Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Roxanna Barnaby"'
Autor:
Katja Koeppen, Roxanna Barnaby, Angelyca A Jackson, Scott A Gerber, Deborah A Hogan, Bruce A Stanton
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211290 (2019)
Tobramycin is commonly used to treat Pseudomonas aeruginosa lung infections in patients with Cystic Fibrosis (CF). Tobramycin treatment leads to increased lung function and fewer clinical exacerbations in CF patients, and modestly reduces the density
Externí odkaz:
https://doaj.org/article/c5098f07e4d74c908f86a2dfcec3faf2
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127742 (2015)
P. aeruginosa is an opportunistic pathogen that chronically infects the lungs of 85% of adult patients with Cystic Fibrosis (CF). Previously, we demonstrated that P. aeruginosa reduced wt-CFTR Cl secretion by airway epithelial cells. Recently, a new
Externí odkaz:
https://doaj.org/article/1157a6f42c50499aa48b52ab0e9c7266
Autor:
Emily G Notch, Britton C Goodale, Roxanna Barnaby, Bonita Coutermarsh, Brent Berwin, Vivien F Taylor, Brian P Jackson, Bruce A Stanton
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142392 (2015)
Arsenic is the number one contaminant of concern with regard to human health according to the World Health Organization. Epidemiological studies on Asian and South American populations have linked arsenic exposure with an increased incidence of lung
Externí odkaz:
https://doaj.org/article/8ed1600c299b42958253dc4f024f16e8
Autor:
Katja Koeppen, Thomas H. Hampton, Roxanna Barnaby, Carolyn Roche, Scott A. Gerber, Young Ah Goo, Byoung-Kyu Cho, Danielle M. Vermilyea, Deborah A. Hogan, Bruce A. Stanton
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology.
Lung infections caused by antibiotic resistant strains of Pseudomonas aeruginosa are difficult to eradicate in immunocompromised hosts such as those with cystic fibrosis. We previously demonstrated that extracellular vesicles (EVs) secreted by primar
Autor:
Amanda B. Nymon, Zhongyou Li, Alix Ashare, Roxanna Barnaby, Thomas H. Hampton, Bruce A Stanton, Katja Koeppen
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Mutations in CFTR alter macrophage responses, for example, by reducing their ability to phagocytose and kill bacteria. Altered macrophage responses may facilitate bacterial infection and inflammation in the lungs, contributing to morbidity and mortal
Autor:
Bryan A. Garcia, Melissa S. McDaniel, Allister J. Loughran, J. Dixon Johns, Vidya Narayanaswamy, Courtney Fernandez Petty, Susan E. Birket, Shenda M. Baker, Roxanna Barnaby, Bruce A. Stanton, Jeremy B. Foote, Steven M. Rowe, W. Edward Swords
Publikováno v:
Microbiology. 168
Pseudomonas aeruginosa is a common opportunistic pathogen that can cause chronic infections in multiple disease states, including respiratory infections in patients with cystic fibrosis (CF) and non-CF bronchiectasis. Like many opportunists, P. aerug
Autor:
Zhongyou Li, Katja Koeppen, Bruce A. Stanton, Carey D. Nadell, Fred W. Kolling, Swetha Kasetty, Laura Bashor, Amanda E Liefeld, Deborah A. Hogan, Thomas H. Hampton, Scott A. Gerber, Amanda B. Nymon, Roxanna Barnaby, Ian S LaCroix
Publikováno v:
Proc Natl Acad Sci U S A
Pseudomonas aeruginosa is an opportunistic pathogen that forms antibiotic-resistant biofilms, which facilitate chronic infections in immunocompromised hosts. We have previously shown that P. aeruginosa secretes outer-membrane vesicles that deliver a
Autor:
Bruce A. Stanton, Mark A. Cervinski, Moemen Abdalla, John A. Dessaint, Carol S. Ringelberg, Roxanna Barnaby, David A. Armstrong, Haley F. Hazlett, Alix Ashare, Louisa Howard
Publikováno v:
The Journal of Molecular Diagnostics. 20:565-571
There are currently no standardized protocols for pre-analytical handling of urine to best preserve small RNA for miRNA profiling studies. miRNA is an attractive candidate as a potential biomarker because of the high level of stability in body fluids
Autor:
Brent Berwin, Alix Ashare, Amanda B. Nymon, Thomas H. Hampton, Katja Koeppen, Roxanna Barnaby, Bruce A. Stanton
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 314:L432-L438
Cystic fibrosis (CF), the most common lethal genetic disease in Caucasians, is characterized by chronic bacterial lung infection and excessive inflammation, which lead to progressive loss of lung function and premature death. Although ivacaftor (VX-7
Publikováno v:
Environmental Research. 158:610-615
Arsenic contamination of drinking water is a serious threat to the health of hundreds of millions of people worldwide. In the United States ~3 million individuals drink well water that contains arsenic levels above the Environmental Protection Agency