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pro vyhledávání: '"Roy, Curtis"'
Akademický článek
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Publikováno v:
Journal of the American Society of Brewing Chemists; 2023, Vol. 81 Issue 3, p480-492, 13p
Akademický článek
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Publikováno v:
Tetrahedron Letters. 47:2635-2638
8-Azabicyclo[3.2.1]oct-3-en-2-ones were prepared by asymmetric 1,3-dipolar cycloadditions of homochiral pyridinium betaine 4 . Excellent diastereofacial selectivity was achieved for the major 6-exo cycloadducts. The absolute stereochemistry of cycloa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d64b145f5209e64649333852f4845c18
https://doi.org/10.1016/j.tetlet.2006.02.005
https://doi.org/10.1016/j.tetlet.2006.02.005
Autor:
Rodney A. Bednar, Roger M. Freidinger, John A. McCauley, Keith A. Wafford, David A. Claremon, Christopher F. Claiborne, Brian E. Libby, Stuart R. Michelson, Alison J. Macaulay, Nigel J. Liverton, Thomas M. Connolly, Bohumil Bednar, Kenneth S. Koblan, Stanley L. Gaul, Scott D. Mosser, Joseph J. Lynch, Cindra L. Condra, Gary L. Stump, Helen J. Diggle, Janusz Jozef Kulagowski, Kenneth D. Anderson, Neil Roy Curtis
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:697-700
A novel series of benzamidines was synthesized and shown to exhibit NR2B-subtype selective NMDA antagonist activity. Compound 31 is orally active in a carrageenan-induced rat hyperalgesia model of pain and shows no motor coordination side effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd299167537625261e03641a62d5a8a0
https://doi.org/10.1016/s0960-894x(02)01061-2
https://doi.org/10.1016/s0960-894x(02)01061-2
Autor:
Roy Curtis
Publikováno v:
Mental Health Review Journal. 2:18-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a28114532c72be15d6346af767091254
https://doi.org/10.1108/13619322199700026
https://doi.org/10.1108/13619322199700026
Autor:
Andrew N. Payne, Andrew B. Holmes, Craig L. Francis, Neil Roy Curtis, Jonathan W. Burton, Miles S. Congreve, S. Y. Frankie Mak
Publikováno v:
Synthesis. :3199-3201
A synthesis of the halogenated medium-ring ether natural product (+)-obtusenyne is reported utilizing a Claisen rearrangement and an intramolecular hydrosilation as key steps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173b686cb74f8e79a76d22c10953f27c
https://doi.org/10.1055/s-2005-918470
https://doi.org/10.1055/s-2005-918470
Autor:
George R. Marshall, Michael Rowley, Sarah Grimwood, Paul D. Leeson, Mark Peter Ridgill, Neil Roy Curtis, Janusz Jozef Kulagowski, Ian M. Mawer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1145-1150
A series of analogues of the novel diiodotyrosine derived NMDA glycine-site ligand (R)-4 was prepared in which the aryl substitution, chain length and amino acid groups were varied. The key structural features for binding are the α-amino acid functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::462c88d9948701fbd4341f4906cd036b
https://doi.org/10.1016/0960-894x(96)00187-4
https://doi.org/10.1016/0960-894x(96)00187-4
Publikováno v:
Veterinary Microbiology
The spike protein from transmissible gastroenteritis virus (TGEV) was expressed in attenuated S. typhimurium Δcya Δcrp Δasd χ3987. Three partially overlapping fragments of TGEV S gene, encoding the amino-terminal, intermediate, and carboxy-termin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a4e37a563d8b5637db94baf15ae5ce
Autor:
Janet J. Maguire, Raymond Baker, Stephen Young, Brian John Williams, Daniel F. Veber, Neil Roy Curtis, Alexander T. McKnight
Publikováno v:
Journal of Medicinal Chemistry. 36:2-10
Twenty homodetic cyclic peptides based on the C-terminal sequence of substance P were prepared (Table I) by a combination of solid-phase techniques and cyclizations using azide coupling procedures. Incorporation of dipeptide mimics based on substitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae5390c2a27c5887f4f7513db4c5ac2
https://doi.org/10.1021/jm00053a001
https://doi.org/10.1021/jm00053a001