Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Roxanne Dutia"'
Autor:
Roxanne Dutia, Andrea J Kim, Matthew Modes, Robert Rothlein, Jane M Shen, Ye Edward Tian, Jumana Ihbais, Sam F Victory, Carmen Valcarce, Sharon L Wardlaw
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65317 (2013)
Activation of brain melanocortin-4 receptors (MC4-R) by α-melanocyte-stimulating hormone (MSH) or inhibition by agouti-related protein (AgRP) regulates food intake and energy expenditure and can modulate neuroendocrine responses to changes in energy
Externí odkaz:
https://doaj.org/article/e44e13271cb540bb9dde7b5507c314ba
Autor:
Blandine Laferrère, Ankit Shah, Victoria Mark, Nandini Nair, Malini Prasad, Chanel Ligon, Roxanne Dutia
Publikováno v:
Diabetes Care
OBJECTIVE The role of the gut in diabetes remission after Roux-en-Y gastric bypass (RYGB) is incompletely understood. We assessed the temporal change in insulin secretory capacity after RYGB, using oral and intravenous (IV) glucose, in individuals wi
Autor:
Michael Ahlers, Roxanne Dutia, Martin J. Blaser, Nan Shen, Blandine Laferrère, Kapila Patel, Assumpta Caixàs, Zhan Gao, Jose C. Clemente
Publikováno v:
Surg Obes Relat Dis
Background Some of the metabolic effects of bariatric surgery may be mediated by the gut microbiome. Objectives To study the effect of bariatric surgery on changes to gut microbiota composition and bacterial pathways, and their relation to metabolic
Autor:
Sarah Stano, Kiarra Levesque, Betsy L. Rojas, Roxanne Dutia, Marlena M. Holter, James McGinty, Esmeralda Pierini, Michael Ahlers, Ankit Shah, Scott Belsley, Blandine Laferrère
Publikováno v:
Diabetes, Obesity and Metabolism. 20:1018-1023
The present study was a 4-week randomized trial to assess the efficacy and safety of sitagliptin, a dipeptidyl-peptidase-4 inhibitor, in persistent or recurring type 2 diabetes after Roux-en-Y gastric bypass surgery (RYGB). Participants (n = 32) comp
Autor:
James McGinty, Ankit Shah, Michael Ahlers, Roxanne Dutia, Kiarra Levesque, Koji Park, Kapila Patel, Marlena M. Holter, Eugenius J. Harvey, Blandine Laferrère, Fatima Alam, Esmeralda Pierini, Betsy L. Rojas, Scott Belsley, Ninan Koshy, Victoria Mark
Publikováno v:
Diabetes. 67
β-cell glucose sensitivity (BCGS) improves after gastric bypass (RYGB) in individuals in diabetes (DM2) remission. We sought to assess BCGS (pmol/kg/min/mM) after an oral glucose test (OGT) and an IV graded glucose infusion (GGI) in subjects with an
Autor:
Fatima Rimawi, Bruce Levin, Victoria Mark, Blandine Laferrère, Ankit Shah, James McGinty, Roxanne Dutia, Marlena M. Holter
Publikováno v:
Diabetes care. 42(2)
OBJECTIVE Hepatic insulin clearance is a significant regulator of glucose homestasis. We hypothesized that the improvement in insulin clearance rates (ICRs) under fasting conditions and in response to oral and intravenous (IV) glucose would improve s
Autor:
Peter Homel, Katrina Brakoniecki, Blandine Laferrère, André C. Carpentier, Phoebe Bunker, Furcy Paultre, James McGinty, Roxanne Dutia
Publikováno v:
Diabetes
The mechanisms responsible for the remarkable remission of type 2 diabetes after Roux-en-Y gastric bypass (RYGBP) are still puzzling. To elucidate the role of the gut, we compared β-cell function assessed during an oral glucose tolerance test (OGTT)
Publikováno v:
American Journal of Obstetrics and Gynecology. 218:S230-S231
Autor:
Ronald L. Prigeon, James McGinty, Peter Homel, Roxanne Dutia, Sarah Stano, Marlena M. Holter, Daniel J. Rosen, Scott Belsley, Blandine Laferrère, Christine J. Ren
Publikováno v:
Diabetes Care
OBJECTIVE The superior effect of Roux-en-Y gastric bypass (RYGB) on glucose control compared with laparoscopic adjustable gastric banding (LAGB) is confounded by the greater weight loss after RYGB. We therefore examined the effect of these two surger
Publikováno v:
Endocrinology. 153:4246-4255
Proopiomelanocortin (POMC) is posttranslationally processed to several peptides including α-MSH, a primary regulator of energy balance that inhibits food intake and stimulates energy expenditure. However, another POMC-derived peptide, β-endorphin (