Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Roxanne A. Vaughan"'
Autor:
Madhur Shetty, Danielle E. Bolland, Joshua Morrell, Bryon D. Grove, James D. Foster, Roxanne A. Vaughan
Publikováno v:
Current Research in Physiology, Vol 6, Iss , Pp 100106- (2023)
The primary regulator of dopamine availability in the brain is the dopamine transporter (DAT), a plasma membrane protein that drives reuptake of released dopamine from the extracellular space into the presynaptic neuron. DAT activity is regulated by
Externí odkaz:
https://doaj.org/article/2cd3ce10da6d4b5ab18d57d3cadadfb7
Autor:
Adele Stewart, Felix P. Mayer, Raajaram Gowrishankar, Gwynne L. Davis, Lorena B. Areal, Paul J. Gresch, Rania M. Katamish, Rodeania Peart, Samantha E. Stilley, Keeley Spiess, Maximilian J. Rabil, Faakhira A. Diljohn, Angelica E. Wiggins, Roxanne A. Vaughan, Maureen K. Hahn, Randy D. Blakely
Publikováno v:
Molecular Psychiatry. 27:4869-4880
Publikováno v:
Journal of Neurochemistry. 152:623-626
The dorsal striatum coordinates input-output processing of numerous functions including those related to motor activity, motivation, and learning. Considerable anatomical and biochemical heterogeneity across striatal subregions has long been known to
Autor:
Adele, Stewart, Felix P, Mayer, Raajaram, Gowrishankar, Gwynne L, Davis, Lorena B, Areal, Paul J, Gresch, Rania M, Katamish, Rodeania, Peart, Samantha E, Stilley, Keeley, Spiess, Maximilian J, Rabil, Faakhira A, Diljohn, Angelica E, Wiggins, Roxanne A, Vaughan, Maureen K, Hahn, Randy D, Blakely
Publikováno v:
Molecular psychiatry. 27(12)
Virtually all neuropsychiatric disorders display sex differences in prevalence, age of onset, and/or clinical symptomology. Although altered dopamine (DA) signaling is a feature of many of these disorders, sex-dependent mechanisms uniquely responsive
Autor:
Maureen K. Hahn, Gwynne L. Davis, Samantha E. Stilley, Keeley Spiess, Adele Stewart, Roxanne A. Vaughan, Lorena B. Areal, Faakhira A. Diljohn, Randy D. Blakely, Raajaram Gowrishankar, Angelica E. Wiggins, Maximilian J. Rabil, Rania M. Katamish, Paul J. Gresch, Rodeania Peart, Felix P. Mayer
Virtually all neuropsychiatric disorders display sex differences in prevalence, age of onset, and/or clinical symptomology. In sex-biased disorders, one sex is often suggested to harbor protective mechanisms, rendering them resilient to genetic and/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::765de5c42f094a78d6218f82387e92df
https://doi.org/10.1101/2021.11.02.466932
https://doi.org/10.1101/2021.11.02.466932
Autor:
Daniel J. Stanislowski, Amy E. Moritz, James D. Foster, Danielle E. Bolland, Roxanne A. Vaughan
Publikováno v:
ACS Chem Neurosci
The dopamine transporter (DAT) is a plasma membrane protein that mediates the reuptake of extracellular dopamine (DA) and controls the spatiotemporal dynamics of dopaminergic neurotransmission. The transporter is subject to fine control that tailors
Autor:
Seok Heo, James D. Foster, Garret H. Larson, Lisa Konrad, Fatma Asli Erdem, Roxanne A. Vaughan, Marion Holy, Madhur Shetty, Gert Lubec, Harald H. Sitte, Mirja Kastein, Jae-Won Yang, Kathrin Jäntsch
Publikováno v:
Journal of Biological Chemistry. 294:3419-3431
Several protein kinases, including protein kinase C, Ca(2+)/calmodulin-dependent protein kinase II, and extracellular signal–regulated kinase, play key roles in the regulation of dopamine transporter (DAT) functions. These functions include surface
Autor:
Akula Bala Pramod, John R. Lever, Danielle Krout, L. Keith Henry, Michael J. Tomlinson, Roxanne A. Vaughan, Amy Hauck Newman
Publikováno v:
Neurochemistry International. 123:34-45
The dopamine transporter (DAT) is a neuronal membrane protein that is responsible for reuptake of dopamine (DA) from the synapse and functions as a major determinant in control of DA neurotransmission. Cocaine and many psychostimulant drugs bind to D
Publikováno v:
Neurochemistry International. 123:13-21
The dopamine transporter (DAT) plays a critical role in dopamine (DA) homeostasis by clearing transmitter from the extraneuronal space after vesicular release. DAT serves as a site of action for a variety of addictive and therapeutic reuptake inhibit
Autor:
Nicole Speed, Christine Saunders, Adeola R Davis, W Anthony Owens, Heinrich J G Matthies, Sanaz Saadat, Jack P Kennedy, Roxanne A Vaughan, Rachael L Neve, Craig W Lindsley, Scott J Russo, Lynette C Daws, Kevin D Niswender, Aurelio Galli
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25169 (2011)
BackgroundThe prevalence of obesity has increased dramatically worldwide. The obesity epidemic begs for novel concepts and therapeutic targets that cohesively address "food-abuse" disorders. We demonstrate a molecular link between impairment of a cen
Externí odkaz:
https://doaj.org/article/05ed995f3cb24c789dbad3cf779f0c17