Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Roy, Valentine"'
Autor:
Bertrand, Sylvain, Penco, Luigi, Anderson, Dexton, Calvert, Duncan, Roy, Valentine, McCrory, Stephen, Mohammed, Khizar, Sanchez, Sebastian, Griffith, Will, Morfey, Steve, Maslyczyk, Alexis, Mohan, Achintya, Castello, Cody, Ma, Bingyin, Suryavanshi, Kartik, Dills, Patrick, Pratt, Jerry, Ragusila, Victor, Shrewsbury, Brandon, Griffin, Robert
Teleoperation of humanoid robots has long been a challenging domain, necessitating advances in both hardware and software to achieve seamless and intuitive control. This paper presents an integrated solution based on several elements: calibration-fre
Externí odkaz:
http://arxiv.org/abs/2409.04639
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1851-1862 (2016)
The synthesis of novel tetrahydroquinolines (THQ) and dihydroquinolines (DHQ) are reported using three practical, scalable synthetic approaches to access highly lipophilic analogues bearing a 6-iodo substituent, each with a different means of cyclisa
Externí odkaz:
https://doaj.org/article/4af96c935824420eac40a501c68548f3
Autor:
Natalie J. Tatum, Ehmke Pohl, Christopher P.F. Redfern, Roy Valentine, David R. Chisholm, Andrew Whiting, Stefan Przyborski, Hesham Haffez
Publikováno v:
Bioorganic & Medicinal Chemistry
Bioorganic and medicinal chemistry, 2018, Vol.26(8), pp.1560-1572 [Peer Reviewed Journal]
Bioorganic and medicinal chemistry, 2018, Vol.26(8), pp.1560-1572 [Peer Reviewed Journal]
Graphical abstract
Retinoids, such as all-trans-retinoic acid (ATRA), regulate cellular differentiation and signalling pathways in chordates by binding to nuclear retinoic acid receptors (RARα/β/γ). Polar interactions between receptor and lig
Retinoids, such as all-trans-retinoic acid (ATRA), regulate cellular differentiation and signalling pathways in chordates by binding to nuclear retinoic acid receptors (RARα/β/γ). Polar interactions between receptor and lig
Autor:
David R, Chisholm, Charles W E, Tomlinson, Garr-Layy, Zhou, Claire, Holden, Valerie, Affleck, Rebecca, Lamb, Katherine, Newling, Peter, Ashton, Roy, Valentine, Christopher, Redfern, János, Erostyák, Geza, Makkai, Carrie A, Ambler, Andrew, Whiting, Ehmke, Pohl
Publikováno v:
ACS chemical biology. 14(3)
Retinoids, such as all- trans-retinoic acid (ATRA), are endogenous signaling molecules derived from vitamin A that influence a variety of cellular processes through mediation of transcription events in the cell nucleus. Because of these wide-ranging
Publikováno v:
Beilstein journal of organic chemistry, 2016, Vol.12, pp.1851-1862 [Peer Reviewed Journal]
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1851-1862 (2016)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1851-1862 (2016)
Beilstein Journal of Organic Chemistry
The synthesis of novel tetrahydroquinolines (THQ) and dihydroquinolines (DHQ) are reported using three practical, scalable synthetic approaches to access highly lipophilic analogues bearing a 6-iodo substituent, each with a different means of cyclisa
Publikováno v:
Journal of organic chemistry, 2016, Vol.81(17), pp.7557-7565 [Peer Reviewed Journal]
A convenient, mild and effective conjugate addition of 3-butyn-2-one to a variety of anilines in ethanol is reported. The reaction was monitored and characterized through in situ FTIR, and the dynamics of the facile E/Z alkene geometry interconversio
Autor:
Andrew Whiting, Ehmke Pohl, David R. Chisholm, Hesham Haffez, Roy Valentine, Christopher P.F. Redfern
Publikováno v:
MedChemComm, 2017, Vol.8(3), pp.578-592 [Peer Reviewed Journal]
All-trans-retinoic acid (ATRA) and its synthetic analogues EC23 and EC19 direct cellular differentiation by interacting as ligands for the retinoic acid receptor (RARα, β and γ) family of nuclear receptor proteins. To date, a number of crystal str
Autor:
Hernandez, Roy Valentine
Apolipoprotein E3 (apoE3) is an important anti-atherogenic protein that helps maintain cholesterol levels in the brain and plasma. It is responsible for binding and cellular uptake of plasma lipoproteins via the low-density lipoprotein receptor famil
Externí odkaz:
http://pqdtopen.proquest.com/#viewpdf?dispub=1584727
Autor:
Yuan Li, Gurdial Singh, Elizabeth V Welchman, Shende Jiang, Michael G. B. Drew, Rajeev K Shirvastava, Roy Valentine
Publikováno v:
Tetrahedron. 60:6523-6531
The difluorinated analogues of 3-deoxy- d -arabino-heptulosonic acid (DAH) 12 , 24 and its enantiomer have been synthesised from d - and l -erythrose via a Reformatsky reaction which gave a mixture of diastereoiosmers in favour of the anti isomer.
Autor:
Stefan Przyborski, Todd B. Marder, Garr-Layy Zhou, Daniel M. Tams, Andrew Whiting, Roy Valentine
Publikováno v:
Organic & biomolecular chemistry, 2013, Vol.11(14), pp.2323-2334 [Peer Reviewed Journal]
Understanding how the structure of molecules relates to their function and biological activity is essential in the development of new analogues with targeted activity. This is especially relevant in mediating developmental processes in mammalian cell