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Akademický článek

Facial palsy after administration of immune checkpoint inhibitors: case report, literature review and clinical care management

Autor: Essia Mezni, Giovanni Corazza, Roxane Mari, Stephanie Coze, Nathalie Charrier, Brice Chanez, Anne Sophie Chretien, Philippe Rochigneux

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Neurological immune-related adverse events (irAEs) due to immune checkpoint inhibitors (ICI) are rare complications of immunotherapy, particularly dreadful for patients and clinical teams. Indeed, neurological irAEs are potentially severe and their d

Externí odkaz: https://doaj.org/article/856b370e5e3941128a2eb97928911381

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Akademický článek

Dysthyroidism during immune checkpoint inhibitors is associated with improved overall survival in adult cancers: data mining of 1385 electronic patient records

Autor: Anne Madroszyk, Gwenaelle Gravis, Laurent Gorvel, Daniel Olive, Christophe Zemmour, Philippe Rochigneux, Anthony Gonçalves, Mathilde Beaufils, Vincent Amodru, Manuel Tejeda, Jean Marie Boher, Brice Chanez, Anne Sophie Chrétien, Damien Bruyat, Roxane Mari, Thomas Cuny, Aaron E Lisberg, Louis Tassy, Frederic Castinetti

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)

Background Dysthyroidism (DT) is a common toxicity of immune checkpoint inhibitors (ICIs) and prior work suggests that dysthyroidism (DT) might be associated with ICI efficacy.Patients and methods ConSoRe, a new generation data mining solution, was u

Externí odkaz: https://doaj.org/article/b975d57f3e8b46958dd86ac07ec93343

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Akademický článek

Durable disease control and refractory bullous pemphigoid after immune checkpoint inhibitor discontinuation in metastatic renal cell carcinoma: A case report

Autor: Roxane Mari, Mathilde Guerin, Cécile Vicier, Jochen Walz, Nathalie Bonnet, Géraldine Pignot, Gwenaelle Gravis

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

BackgroundImmune checkpoint inhibitors deeply modified metastatic renal cell carcinoma’s management, and confront us to adverse events that we were not used to with conventional anti-cancer therapies. We report the case of a patient who received ni

Externí odkaz: https://doaj.org/article/a97d1be667554866b1ad2ae0a550489b

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Apports de l’ADN tumoral circulant dans la compréhension et la prise en charge des carcinomes d’origine gynécologique

Autor: Renaud Sabatier, Roxane Mari, Eric Lambaudie, Magali Provansal

Publikováno v: Bulletin du Cancer. 106:237-252

Resume Les cancers gynecologiques representent des pathologies frequentes, avec plus de 16 000 cas par an en France pour 6500 deces. Peu de modifications des methodes diagnostiques, des outils pronostiques, et des prises en charge therapeutiques ont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::360886b60b4e519bcc92d23403cdfdbf
https://doi.org/10.1016/j.bulcan.2018.11.018

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Circulating tumor DNA as a noninvasive marker of resectability in ovarian carcinomas

Autor: Pierre-Emmanuel Colombo, Magali Provansal, Christophe Pomel, Nadine Carbuccia, Renaud Sabatier, Fabrice Narducci, Guillaume Blache, Maria-Antonietta Cappiello, Eric Lambaudie, Séverine Garnier, Roxane Mari, François Bertucci, Daniel Birnbaum, Frédérique Rousseau, Arnaud Guille

Publikováno v: Journal of Clinical Oncology
Journal of Clinical Oncology, 2021, 39 (15_suppl), pp.5548-5548. ⟨10.1200/JCO.2021.39.15_suppl.5548⟩

5548 Background: Ovarian cancer is the leading cause of death by gynecological cancer. Complete surgery remains one of the main prognostic factors. Laparoscopic exploration is mandatory to assess surgical resectability at diagnosis or after neoadjuva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc1c21bf28a5287071b49304b2960f0
https://hal.science/hal-03622754

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Double neoplasia: squamous cell carcinoma of the esophagus and gastric lymphoma on myasthenia gravis

Autor: Sylvie Cailleres, Alina Zamfir, Thierry Allegre, Roxane Mari, Crescent Cossou-Gbeto, Abdelaziz Chaib, Régis Costello, Sophie Nahon

Publikováno v: Hématologie. 23:191-194

IntroductionLa relation entre la lymphogenese et l’auto-immunite est actuellement bien decrite dans la litterature, mais il existe tres peu de donnees associant la survenue d’un cancer solide sur un terrain auto-immun.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22eade4142291907bc875a5dfab6c5e1
https://doi.org/10.1684/hma.2017.1247

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Lethal toxicities after capecitabine intake in a previously 5-FU-treated patient: why dose matters with dihydropryimidine dehydrogenase deficiency

Autor: L'Houcine Ouafik, Crescent C Gbeto, Catherine Roche, Bruno Lacarelle, Sylvie Quaranta, Thierry Allegre, Sophie Nahon, Roxane Mari, Raphaelle Fanciullino, Caroline Solas, Joseph Ciccolini

Publikováno v: Pharmacogenomics
Pharmacogenomics, Future Medicine, 2019, 20 (13), pp.931-938. ⟨10.2217/pgs-2019-0028⟩
Pharmacogenomics, 2019, 20 (13), pp.931-938. ⟨10.2217/pgs-2019-0028⟩

Dihydropryimidine dehydrogenase (DPD) deficiency is a pharmacogenetic syndrome associated with severe or lethal toxicities with oral capecitabine. Usually, patients with history of 5-FU-based therapy with no signs for life-threatening toxicities are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80ad7d0eee8b7de3adb5b0b21c92db8
https://pubmed.ncbi.nlm.nih.gov/31486738

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Liquid Biopsies for Ovarian Carcinoma: How Blood Tests May Improve the Clinical Management of a Deadly Disease

Autor: Daniel Birnbaum, Emilie Mamessier, Eric Lambaudie, Magali Provansal, Renaud Sabatier, François Bertucci, Roxane Mari

Publikováno v: Cancers
Cancers, 2019, 11 (6), pp.774. ⟨10.3390/cancers11060774⟩
Cancers, MDPI, 2019, 11 (6), pp.774. ⟨10.3390/cancers11060774⟩
Cancers, Vol 11, Iss 6, p 774 (2019)

Ovarian cancers (OvC) are frequent, with more than 22,000 new cases each year for 14,000 deaths in the United States. Except for patients with BRCA1 or BRCA2 mutations, diagnostic methods, prognostic tools, and therapeutic strategies have not much im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468ac25f880e39cc602bc779d29379da
https://hal.science/hal-02152656/file/cancers-11-00774.pdf

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Akademický článek

SARS-CoV-2 Rapid Antigen Test Based on a New Anti-Nucleocapsid Protein Monoclonal Antibody: Development and Real-Time Validation

Publikováno v: Microorganisms, Vol 11, Iss 10, p 2422 (2023)

SARS-CoV-2 diagnostic tests have become an important tool for pandemic control. Among the alternatives for COVID-19 diagnosis, antigen rapid diagnostic tests (Ag-RDT) are very convenient and widely used. However, as SARS-CoV-2 variants may continuous

Externí odkaz: https://doaj.org/article/9d2b5f4abaf046d7a458a65c8a0c962b

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Akademický článek

Human microbiota modulation via QseC sensor kinase mediated in the Escherichia coli O104:H4 outbreak strain infection in microbiome model

Autor: Tamara Renata Machado Ribeiro, Mateus Kawata Salgaço, Maria Angela Tallarico Adorno, Miriam Aparecida da Silva, Roxane Maria Fontes Piazza, Katia Sivieri, Cristiano Gallina Moreira

Publikováno v: BMC Microbiology, Vol 21, Iss 1, Pp 1-14 (2021)

Abstract Background The intestinal microbiota plays a crucial role in human health, adjusting its composition and the microbial metabolites protects the gut against invading microorganisms. Enteroaggregative E. coli (EAEC) is an important diarrheagen

Externí odkaz: https://doaj.org/article/f2343c7cdbc647b7b308b9e9141de178

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