Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Roxane Ridolfo"'
Autor:
Vijayabhaskarreddy Junnuthula, Amir Sadeghi Boroujeni, Shoupeng Cao, Shirin Tavakoli, Roxane Ridolfo, Elisa Toropainen, Marika Ruponen, Jan C. M. van Hest, Arto Urtti
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 445 (2021)
Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers. Intravitreal injections are widely used, but the intervals between invasive in
Externí odkaz:
https://doaj.org/article/5b4451b8b75c415c89a4c0dc5880d5fe
Autor:
Roxane Ridolfo, Jan C. M. van Hest, Shirin Tavakoli, Vijayabhaskarreddy Junnuthula, David S. Williams, Arto Urtti
Publikováno v:
Biomacromolecules, 22(1), 126-133. American Chemical Society
Biomacromolecules
Biomacromolecules
Nanoparticle morphology (size, shape, and composition) and surface chemistry are the determining factors underpinning the efficacy of such materials in therapeutic applications. The size, shape, and surface chemistry of a nanoparticle can strongly in
Publikováno v:
Polymer Chemistry, 11(16), 2775-2780. Royal Society of Chemistry
Polymer Chemistry
Polymer Chemistry
Polymeric vesicles (polymersomes) are an important class of nanoparticles for various biomedical applications. Their interaction with biological systems is strongly dependent on their topological features such as size, shape and surface charge. We ha
Autor:
Amir Sadeghi, Marika Ruponen, Jooseppi Puranen, Shoupeng Cao, Roxane Ridolfo, Shirin Tavakoli, Elisa Toropainen, Tatu Lajunen, Veli-Pekka Ranta, Jan van Hest, Arto Urtti
Publikováno v:
International Journal of Pharmaceutics, 621:121800. Elsevier
In this study, the intravitreal pharmacokinetics of nanomaterials were investigated in vivo in rats and rabbits. Impact of particle size and shape (spherical, longitudinal) on ocular particle distribution and elimination was investigated with fundus
Publikováno v:
Journal of Controlled Release
Journal of Controlled Release, 259(10 august 2016), 29-39. Elsevier
Journal of Controlled Release, 259(10 august 2016), 29-39. Elsevier
Amidst the wealth of information that the past few decades of nanomedical research has given us there is one design principle that has emerged as being key for the success of delivery vectors: particle morphology. This review seeks to unpack the vari
Autor:
Benjamin C Ede, David S. Williams, Roxane Ridolfo, Jan C. M. van Hest, Paraskevi Diamanti, Adam W. Perriman, Allison Blair, Paul B. White
Publikováno v:
Small, 14(32):1703774. Wiley-VCH Verlag
Small, 14, 1-10
Small, 14, 32, pp. 1-10
Small
Ridolfo, R, Ede, B C, Diamanti, P, White, P B, Perriman, A W, van Hest, J C M, Blair, A & Williams, D S 2018, ' Biodegradable, Drug-Loaded Nanovectors via Direct Hydration as a New Platform for Cancer Therapeutics ', Small, vol. 14, no. 32, 1703774 . https://doi.org/10.1002/smll.201703774
Small, 14, 1-10
Small, 14, 32, pp. 1-10
Small
Ridolfo, R, Ede, B C, Diamanti, P, White, P B, Perriman, A W, van Hest, J C M, Blair, A & Williams, D S 2018, ' Biodegradable, Drug-Loaded Nanovectors via Direct Hydration as a New Platform for Cancer Therapeutics ', Small, vol. 14, no. 32, 1703774 . https://doi.org/10.1002/smll.201703774
The stabilization and transport of low-solubility drugs, by encapsulation in nanoscopic delivery vectors (nanovectors), is a key paradigm in nanomedicine. However, the problems of carrier toxicity, specificity, and producibility create a bottleneck i
Autor:
'Roxane Ridolfo
Publikováno v:
David S. Williams