Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Roxane Lussier"'
Autor:
Anfal Al-Mass, Pegah Poursharifi, Marie-Line Peyot, Roxane Lussier, Isabelle Chenier, Yat Hei Leung, Anindya Ghosh, Abel Oppong, Elite Possik, Yves Mugabo, Rasheed Ahmad, Robert Sladek, S.R. Murthy Madiraju, Fahd Al-Mulla, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101609- (2022)
Objective: Glycerol-3-phosphate (Gro3P) phosphatase (G3PP) hydrolyzes Gro3P to glycerol that exits the cell, thereby operating a “glycerol shunt”, a metabolic pathway that we identified recently in mammalian cells. We have investigated the role o
Externí odkaz:
https://doaj.org/article/ef4e4aa106094673b2a836cb280c8599
Autor:
Anfal Al-Mass, Pegah Poursharifi, Marie-Line Peyot, Roxane Lussier, Emily J. Levens, Julian Guida, Yves Mugabo, Elite Possik, Rasheed Ahmad, Fahd Al-Mulla, Robert Sladek, S.R.Murthy Madiraju, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101471- (2022)
Objective: The recently identified glycerol-3-phosphate (Gro3P) phosphatase (G3PP) in mammalian cells, encoded by the PGP gene, was shown to regulate glucose, lipid and energy metabolism by hydrolyzing Gro3P and to control glucose-stimulated insulin
Externí odkaz:
https://doaj.org/article/a0ad8776085242cfa158276b9c6297e7
Autor:
Pegah Poursharifi, Camille Attané, Yves Mugabo, Anfal Al-Mass, Anindya Ghosh, Clémence Schmitt, Shangang Zhao, Julian Guida, Roxane Lussier, Heidi Erb, Isabelle Chenier, Marie-Line Peyot, Erik Joly, Christophe Noll, André C. Carpentier, S.R. Murthy Madiraju, Marc Prentki
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Enhanced energy expenditure in brown (BAT) and white adipose tissues (WAT) can be therapeutic against metabolic diseases. We examined the thermogenic role of adipose α/β-hydrolase domain 6 (ABHD6), which hydrolyzes monoacylglycerol (MAG), by employ
Externí odkaz:
https://doaj.org/article/e11e5cce8e0b4e328113e9c46cedfd1c
Autor:
Émilie Pepin, Anfal Al-Mass, Camille Attané, Kezhuo Zhang, Julien Lamontagne, Roxane Lussier, S R Murthy Madiraju, Erik Joly, Neil B Ruderman, Robert Sladek, Marc Prentki, Marie-Line Peyot
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153017 (2016)
Diet induced obese (DIO) mice can be stratified according to their weight gain in response to high fat diet as low responders (LDR) and high responders (HDR). This allows the study of β-cell failure and the transitions to prediabetes (LDR) and early
Externí odkaz:
https://doaj.org/article/a816a82e402c4a1b82063292ec35e8b2
Autor:
Camille Attané, Marie-Line Peyot, Roxane Lussier, Dongwei Zhang, Erik Joly, S R Murthy Madiraju, Marc Prentki
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159165 (2016)
Many metabolic studies employ tissue-specific gene knockout mice, which requires breeding of floxed gene mice, available mostly on C57BL/6N (NN) genetic background, with cre or Flp recombinase-expressing mice, available on C57BL/6J (JJ) background, r
Externí odkaz:
https://doaj.org/article/20f8b6bde0fb4134a26ff3d93c8a4c6e
Autor:
Marc Prentki, Roxane Lussier, Anfal Al-Mass, Emily Levens, Marie-Line Peyot, Yves Mugabo, Heidi Erb, S.R. Murthy Madiraju, Pegah Poursharifi, Elite Possik, Julian Guida, Erik Joly, Robert Sladek
Publikováno v:
The FASEB Journal. 35
Autor:
Anfal Al-Mass, Shangang Zhao, Camille Attané, Marie-Line Peyot, Anindya Ghosh, Julian Guida, Pegah Poursharifi, Isabelle Chenier, André C. Carpentier, Marc Prentki, Heidi Erb, S.R. Murthy Madiraju, Clémence Schmitt, Erik Joly, Yves Mugabo, Roxane Lussier, Christophe Noll
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
JCI Insight
JCI Insight
Enhanced energy expenditure in brown (BAT) and white adipose tissues (WAT) can be therapeutic against metabolic diseases. We examined the thermogenic role of adipose α/β-hydrolase domain 6 (ABHD6), which hydrolyzes monoacylglycerol (MAG), by employ
Autor:
Marie-Line Peyot, Nabil G. Seidah, Anna Roubtsova, Roxane Lussier, Annik Prat, Ann Chamberland, S.R. Murthy Madiraju, Marc Prentki, Rachid Essalmani
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1866:158968
Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in cholesterol homeostasis by promoting the degradation of the LDL receptor (LDLR). PCSK9 loss-of-function mutations are associated with increased fasting plasma glucose le
Autor:
Camille Attané, Robert Sladek, Julien Lamontagne, S.R. Murthy Madiraju, Erik Joly, Roxane Lussier, Kezhuo Zhang, Anfal Al-Mass, Marc Prentki, Marie-Line Peyot, Émilie Pepin, Neil B. Ruderman
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153017 (2016)
PLoS ONE
PLoS ONE
Diet induced obese (DIO) mice can be stratified according to their weight gain in response to high fat diet as low responders (LDR) and high responders (HDR). This allows the study of β-cell failure and the transitions to prediabetes (LDR) and early
Autor:
Thomas L. Jetton, Roxane Lussier, Marc Prentki, Erik Joly, Émilie Pepin, Marie-Line Peyot, Martin G. Latour, S.R. Murthy Madiraju, Bader Zarrouki, Julien Lamontagne, Marco Pineda
Publikováno v:
Diabetes
OBJECTIVE C57Bl/6 mice develop obesity and mild hyperglycemia when fed a high-fat diet (HFD). Although diet-induced obesity (DIO) is a widely studied model of type 2 diabetes, little is known about β-cell failure in these mice. RESEARCH DESIGN AND M