Performance of the new EULAR/ACR classification criteria for idiopathic inflammatory myopathies (IIM) in a large monocentric IIM cohort

Autor: Antonella Notarnicola, Karina Roxana Gheorghe, Ingrid E. Lundberg, Louise Ekholm, Anna Tjärnlund, Matteo Bottai, Simone Barsotti, Lara Dani, Valerie Leclaire, Maryam Dastmalchi

Publikováno v: Seminars in Arthritis and Rheumatism. 50:492-497

Background In 2017, the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) published new classification criteria for idiopathic inflammatory myopathies (IIM). Objectives To [1] assess the performance of the EULA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e3afe490b9b5ca7785ef2fc0387fad
https://doi.org/10.1016/j.semarthrit.2019.12.001

A randomised, open-label trial to assess the optimal treatment strategy in early diffuse cutaneous systemic sclerosis: the UPSIDE study protocol

Autor: Roger Hesselstrand, Reinhard E. Voll, Ellen De Langhe, Per Ljungman, Jeska K de Vries-Bouwstra, Madelon C. Vonk, Vanessa Smith, Miro Mayer, Anne C. A. Marijnissen, Jacob M van Laar, Nicoletta Del Papa, Karina Roxana Gheorghe, Paco M. W. Welsing, Anna van Rhenen, Dirk M. Wuttge, Roland Schroers, Tessa Kerre, Erik W.A. Marijt, Julia Spierings, Marc Schmalzing, Arjan A. van de Loosdrecht, Joerg Henes, Ulrich A. Walker, Alexandre E Voskuyl, Daan Dierickx

Publikováno v: BMJ Open, 11
BMJ Open, 11(3). BMJ PUBLISHING GROUP
BMJ Open, 11, 3
BMJ Open, 11(3):e044483. BMJ Publishing Group
BMJ Open, Vol 11, Iss 3 (2021)
BMJ OPEN
Spierings, J, van Rhenen, A, Welsing, P M W, Marijnissen, A C A, de Langhe, E, del Papa, N, Dierickx, D, Gheorghe, K R, Henes, J, Hesselstrand, R, Kerre, T, Ljungman, P, van de Loosdrecht, A A, Marijt, E W A F, Mayer, M, Schmalzing, M, Schroers, R, Smith, V, Voll, R E, Vonk, M C, Voskuyl, A E, de Vries-Bouwstra, J K, Walker, U A, Wuttge, D M & van Laar, J M 2021, ' A randomised, open-label trial to assess the optimal treatment strategy in early diffuse cutaneous systemic sclerosis: The UPSIDE study protocol ', BMJ Open, vol. 11, no. 3, e044483 . https://doi.org/10.1136/bmjopen-2020-044483
BMJ Open

IntroductionSystemic sclerosis (SSc) is a chronic, autoimmune connective tissue disease associated with high morbidity and mortality, especially in diffuse cutaneous SSc (dcSSc). Currently, there are several treatments available in early dcSSc that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe321de3f3691e61f10c0c390a3e5bd
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/232577

Prostaglandin E2 synthesizing enzymes in rheumatoid arthritis B cells and the effects of B cell depleting therapy on enzyme expression.

Autor: Karina Roxana Gheorghe, Rogier M Thurlings, Marie Westman, Maartje J Boumans, Vivianne Malmström, Christina Trollmo, Marina Korotkova, Per-Johan Jakobsson, Paul-Peter Tak

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e16378 (2011)

B cells may play an important role in promoting immune activation in the rheumatoid synovium and can produce prostaglandin E(2) (PGE(2)) when activated. In its turn, PGE(2) formed by cyclooxygenase (COX) and microsomal prostaglandin E(2) synthase 1 (

Externí odkaz: https://doaj.org/article/325174687a224c48b65d84f3155b08b8

Cytosolic 5 '-nucleotidase 1A autoantibody profile and clinical characteristics in inclusion body myositis

Autor: Olivier Benveniste, C Brierley, Anke Rietveld, Stephen R Pye, Christiaan G J Saris, James B. Lilleker, Bryan Lecky, David Hilton-Jones, Pedro Machado, Neil McHugh, Sabrina Sacconi, Robert G. Cooper, Hector Chinoy, Megan K. Herbert, M. Parton, Ingrid E. Lundberg, James Miller, B.G.M. van Engelen, Kuberaka Mariampillai, Umesh A. Badrising, Janine A. Lamb, Michael G. Hanna, Karina Roxana Gheorghe, M T J Peeters, Mark E. Roberts, Ger J. M. Pruijn

Publikováno v: Lilleker, J B, Rietveld, A, Pye, S R, Mariampillai, K, Benveniste, O, Peeters, M T J, Miller, J A L, Hanna, M G, Machado, P M, Parton, M J, Gheorghe, K R, Badrising, U A, Lundberg, I E, Sacconi, S, Herbert, M K, McHugh, N J, Lecky, B R F, Brierley, C, Hilton-Jones, D, Lamb, J A, Roberts, M E, Cooper, R G, Saris, C G J, Pruijn, G J M, Chinoy, H & Engelen, B G M V 2017, ' Cytosolic 5'-nucleotidase 1A autoantibody profile and clinical characteristics in inclusion body myositis ', Annals of the rheumatic diseases, vol. 76, no. 5, pp. 862-868 . https://doi.org/10.1136/annrheumdis-2016-210282, https://doi.org/10.1136/annrheumdis-2016-210282
Annals of the Rheumatic Diseases, 76(5)
Annals of the Rheumatic Diseases
Lilleker, J B, Rietveld, A, Pye, S R, Mariampillai, K, Benveniste, O, Peeters, M T J, Miller, J A L, Hanna, M G, Machado, P M, Parton, M J, Gheorghe, K R, Badrising, U A, Lundberg, I E, Sacconi, S, Herbert, M K, McHugh, N J, Lecky, B R F, Brierley, C, Hilton-Jones, D, Lamb, J A, Roberts, M E, Cooper, R G, Saris, C G J, Pruijn, G J M, Chinoy, H, van Engelen, B G M 2017, ' Cytosolic 5'-nucleotidase 1A autoantibody profile and clinical characteristics in inclusion body myositis ', Annals of the Rheumatic Diseases, vol. 76, no. 5 . https://doi.org/10.1136/annrheumdis-2016-210282

ObjectivesAutoantibodies directed against cytosolic 5′-nucleotidase 1A have been identified in many patients with inclusion body myositis. This retrospective study investigated the association between anticytosolic 5′-nucleotidase 1A antibody sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dced853f227bacad031f9a610fe9bae
https://doi.org/10.1136/annrheumdis-2016-210282

Autoantibodies to cytosolic 5′-nucleotidase 1A in inclusion body myositis

Autor: Bas J. A. van Hoeve, Ingrid E. Lundberg, Annemarie van der Heijden, Wilbert C. Boelens, Helenius J. Schelhaas, Sander H. J. van Dooren, Marcel M. Verbeek, Judith Stammen-Vogelzangs, Umesh A. Badrising, Baziel G.M. van Engelen, Snjolaug Arnardottir, Helma Pluk, Karina Roxana Gheorghe, Ger J. M. Pruijn

Publikováno v: Annals of Neurology. 73:397-407

OBJECTIVE: Sporadic inclusion body myositis (sIBM) is an inflammatory myopathy characterized by both degenerative and autoimmune features. In contrast to other inflammatory myopathies, myositis-specific autoantibodies had not been found in sIBM patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0737bd8adf765cff4261dddc0b6f7350
https://doi.org/10.1002/ana.23822