Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Roxanne Edge"'
Autor:
Katharine K. Miller, Kazuaki Homma, Soma Sengupta, Mary Ann Cheatham, Jing Zheng, Peter Dallos, Roxanne Edge
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1803(7):796-804
Prestin is the motor protein responsible for cochlear outer hair cell (OHC) somatic electromotility. Eliminating this abundant basolateral membrane protein not only causes loss of frequency selectivity and hearing sensitivity, but also leads to OHC d
Autor:
Mary Ann Cheatham, Jian Zuo, Charles T. Anderson, Peter Dallos, Guo Guang Du, Allen F. Ryan, Jing Zheng, Roxanne Edge, K. H. Huynh
Publikováno v:
Audiology and Neurotology. 12:378-390
Studies using the prestin knockout mouse indicate that removal of the outer hair cell (OHC) motor protein is associated with loss of sensitivity, frequency selectivity and somatic electromotility. Here we provide data obtained from another prestin mo
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145428 (2015)
PLoS ONE
PLoS ONE
A knockin (KI) mouse expressing mutated prestin V499G/Y501H (499 prestin) was created to study cochlear amplification. Recordings from isolated outer hair cells (OHC) in this mutant showed vastly reduced electromotility and, as a consequence, reduced
Autor:
Roxanne Edge, Mary Ann Cheatham, Jing Zheng, Khurram Naik, Sharon Low-Zeddies, Peter Dallos, Charles T. Anderson
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(38)
A chimera is a genetic composite containing a unique mix of cells derived from more than one zygote. This mouse model allows one to learn how cells of contrasting genotype functionally interactin vivo. Here, we investigate the effect that different p
A frequency-dependent change in hearing sensitivity occurs during maturation in the basal gerbil cochlea. This change takes place during the first week after the onset of hearing. It has been argued that the mass of a given cochlear segment decreases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3023686165d72cbb80dd297130036e3
https://europepmc.org/articles/PMC2504543/
https://europepmc.org/articles/PMC2504543/
Publikováno v:
Hearing research. 145(1-2)
In order to identify hair cell specific genes, it is essential to obtain isolated hair cells in quantity. While whole-cell recordings have been made from isolated inner hair cells (IHCs) from guinea pigs, detailed methods for obtaining a fairly large
Publikováno v:
Hearing research. 124(1-2)
Our knowledge of cochlear geometry is based largely upon anatomical observations derived from fixed, dehydrated, embedded and/or sputter-coated material. We have now developed a novel preparation, the hemicochlea, where for the first time living coch
Autor:
M. Sainz, Allen F. Ryan, E. Van Eyken, Mary Ann Cheatham, Jing Zheng, Hero P. Wit, J.M. Ballesteros, Betty Kwong, Frans W. J. Albers, J. García-Valdecasas, Liesbet Ruytjens, Pim van Dijk, Peter Dallos, Antoon T. M. Willemsen, Manuel Don, Gerhard Goebel, Chiemi Tanaka, L. Van Laer, Charles T. Anderson, Guo Guang Du, Wolfgang Hiller, M. Garófano, Roxanne Edge, Jian Zuo, K. H. Huynh, G. Van Camp
Publikováno v:
Audiology and Neurotology. 12:410-411
Autor:
Manuel Don, Betty Kwong, Jing Zheng, Allen F. Ryan, E. Van Eyken, Wolfgang Hiller, J. García-Valdecasas, Pim van Dijk, Jian Zuo, Chiemi Tanaka, Guo Guang Du, K. H. Huynh, Peter Dallos, Frans W. J. Albers, G. Van Camp, Antoon T. M. Willemsen, Gerhard Goebel, M. Sainz, Liesbet Ruytjens, M. Garófano, Mary Ann Cheatham, Hero P. Wit, L. Van Laer, Charles T. Anderson, Roxanne Edge, J.M. Ballesteros
Publikováno v:
Audiology and Neurotology. 12:408-409
Publikováno v:
Journal of neurophysiology. 79(5)
Richter, Claus-Peter, Burt N. Evans, Roxanne Edge, and Peter Dallos. Basilar membrane vibration in the gerbil hemicochlea. J. Neurophysiol. 79: 2255–2264, 1998. Excised gerbil cochleae were cut along the mid-modiolar plane (hemicochlea). Along one-