Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Roxanne M, Gilbride"'
Autor:
Daniel Malouli, Meenakshi Tiwary, Roxanne M. Gilbride, David W. Morrow, Colette M. Hughes, Andrea Selseth, Toni Penney, Priscila Castanha, Megan Wallace, Yulia Yeung, Morgan Midgett, Connor Williams, Jason Reed, Yun Yu, Lina Gao, Gabin Yun, Luke Treaster, Amanda Laughlin, Jeneveve Lundy, Jennifer Tisoncik-Go, Leanne S. Whitmore, Pyone P. Aye, Faith Schiro, Jason P. Dufour, Courtney R. Papen, Husam Taher, Louis J. Picker, Klaus Früh, Michael Gale, Nicholas J. Maness, Scott G. Hansen, Simon Barratt-Boyes, Douglas S. Reed, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract An influenza vaccine approach that overcomes the problem of viral sequence diversity and provides long-lived heterosubtypic protection is urgently needed to protect against pandemic influenza viruses. Here, to determine if lung-resident effe
Externí odkaz:
https://doaj.org/article/30aee6ee13914e60b17c02c57c123179
Autor:
Benjamin N. Bimber, Justine Sunshine, G. W. McElfresh, Jason S. Reed, Reese Pathak, Katherine B. Bateman, Colette M. Hughes, Roxanne M. Gilbride, Julia C. Ford, David Morrow, Jeffrey D. Lifson, Jonah B. Sacha, Scott G. Hansen, Louis J. Picker
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Simian immunodeficiency virus (SIV) vaccines based upon 68-1 Rhesus Cytomegalovirus (RhCMV) vectors show remarkable protection against pathogenic SIVmac239 challenge. Across multiple independent rhesus macaque (RM) challenge studies, nearly 60% of va
Externí odkaz:
https://doaj.org/article/e783a3dcc0a04683937ff350828c93ad
Autor:
Scott G. Hansen, Jennie L. Womack, Wilma Perez, Kimberli A. Schmidt, Emily Marshall, Ravi F. Iyer, Hillary Cleveland Rubeor, Claire E. Otero, Husam Taher, Nathan H. Vande Burgt, Richard Barfield, Kurt T. Randall, David Morrow, Colette M. Hughes, Andrea N. Selseth, Roxanne M. Gilbride, Julia C. Ford, Patrizia Caposio, Alice F. Tarantal, Cliburn Chan, Daniel Malouli, Peter A. Barry, Sallie R. Permar, Louis J. Picker, Klaus Früh
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
Rhesus cytomegalovirus–based (RhCMV-based) vaccine vectors induce immune responses that protect ~60% of rhesus macaques (RMs) from SIVmac239 challenge. This efficacy depends on induction of effector memory–based (EM-biased) CD8+ T cells recognizi
Externí odkaz:
https://doaj.org/article/2cef4c4bc58642d4a61f2fb76b14a405
Autor:
Xiao L. Chang, Gabriela M. Webb, Helen L. Wu, Justin M. Greene, Shaheed Abdulhaqq, Katherine B. Bateman, Jason S. Reed, Cleiton Pessoa, Whitney C. Weber, Nicholas Maier, Glen M. Chew, Roxanne M. Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M. Magnani, Jeremy Smedley, Benjamin N. Bimber, Nancy L. Haigwood, Scott G. Hansen, Timothy R. Brown, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
CCR5 is a co-receptor for many transmitted HIV strains. Here, the authors show that biweekly injection of the CCR5-specific antibody Leronlimab protects rhesus macaques against infection following repeated intrarectal challenges of a CCR5-tropic SHIV
Externí odkaz:
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
Autor:
Fredrik Barrenäs, Scott G Hansen, Lynn Law, Connor Driscoll, Richard R Green, Elise Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne Whitmore, Daniel Newhouse, Colette M Hughes, David Morrow, Kurt T Randall, Andrea N Selseth, Julia C Ford, Roxanne M Gilbride, Bryan E Randall, Emily Ainslie, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J Bosche, Michael K Axthelm, Yoshinori Fukazawa, George N Pavlakis, Barbara K Felber, Slim Fourati, Rafick-Pierre Sekaly, Jeffrey D Lifson, Jan Komorowski, Ewelina Kosmider, Danica Shao, Wenjun Song, Paul T Edlefsen, Louis J Picker, Michael Gale
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009278 (2021)
Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68-1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent clearance of h
Externí odkaz:
https://doaj.org/article/cd57c9263ff449bb8bd672c756c1208a
Autor:
Jeremy V. Smedley, Rachele M. Bochart, Miranda Fischer, Heidi Funderburgh, Vanessa Kelly, Hugh Crank, Kim Armantrout, Oriene Shiel, Mitchell Robertson‐LeVay, Nikki Sternberger, Brian Schmaling, Sheila Roberts, Vicki Sekiguchi, Michael Reusz, Tiah Schwartz, Kimberly A. Meyer, Gabriela Webb, Roxanne M. Gilbride, Nicholas Dambrauskas, Daniela Andrade, Matthew Wood, Caralyn Labriola, Michael Axthelm, Nina Derby, Ben Varco‐Merth, Yoshinori Fukazawa, Scott Hansen, Jonah B. Sacha, Donald L. Sodora, D. Noah Sather
Publikováno v:
Journal of Medical Primatology. 51:270-277
Identification of lymph nodes (LNs) draining a specific site or in obese macaques can be challenging.Indocyanine Green (ICG) was administered intradermal (ID), intramuscular, in the oral mucosa, or subserosal in the colon followed by Near Infrared (N
Autor:
Bruce K. Patterson, Whitney C. Weber, Gabriela M. Webb, Katherine B. Bateman, Cleiton Pessoa, Shaheed A. Abdulhaqq, Lina Gao, Benjamin N. Bimber, Jonah B. Sacha, Scott G. Hansen, Xiao L. Chang, Justin M. Greene, Kush Dhody, Scott Kelly, Nancy L. Haigwood, Rebecca Agnor, Cassandra Moats, Glen M. Chew, Roxanne M. Gilbride, Jeremy Smedley, Nicole D Burnett, Oriene Shiel, Nicholas Maier, Don Siess, Lishomwa C. Ndhlovu, Miranda Fischer, Timothy R. Brown, Diogo M. Magnani, Jason S. Reed, Travis Giobbi, Jeffrey Torgerson, Helen L. Wu, Nader Pourhassan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
In the absence of a prophylactic vaccine, the use of antiretroviral therapy (ART) as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition by uninfected individuals is a promising approach to slowing the epidemic, but its efficacy is hampered by
Autor:
Scott G. Hansen, Meaghan H. Hancock, Daniel Malouli, Emily E. Marshall, Colette M. Hughes, Kurt T. Randall, David Morrow, Julia C. Ford, Roxanne M. Gilbride, Andrea N. Selseth, Renee Espinosa Trethewy, Lindsey M. Bishop, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J. Bosche, Michael Hull, Lorna Silipino, Michael Nekorchuk, Kathleen Busman-Sahay, Jacob D. Estes, Michael K. Axthelm, Jeremy Smedley, Danica Shao, Paul T. Edlefsen, Jeffrey D. Lifson, Klaus Früh, Jay A. Nelson, Louis J. Picker
Publikováno v:
Sci Immunol
The strain 68-1 rhesus cytomegalovirus (RhCMV)–based vaccine for simian immunodeficiency virus (SIV) can stringently protect rhesus macaques (RMs) from SIV challenge by arresting viral replication early in primary infection. This vaccine elicits un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0029e764e7ae4b9f7d96198478afd222
https://europepmc.org/articles/PMC9387538/
https://europepmc.org/articles/PMC9387538/
Autor:
Hugh B. Crank, Kimberly Armantrout, Lauren D. Martin, Cassandra Moats, Kurt T. Randall, Scott G. Hansen, Theodore R. Hobbs, Tonya Swanson, Nicole D Burnett, Roxanne M. Gilbride, Aaron M. Barber-Axthelm, Jeremy Smedley
Publikováno v:
Comp Med
Nonbronchoscopic bronchoalveolar lavage (NB-BAL) is a minimally invasive diagnostic and research tool used to sample the cells of lower airways and alveoli without using a bronchoscope. Our study compared NB-BAL and bronchoscopic bronchoalveolar lava
Autor:
Patrick K Hashiguchi, Jason S. Reed, Sreya Biswas, Scott G. Hansen, Louis J. Picker, Jonah B. Sacha, Roxanne M. Gilbride, Klaus Früh, Christine Meyer, Michael K. Axthelm, Helen L. Wu, Jennie Womack, Benjamin J. Burwitz, Mandana Mansouri
Publikováno v:
The Journal of Immunology. 204:2169-2176
Currently 247 million people are living with chronic hepatitis B virus infection (CHB), and the development of novel curative treatments is urgently needed. Immunotherapy is an attractive approach to treat CHB, yet therapeutic approaches to augment t