Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Roxann Hétu-Arbour"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Regulation of hematopoietic stem cell (HSC) self-renewal and differentiation is essential for their maintenance, and HSC polarity has been shown to play an important role in this regulation. Vangl2, a key component of the Wnt/polarity pathway, is exp
Externí odkaz:
https://doaj.org/article/abc28f50f5134d6da267480404ffae9f
Autor:
Krista M. Heinonen, Belma Melda Abidin, Roxann Hétu-Arbour, Edward Owusu Kwarteng, Mouna Tlili, Fabio Luiz Bandeira Ferreira
Publikováno v:
Stem Cells. 39:1207-1220
Although intracellular Wnt signaling pathways need to be tightly regulated to promote hematopoietic stem cell self-renewal, the source and identity of important Wnt ligands in the bone marrow is still largely unknown. The noncanonical ligand Wnt4 is
Publikováno v:
Leukemia Stem Cells ISBN: 9781071608098
Hematopoietic stem cells have the ability to produce all blood cells. When hematological malignancies occur, transplant of compatible blood or bone marrow cells from a healthy donor to the patient is an efficient solution to restore normal hematopoie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f305bef41fa2e841cb523134ec91960f
https://doi.org/10.1007/978-1-0716-0810-4_12
https://doi.org/10.1007/978-1-0716-0810-4_12
Publikováno v:
Journal of leukocyte biology. 103(3)
The switch from fetal to adult hematopoietic stem/progenitor cells (HSPCs) is associated with profound changes in several genetic programs. Although HSPC ageing corresponds to alterations in Wnt signaling, relatively little is known about the relativ