Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Roy, Freeman"'
Autor:
David Michelson, William W. Chin, Robert H. Dworkin, Roy Freeman, David N. Herrmann, Ralph Mazitschek, Rodica Pop-Busui, Aziz Shaibani, James Vornov, Melissa Jones, Matthew Jarpe, Brittany Hader, Theresa Viera, Michelle Hylan, Tim Kachmar, Simon Jones
Publikováno v:
PAIN Reports, Vol 8, Iss 6, p e1114 (2023)
Abstract. Introduction:. Current treatments for painful diabetic peripheral neuropathy (DPN) are insufficiently effective for many individuals and do not treat nonpain signs and symptoms. The enzyme histone deacetylase type 6 (HDAC6) may play a role
Externí odkaz:
https://doaj.org/article/43d645a10fbd4b539890e51d56390ee1
Autor:
Roy Freeman, Alejandra Gonzalez‐Duarte, Fabio Barroso, Marta Campagnolo, Sharika Rajan, Jennifer Garcia, Jee Young Kim, Ningshan Wang, Lucas Orellana, Christopher Gibbons
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 9, Pp 1370-1383 (2022)
Abstract Objective To determine the sensitivity and specificity of cutaneous amyloid deposition in relation to patient‐reported measures in the earliest disease stage of hereditary ATTR amyloidosis (ATTRv). Methods In a cross‐sectional study, we
Externí odkaz:
https://doaj.org/article/8b09026792cb4814b07a1bf400e47db4
Autor:
Catharina G. Faber, Nadine Attal, Giuseppe Lauria, Robert H. Dworkin, Roy Freeman, Katherine T. Dawson, Helen Finnigan, Amirhossein Hajihosseini, Himanshu Naik, Michael Serenko, Christopher J. Morris, Mona Kotecha
Publikováno v:
EClinicalMedicine, Vol 59, Iss , Pp 101971- (2023)
Summary: Background: No pharmacological treatments are specifically indicated for painful small fibre neuropathy (SFN). CONVEY, a phase 2 enriched-enrolment study, evaluated the efficacy and safety of vixotrigine, a voltage- and use-dependent sodium
Externí odkaz:
https://doaj.org/article/98dd54c83e884b6a959fad1b27b55fcf
Autor:
Sarah Zaheer, Kayla Meyer, Rebecca Easly, Omar Bayomy, Janet Leung, Andrew W Koefoed, Mahyar Heydarpour, Roy Freeman, Gail K Adler
Publikováno v:
Endocrine Connections, Vol 10, Iss 12, Pp 1607-1614 (2021)
Glucocorticoid use is the most common cause of secondary osteoporosis. Poor skeletal health related to glucocorticoid use is thought to involve inhibition of the Wnt/β-catenin signaling pathway, a key pathway in osteoblastogenesis. Sclerostin, a pep
Externí odkaz:
https://doaj.org/article/1bf73f99fd0c475fa1aabb93148c172e
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 4, Pp 908-917 (2021)
Abstract Objective To report a case series of patients with neuropathic POTS and cutaneous phosphorylated alpha‐synuclein (P‐SYN) deposition on skin biopsy and compare these to neuropathic POTS patients without P‐SYN deposition. Methods The med
Externí odkaz:
https://doaj.org/article/b418e90e36f74f30a2a94fd651ec9fd4
Autor:
Jennifer S. Gewandter, Robert R. Edwards, Kevin P. Hill, Ajay D. Wasan, Julia E. Hooker, Emma C. Lape, Soroush Besharat, Penney Cowan, Bernard Le Foll, Joseph W. Ditre, Roy Freeman
Publikováno v:
The Clinical Journal of Pain. 39:249-258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6c00ef79d39211f0bb95da271cc237
https://doi.org/10.1097/ajp.0000000000001109
https://doi.org/10.1097/ajp.0000000000001109
Autor:
Robert R. Edwards, Robert H. Dworkin, Dennis C. Turk, Martin S. Angst, Raymond Dionne, Roy Freeman, Per Hansson, Simon Haroutounian, Lars Arendt-Nielsen, Nadine Attal, Ralf Baron, Joanna Brell, Shay Bujanover, Laurie B. Burke, Daniel Carr, Amy S. Chappell, Penney Cowan, Mila Etropolski, Roger B. Fillingim, Jennifer S. Gewandter, Nathaniel P. Katz, Ernest A. Kopecky, John D. Markman, George Nomikos, Linda Porter, Bob A. Rappaport, Andrew S.C. Rice, Joseph M. Scavone, Joachim Scholz, Lee S. Simon, Shannon M. Smith, Jeffrey Tobias, Tina Tockarshewsky, Christine Veasley, Mark Versavel, Ajay D. Wasan, Warren Wen, David Yarnitsky
Publikováno v:
PAIN Reports, Vol 6, Iss 1, p e899 (2021)
Abstract. There is tremendous interpatient variability in the response to analgesic therapy (even for efficacious treatments), which can be the source of great frustration in clinical practice. This has led to calls for “precision medicine” or pe
Externí odkaz:
https://doaj.org/article/daf3aa186f274684ac1ec5b80f599fe5
Autor:
Timo Siepmann, Martin Arndt, Annahita Sedghi, Szabolcs Szatmári, Tamás Horváth, Annamária Takáts, Dániel Bereczki, Mats Leif Moskopp, Sylvia Buchmann, Cornelia Skowronek, Wagner Zago, Warunya Woranush, Razvan Lapusca, Marie Luise Weidemann, Christopher H. Gibbons, Roy Freeman, Heinz Reichmann, Volker Puetz, Kristian Barlinn, Alexandra Pintér, Ben Min‐Woo Illigens
Publikováno v:
European Journal of Neurology. 30:1281-1292
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75febb0fe164377e619664c5b7cb799d
https://doi.org/10.1111/ene.15733
https://doi.org/10.1111/ene.15733
Autor:
Julia Forstenpointner, Anne Margarette S. Maallo, Igor Elman, Scott Holmes, Roy Freeman, Ralf Baron, David Borsook
Publikováno v:
European Journal of Neuroscience. 56:3938-3966
The nucleus tractus solitarius (NTS) is a key brainstem structure relaying interoceptive peripheral information to the interrelated brain centres for eliciting rapid autonomic responses and for shaping longer-term neuroendocrine and motor patterns. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffa4de749d808c955229d19554618ea
https://doi.org/10.1111/ejn.15691
https://doi.org/10.1111/ejn.15691
Publikováno v:
Biomark Med
Finding an easily accessible and reliable tool to diagnose the diseases collectively defined as ‘synucleinopathies’ is an urgent, unmet priority. The synucleinopathies include Parkinson's disease, multiple system atrophy, pure autonomic failure a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50194c344e39c232baec22547d3b0625
https://pubmed.ncbi.nlm.nih.gov/35272481
https://pubmed.ncbi.nlm.nih.gov/35272481