Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Roxanne van der Sluijs"'
Autor:
Sally B. Morton, L. David Finger, Roxanne van der Sluijs, William D. Mulcrone, Michael Hodskinson, Christopher L. Millington, Christina Vanhinsbergh, Ketan J. Patel, Mark J. Dickman, Puck Knipscheer, Jane A. Grasby, David M. Williams
Publikováno v:
Journal of the American Chemical Society.
DNA interstrand cross-links (ICLs) prevent DNA replication and transcription and can lead to potentially lethal events, such as cancer or bone marrow failure. ICLs are typically repaired by proteins within the Fanconi Anemia (FA) pathway, although th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1b46b5a757461d1e3eaa694eafae56
https://pubmed.ncbi.nlm.nih.gov/36584283
https://pubmed.ncbi.nlm.nih.gov/36584283
Autor:
Roxanne van der Sluijs, Raphael Ceccaldi, Panagiotis A. Konstantinopoulos, Beatrice Rondinelli, Ewa Gogola, Jos Jonkers, Marieke van de Ven, Alexandra A. Duarte, Alan D. D'Andrea, Sven Rottenberg, Hatice Yücel
Publikováno v:
Nature Cell Biology
The emergence of resistance to poly-ADP-ribose polymerase inhibitors (PARPi) poses a threat to the treatment of BRCA1 and BRCA2 (BRCA1/2)-deficient tumours. Stabilization of stalled DNA replication forks is a recently identified PARPi-resistance mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe5aeecab17c31e96fe1c67e078f525