Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Roxana E. Oberkersch"'
Publikováno v:
Cardiovascular Research.
Aims The circadian clock is an internal biological timer that co-ordinates physiology and gene expression with the 24-h solar day. Circadian clock perturbations have been associated to vascular dysfunctions in mammals, and a function of the circadian
Autor:
Nicola Facchinello, Matteo Astone, Matteo Audano, Roxana E. Oberkersch, Marianna Spizzotin, Enrica Calura, Madalena Marques, Mihaela Crisan, Nico Mitro, Massimo M. Santoro
Publikováno v:
Nature Metabolism
Facchinello, N, Astone, M, Audano, M, Oberkersch, R E, Spizzotin, M, Calura, E, Marques, M, Crisan, M, Mitro, N & Santoro, M M 2022, ' Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition ', Nature Metabolism, vol. 4, no. 1, pp. 123-140 . https://doi.org/10.1038/s42255-021-00514-4
Facchinello, N, Astone, M, Audano, M, Oberkersch, R E, Spizzotin, M, Calura, E, Marques, M, Crisan, M, Mitro, N & Santoro, M M 2022, ' Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition ', Nature Metabolism, vol. 4, no. 1, pp. 123-140 . https://doi.org/10.1038/s42255-021-00514-4
Vascular mural cells (vMCs) play an essential role in the development and maturation of the vasculature by promoting vessel stabilization through their interactions with endothelial cells. Whether endothelial metabolism influences mural cell recruitm
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::875a6490c004b5cb05b13de83e21c277
https://doi.org/10.1007/978-1-0716-2703-7_15
https://doi.org/10.1007/978-1-0716-2703-7_15
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2572
The use of transgenic animals carrying exogenous DNA integrated in their genome is a routine in modern-day laboratories. Nowadays, the zebrafish system represents the most useful tool for transgenesis studies mainly due to easy accessibility and mani
Publikováno v:
Nature metabolism. 4(6)
Autor:
Roxana E. Oberkersch, Giovanna Pontarin, Matteo Astone, Marianna Spizzotin, Liaisan Arslanbaeva, Giovanni Tosi, Emiliano Panieri, Sara Ricciardi, Maria Francesca Allega, Alessia Brossa, Paolo Grumati, Benedetta Bussolati, Stefano Biffo, Saverio Tardito, Massimo M. Santoro
Angiogenesis, the active formation of new blood vessels from pre-existing ones, is a complex and demanding biological process that plays an important role in physiological as well as pathological settings. Recent evidence supports cell metabolism as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef01762b0a666724967e4c91e48d5931
https://hdl.handle.net/11588/899906
https://hdl.handle.net/11588/899906
Cancer is a leading cause of death worldwide. If left untreated, tumors tend to grow and spread uncontrolled until the patient dies. To support this growth, cancer cells need large amounts of nutrients and growth factors that are supplied and distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f9456e4bb6d8e26b010b24740e7724
http://hdl.handle.net/11577/3455788
http://hdl.handle.net/11577/3455788
Publikováno v:
Nature Metabolism. 4:645-646
Autor:
Dora Tortarolo, Guido Serini, Chiara Sandri, Donatella Valdembri, Giulia Villari, Matteo Astone, Marco Arese, Chiara Camillo, Roxana E. Oberkersch, Dafne Gays, Noemi Gioelli, Fabiana Clapero, Giulia Mana, Massimo M. Santoro, Nicola Facchinello, Luca Tamagnone
Publikováno v:
bioRxiv
Dynamic modulation of endothelial cell-to-cell and cell-to-extracellular matrix (ECM) adhesion is essential for blood vessel patterning and functioning. Yet, the molecular mechanisms involved in this process have not been completely deciphered. We id
Publikováno v:
Vascular Pharmacology
The role of endothelial metabolism represents a crucial element governing the formation and the differentiation of blood vessels, termed angiogenesis. Besides glycolysis and fatty acid oxidation, endothelial cells rely on specific amino acids to prol