Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Roy A, Fava"'
Autor:
Sabrina Ceeraz, Susan K. Eszterhas, Petra A. Sergent, David A. Armstrong, Alix Ashare, Thomas Broughton, Li Wang, Dov Pechenick, Christopher M. Burns, Randolph J. Noelle, Matthew P. Vincenti, Roy A. Fava
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Abstract Background In addition to activated T cells, the immune checkpoint inhibitor “V domain-containing Ig suppressor of T-cell activation” (VISTA) is expressed by myeloid cell types, including macrophages and neutrophils. The importance of VI
Externí odkaz:
https://doaj.org/article/5d72d8c1bf0948c0bbccc700bc1f2200
Autor:
Shima Shahbaz, Najmeh Bozorgmehr, Petya Koleva, Afshin Namdar, Juan Jovel, Roy A Fava, Shokrollah Elahi
Publikováno v:
PLoS Biology, Vol 16, Iss 12, p e2006649 (2018)
Cell-surface transferrin receptor (CD71+) erythroid cells are abundant in newborns with immunomodulatory properties. Here, we show that neonatal CD71+ erythroid cells express significant levels of V-domain Immunoglobulin (Ig) Suppressor of T Cell Act
Externí odkaz:
https://doaj.org/article/80e444f65d154ccc9ce2e677faf06f16
CD71+VISTA+ erythroid cells promote the development and function of regulatory T cells through TGF-β
Autor:
Roy A. Fava, Shokrollah Elahi, Juan Jovel, Shima Shahbaz, Petya Koleva, Afshin Namdar, Najmeh Bozorgmehr
Publikováno v:
PLoS Biology, Vol 16, Iss 12, p e2006649 (2018)
PLoS Biology
PLoS Biology
Cell-surface transferrin receptor (CD71+) erythroid cells are abundant in newborns with immunomodulatory properties. Here, we show that neonatal CD71+ erythroid cells express significant levels of V-domain Immunoglobulin (Ig) Suppressor of T Cell Act
Autor:
Randolph J. Noelle, Susan K. Eszterhas, Li Wang, Christopher M. Burns, David A. Armstrong, Alix Ashare, Matthew P. Vincenti, Petra A. Sergent, Sabrina Ceeraz, Thomas Broughton, Dov A. Pechenick, Roy A. Fava
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Background In addition to activated T cells, the immune checkpoint inhibitor “V domain-containing Ig suppressor of T-cell activation” (VISTA) is expressed by myeloid cell types, including macrophages and neutrophils. The importance of VISTA expre
Autor:
Abigail M. Fellows, Peter M. Morganelli, Ralph C. Nichols, Brenda L. Petrella, R. Brooks Robey, Lihui Zhong, Roy A. Fava, Mary E. Griffin, Fatemeh P. Parvin-Nejad
Publikováno v:
Molecular Biology of the Cell
Vascular endothelial growth factor (VEGF) expression is regulated by sequence elements in the 3′ UTR of VEGF mRNA. AUF1/hnRNP D suppresses VEGF 3′ UTR–dependent expression. Peptides with arginine–glycine–glycine motifs derived from AUF1 als
Autor:
Roy A. Fava, Sally A. Huber, John A. Kelly, Joseph L. Witztum, Katherine A. Bessette, Elizabeth R. Miller, Sheryl G. Wood, Christoph J. Binder, Mary E. Griffin, Peter M. Morganelli
Publikováno v:
Cardiovascular Research. 85:224-231
Aims Given the importance of IgG Fc receptors in immune regulation, we hypothesized that Fcg receptor type III (FcgRIII, CD16) plays an important role in atherogenesis. We therefore analysed the formation of arterial lesions in LDL receptor-deficient
Autor:
Warren J. Leonard, Katherine A. Bessette, Jennifer Heinen, Roy A. Fava, Amin Al-Shami, Laurie Horne, Rosanne Spolski, Martin Grundy, Mark L. Lang, Herbert C. Morse, John A. Kelly
Publikováno v:
Blood. 111:344-350
Stat5 proteins are critical signaling molecules activated by many cytokines. Within the immune system, Stat5 plays important roles related to the development of thymocytes and proliferation of T cells. Stat5 has been implicated in malignant transform
Autor:
Jane A. Hunt, Norm Allaire, Roy A. Fava, Steven Perrin, Jeffrey L. Browning, Apinya Ngam-ek, Evangelia Notidis
Publikováno v:
Immunity. 23:539-550
The lymphotoxin axis is important for the maintenance of several specialized lymphoid microenvironments in secondary lymphoid tissue. Lymphoid-tissue architecture is highly plastic and requires continual homeostatic signaling to maintain its basal fu
Autor:
Julieta Gentiletti, Roy A. Fava
Publikováno v:
Arthritis & Rheumatism. 48:1471-1474
Publikováno v:
Clinical and Experimental Immunology. 115:176-182
SUMMARYVascular endothelial growth factor (VEGF) is abundant in synovium and synovial fluids, where it probably contributes to vascular permeability and angiogenesis in arthritic joints. To investigate the probable sources of VEGF in synovium, we com