Combined genomic-proteomic approach in the identification of Campylobacter coli amoxicillin-clavulanic acid resistance mechanism in clinical isolates

Autor: Francis Deforet, Quentin Jehanne, Lucie Bénéjat, Johanna Aptel, Roxane Prat, Chloé Desbiolles, Astrid Ducournau, Marine Jauvain, Richard Bonnet, François Vandenesch, Jérôme Lemoine, Philippe Lehours

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

IntroductionAminopenicillins resistance among Campylobacter jejuni and Campylobacter coli strains is associated with a single mutation in the promoting region of a chromosomal beta-lactamase blaOXA61, allowing its expression. Clavulanic acid is used

Externí odkaz: https://doaj.org/article/d13cb581498f4477a21c4234fbfaf508

A single and rapid SWATH DIA proteomic analysis for concomitant identification and antibiotic resistance profiling of micro-organisms from positive blood cultures

Autor: Iulia Macavei, Eva Peyrache, Maud Gregson, Romain Carrière, Roxane Prat, Chloé Desbiolles, Tiphaine Cecchini, Francis Deforet, Aour Dufour, Pierre L., Delphine Arquier, Olivier Dauwalder, François Vandenesch, Jérôme Lemoine

Publikováno v: 62nd LBMSDG Meeting, The Francis Crick Institute
62nd LBMSDG Meeting, The Francis Crick Institute, London Biological Mass Spectrometry Discussion Group; SCIEX, Dec 2022, London (UK), United Kingdom
HAL

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::24e69775c6cf4202bf86bf7c3ad5192d
https://hal.science/hal-04000402

Fast and accurate identification and antibiotic resistance profiling of micro-organisms in blood cultures by SWATH-MS proteomics

Autor: Iulia Macavei, Eva Peyrache, Maud Gregson, Romain Carrière, Roxane Prat, Chloé Desbiolles, Aour Dufour, Pierre L., Francis Deforet, Tiphaine Cecchini, Olivier Dauwalder, François Vandenesch, Jérôme Lemoine

Publikováno v: HAL
SCIEX Breakfast Seminar, The pursuit of new biomarkers, 70th Conference on Mass Spectrometry and Allied Topics
SCIEX Breakfast Seminar, The pursuit of new biomarkers, 70th Conference on Mass Spectrometry and Allied Topics, American Society for Mass Spectrometry; SCIEX, Jun 2022, Minneapolis (Minnesota), United States
70th Conference on Mass Spectrometry and Allied Topics
70th Conference on Mass Spectrometry and Allied Topics, American Society for Mass Spectrometry, Jun 2022, Minneapolis (Minnesota), United States
Advances in Proteomics & Metabolomics 2022
Advances in Proteomics & Metabolomics 2022, Technology Networks; SCIEX, Sep 2022, Online webinar, United Kingdom

International audience; IntroductionToday, approximately 1.3 million people die each year worldwide from bacterial antimicrobial resistance (AMR). AMR is of great concern in the context of bloodstream infections (BSIs) when it evolves into sepsis. If

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a26152cfcc69e36d04cff0050f04745
https://hal.science/hal-04001057