Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Roxana A. Radu"'
Autor:
Cheng Fu, Nan Yang, Jen-Zen Chuang, Nobuyuki Nakajima, Satoshi Iraha, Neeta Roy, Zhenquan Wu, Zhichun Jiang, Wataru Otsu, Roxana A. Radu, Howard Hua Yang, Maxwell Ping Lee, Tilla S. Worgall, Wen-Cheng Xiong, Ching-Hwa Sung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Vacuolar protein sorting 35 (VPS35), the core component of the retromer complex which regulates endosomal trafficking, is genetically linked with Parkinson’s disease (PD). Impaired vision is a common non-motor manifestation of PD. Here, we
Externí odkaz:
https://doaj.org/article/6795212de22b42e1b120beca529a58fb
Autor:
Sameeha Jilani, Justin D. Saco, Edurne Mugarza, Aleida Pujol-Morcillo, Jeffrey Chokry, Clement Ng, Gabriel Abril-Rodriguez, David Berger-Manerio, Ami Pant, Jane Hu, Rubi Gupta, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Jia M. Chen, Daniel Sanghoon Shin, Philip Scumpia, Roxana A. Radu, Yvonne Chen, Antoni Ribas, Cristina Puig-Saus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract A major limitation to developing chimeric antigen receptor (CAR)-T cell therapies for solid tumors is identifying surface proteins highly expressed in tumors but not in normal tissues. Here, we identify Tyrosinase Related Protein 1 (TYRP1) a
Externí odkaz:
https://doaj.org/article/cd2701d25f8e48e2a9b53f8ebd1a39b3
Autor:
Eunice Sze Yin Ng, Nermin Kady, Jane Hu, Arpita Dave, Zhichun Jiang, Jacqueline Pei, Michael B. Gorin, Anna Matynia, Roxana A. Radu
Publikováno v:
Cells, Vol 11, Iss 21, p 3462 (2022)
Recessive Stargardt disease (STGD1) is an inherited retinopathy caused by mutations in the ABCA4 gene. The ABCA4 protein is a phospholipid-retinoid flippase in the outer segments of photoreceptors and the internal membranes of retinal pigment epithel
Externí odkaz:
https://doaj.org/article/182604b4edaa4086ad8c400026a6bd81
Autor:
Jane Hu, Gayle J. Pauer, Stephanie A. Hagstrom, Dean Bok, Meghan J. DeBenedictis, Vera L. Bonilha, Joe G. Hollyfield, Roxana A. Radu
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101787- (2020)
Stargardt macular degeneration (STGD) is a central blinding disease caused by loss of or dysfunctional ABCA4 transporter in both photoreceptors and retinal pigment epithelial (RPE) cells. Toxic bisretinoid-lipofuscin buildup in the RPE cells is a pat
Externí odkaz:
https://doaj.org/article/b7d94d1bd38d413b8716902557463c7b
Autor:
Elliot W. Kim, Avelino De Leon, Zhichun Jiang, Roxana A. Radu, Adrian R. Martineau, Edward D. Chan, Xiyuan Bai, Wen-Lin Su, Dennis J. Montoya, Robert L. Modlin, Philip T. Liu
Publikováno v:
mSphere, Vol 4, Iss 3 (2019)
ABSTRACT Epidemiological evidence correlates low serum vitamin A (retinol) levels with increased susceptibility to active tuberculosis (TB); however, retinol is biologically inactive and must be converted into its bioactive form, all-trans retinoic a
Externí odkaz:
https://doaj.org/article/d742d0149e544e31881c00788a5150dc
Autor:
Călin Jianu, Alexandra Teodora Lukinich-Gruia, Matilda Rădulescu, Marius Mioc, Alexandra Mioc, Codruța Șoica, Albert Titus Constantin, Ioan David, Gabriel Bujancă, Roxana Ghircău Radu
Publikováno v:
Applied Sciences; Volume 13; Issue 8; Pages: 5076
This investigation aims to assess the chemical composition and antioxidant properties of Origanum vulgare var. aureum L. essential oil (OEO). The oil was obtained with a 0.34% (v/w dried weight) yield and investigated by gas chromatography-mass spect
Autor:
Ala Morshedian, Gabriela Sendek, Sze Yin Ng, Kimberly Boyd, Roxana A. Radu, Mingyao Liu, Nikolai O. Artemyev, Alapakkam P. Sampath, Gordon L. Fain
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 11
J Neurosci
J Neurosci
The high sensitivity of night vision requires that rod photoreceptors reliably and reproducibly signal the absorption of single photons, a process that depends on tight regulation of intracellular cGMP concentration through the phototransduction casc
Autor:
Roxana Cristina RADU
Publikováno v:
Anuarul Institutului de Cercetări Socio-Umane „C.S. Nicolăescu-Plopşor”, Iss XXII, Pp 129-140 (2021)
Pregnant, childbirth or breastfeeding employees are protected against dismissal under national and European Union law. Thus, EU legislation concerning maternity protection at work establishes the prohibition of dismissal of employees who are on mater
Autor:
Raluca Maracineanu, Marilena Motoc, Roxana M. Talpos-Niculescu, Roxana Ghircau-Radu, Serban Talpos-Niculescu, Marius O. Pricop
Publikováno v:
Cranio : the journal of craniomandibular practice.
Pterygoid hamulus syndrome, a painful oral and facial syndrome, has been described in literature to be correlated with morphological changes in the length of the pterygoid hamulus of the sphenoid bone.The current case report describes the treatment f
Autor:
Codrin-Constantin Burlacu, Andrei-Vlad Badulescu, Adrian Pavel Trifa, Cristiana Varacas, Roxana-Maria Radu, Vitalie Varacas
Publikováno v:
Česká a slovenská neurologie a neurochirurgie.