effects of ischem
Autor:
C.L. Olsen-Winner, Roy A. Tassava
Publikováno v:
Journal of Experimental Zoology. :64-79
The developing neural tubes and associated neural crest cells were removed from stage 30 Ambystoma maculatum embryos to obtain larvae with aneurogenic forelimbs. Forelimbs were allowed to develop to late 3 digit or early 4 digit stages. Limbs amputat
Publikováno v:
Developmental Dynamics. 223:193-203
Members of the fibroblast growth factor (FGF) family of molecules are critical to limb outgrowth. Here, we examine the expression of Fgfs in three types of limbs-embryonic (developing), mature (differentiated), and regenerating-as well as in the surr
Autor:
Essam El-Din A. Moussad, Roy A. Tassava, Sarah E. Abbey, Mona A.E. Rageh, Luciara Mendenhall, Anthony L. Mescher
Publikováno v:
Journal of Experimental Zoology. 292:255-266
Immunocytochemistry utilizing a monoclonal antibody (BV1; blood vessel 1) highly reactive to the vasculature of the adult newt showed that a developing vasculature was present during early, pre-blastema, and early-bud blastema stages of forelimb rege
Publikováno v:
Journal of Experimental Zoology. 290:529-540
Urodele amphibians (newts and salamanders) have the ability to regenerate amputated limbs throughout their life span. Because fibroblast growth factors (Fgfs) play important roles in developing limbs, we initiated studies to investigate these growth
Publikováno v:
Developmental Dynamics. 217:216-224
Urodele amphibians (salaman- ders) are unique among adult vertebrates in their ability to regenerate limbs. The regener- ated structure is often indistinguishable from the developmentally produced original. Thus, the two processes by which the limb i
Autor:
Kathleen M. Gassner, Roy A. Tassava
Publikováno v:
The Journal of Experimental Zoology. 279:571-578
Limb regeneration in the short-toes axolotl is impaired. Our goal was to characterize the regeneration process in this mutant by histological and immunocytochemical methods. Previous research indicates that age and a defective basement membrane may b
Publikováno v:
The Journal of Experimental Zoology. 279:71-80
Monoclonal antibodies (mAbs) MT1 and MT2 provided the opportunity to compare developing and regenerating limbs with regard to the temporal and spatial appearance of the developmentally regulated, extracellular matrix (ECM) proteins tenascin (TN) and
Autor:
Roy A. Tassava, Yi Wei
Publikováno v:
Journal of Morphology. 230:177-186
Previously we showed that type XII collagen (col XII) is highly upregulated in the regenerating newt (Notophthalmus viridescens) forelimb. Here, using immunohistochemistry and in situ hybridization, we studied the pattern of expression of col XII dur