Výsledky vyhledávání - "Roxana Valeria Alasino"

Akademický článek

LDL-conjugated to GM1 micelles incorporating anticancer drugs to improve tumor cell uptake

Autor: Ariel Gustavo Garro, Roxana Valeria Alasino, Victoria Leonhard, Valeria Heredia, Dante Miguel Beltramo

Publikováno v: Nanomedicine Journal, Vol 8, Iss 2, Pp 106-116 (2021)

Objective(s): The role of lipoproteins (LDL) as active molecules with preferential tumor interaction, but limited drug delivery capacity, has been previously reported. On the other hand, in a previous report, we demonstrated the high capacity of mono

Externí odkaz: https://doaj.org/article/caaf12954e1d402dbf2853a194de1cf2

Zobrazit plný text záznamu

Expression and localization of tubulin isotypes and its mRNAs during Thecaphora frezii developments

Autor: Ana Cristina Figueroa, María Soledad Díaz, Roxana Valeria Alasino, Pablo Yang, Néstor Walter Soria, Dante Miguel Beltramo

Publikováno v: Figueroa, Ana Cristina ORCID: https://orcid.org/0000-0002-9567-4192 , Díaz, María Soledad ORCID: https://orcid.org/0000-0003-0239-0295 , Alasino, Roxana Valeria ORCID: https://orcid.org/0000-0003-2636-2109 , Yang, Pablo ORCID: https://orcid.org/0000-0001-5206-8873 , Soria, Néstor Walter ORCID: https://orcid.org/0000-0002-8232-1822 and Beltramo, Dante Miguel ORCID: https://orcid.org/0000-0002-8198-3525 (2022) Expression and localization of tubulin isotypes and its mRNAs during Thecaphora frezii developments. FEMS Microbiol Ecology, 98 (11). ISSN 1574-6941

Thecaphora frezii is a phytopathogenic fungus that infects Arachys hypogaea L. and produces peanut smut. It has three ontological stages teliospores, basidiospores, and hyphae. Microtubules are cellular structures that participate in various importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e8eac5df7f4832f9bd80ac1c3d6edb
http://pa.bibdigital.ucc.edu.ar/3681/

Zobrazit plný text záznamu

Nebulization with alkaline hipertonic ibuprofen induces a rapid increase in platelets circulating in COVID-19 patients but not in healthy subjects

Autor: Dante M. Beltramo, Alexis Doresky, Galia Karayan, Oscar Salva, Julieta Borello, Roxana Valeria Alasino, Celia Giller

Publikováno v: Platelets. 33:471-478

We analyze changes in circulating platelets in COVID-19 positive patients who received conventional treatment Dexamethasone and Enoxaparin (Dexa-Enoxa) compared to patients treated with conventional therapy plus nebulization with alkaline hypertonic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc2ef31cb0b547caa8ad5aa6d0f3dc0
https://doi.org/10.1080/09537104.2021.1967918

Zobrazit plný text záznamu

Monosialoganglioside GM1 reduces toxicity of Ptx and increase anti-metastasic effect in a murine mammary cancer model

Autor: Néstor H. García, Victoria Leonhard, Dante M. Beltramo, María Eugenia Pasqualini, David Cremonezzi, Roxana Valeria Alasino

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Having demonstrated the ability of monosialoganglioside GM1 micelles as oncology drug transporter, this work focuses on evaluating its application in an in vivo system, studying the toxicity and antitumoral effect of GM1-Ptx micellar formulation. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b891ea4c2c6008b116b40bcba4eb39
http://link.springer.com/article/10.1038/s41598-020-67256-3

Zobrazit plný text záznamu

Plný text ve formátu HTML

Ibuprofen, a traditional drug that may impact the course of COVID-19 new effective formulation in nebulizable solution

Autor: Sonia E. Muñoz, Dante M. Beltramo, Roxana Valeria Alasino, Néstor H. García, Daniela Josefina Porta

Publikováno v: Medical Hypotheses
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Repositorio Digital Universitario (UNC)
Universidad Nacional de Córdoba
instacron:UNC

The traditional formulation of ibuprofen is poorly soluble in water, so the administered dose must be 10 times higher than the dose required for a therapeutic effect. The development of a hydrosoluble form of ibuprofen can be a strategy to reach a hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e507ab20b5eec6dce2b66bef39f493e

Zobrazit plný text záznamu

Testosterone-loaded GM1 micelles targeted to the intracellular androgen receptor for the specific induction of genomic androgen signaling

Autor: Dante M. Beltramo, Liliana del Valle Sosa, Roxana Valeria Alasino, Victoria Peyret, Cristina Alicia Maldonado, Mariana Micaela Cuello Rubio, Amado Alfredo Quintar, Juan Pablo Nicola, Nahuel Peinetti, María Victoria Scalerandi

Publikováno v: International journal of pharmaceutics. 591

Androgens play a central role in homeostatic and pathological processes of the prostate gland. At the cellular level, testosterone activates both the genomic signaling pathway, through the intracellular androgen receptor (AR), and membrane-initiated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb89ffc868bd4f2a79345071991d9b1
https://pubmed.ncbi.nlm.nih.gov/33069891

Zobrazit plný text záznamu

Biochemical characterization of the interactions between doxorubicin and lipidic GM1 micelles with or without paclitaxel loading

Autor: Dante M. Beltramo, Ismael D. Bianco, Valeria Heredia, Victoria Leonhard, Roxana Valeria Alasino, Ariel Gustavo Garro

Publikováno v: International Journal of Nanomedicine

Victoria Leonhard,1,2 Roxana V Alasino,1,2 Ismael D Bianco,1–3 Ariel G Garro,1 Valeria Heredia,1 Dante M Beltramo1,2,4 1Centro de Excelencia en Productos y Procesos de Córdoba (CEPROCOR), Córdoba, Argentina; 2Consejo Nacional de Investigaciones C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d956fee420353b99f2eaf41a2696c8
http://europepmc.org/articles/PMC4428378

Zobrazit plný text záznamu

Silver Nanoparticles with High Loading Capacity of Amphotericin B: Characterization, Bactericidal and Antifungal Effects

Autor: Roxana Valeria Alasino, Adrian Javier Muñoz, Victoria Leonhard, Dante M. Beltramo

Publikováno v: Current drug delivery. 15(6)

The purpose of this study was to evaluate the most appropriate conditions to generate silver nanoparticles (AgNPs) loaded with a potent antimycotic drug like amphotericin B (AmB), characterize the physicochemical properties, and to evaluate the cytot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ba674d51748c0bc284929bbbb9a95f
https://pubmed.ncbi.nlm.nih.gov/28925873

Zobrazit plný text záznamu

Ethidium Bromide and SYBR Green I Interact with Lipid Micelles

Autor: N. Miotti, Ariel Gustavo Garro, Dante Miguel Beltramo, Roxana Valeria Alasino, Pablo Vélez

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Ethidium Bromide and SYBR Green I are usual examples of ligands that specifically binds to DNA by intercalation. Here we describe that micelles of gangliosides, a lipidic family of sialoglycosphingolipids which are the most important lipids in centra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e273e0b1b3292ea92a1ba03aaf87943
https://doi.org/10.4172/2150-3494.1000152

Zobrazit plný text záznamu

Sialoganglioside Micelles for Enhanced Paclitaxel Solubility: In Vitro Characterization

Autor: Valeria Heredia, Ariel Gustavo Garro, Dante M. Beltramo, Victoria Leonhard, Roxana Valeria Alasino, Bruno Maggio

Publikováno v: Journal of pharmaceutical sciences. 105(1)

Efficiency of mono-sialogangliosides to load Paclitaxel (Ptx) has recently been found to depend on the structure of the polysaccharide chain. In this study, we demonstrated that incorporation of only one more sialic acid into the ganglioside molecule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c93d6765e3baba71cb1900c7fc0fca0
https://pubmed.ncbi.nlm.nih.gov/26852858

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání