Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Roxana, Pincheira"'
Autor:
Mario Palma, Elizabeth Riffo, Alejandro Farias, Viviana Coliboro-Dannich, Luis Espinoza-Francine, Emilia Escalona, Roberto Amigo, José L. Gutiérrez, Roxana Pincheira, Ariel F. Castro
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract Background mTORC2 is a critical regulator of cytoskeleton organization, cell proliferation, and cancer cell survival. Activated mTORC2 induces maximal activation of Akt by phosphorylation of Ser-473, but regulation of Akt activity and signal
Externí odkaz:
https://doaj.org/article/b147c3f3e6e94b8ca50919e790866969
Autor:
Elizabeth Riffo, Mario Palma, Matías I. Hepp, Diego Benítez-Riquelme, Vicente A. Torres, Ariel F. Castro, Roxana Pincheira
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
SALL2/Sall2 is a transcription factor associated with development, neuronal differentiation, and cancer. Interestingly, SALL2/Sall2 deficiency leads to failure of the optic fissure closure and neurite outgrowth, suggesting a positive role for SALL2/S
Externí odkaz:
https://doaj.org/article/64401843b61e4f34b0ec658c4fed69dd
Publikováno v:
Revista Venezolana de Gerencia, Vol 27, Iss 100 (2022)
En enero de 2019 entró en vigencia la Norma Internacional de Información Financiera (NIIF) Nº16 sobre arrendamientos. El objetivo de este trabajo es analizar los efectos de su aplicación y para ello se estudiaron 30 empresas adscritas al Índice
Externí odkaz:
https://doaj.org/article/8253c71f37f94facad2275ddaaf1da74
Autor:
Marisol Estrella Armijo, Emilia Escalona, Daniela Peña, Alejandro Farias, Violeta Morin, Matthias Baumann, Bert Matthias Klebl, Roxana Pincheira, Ariel Fernando Castro
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rheb is a small GTPase member of the Ras superfamily and an activator of mTORC1, a protein complex master regulator of cell metabolism, growth, and proliferation. Rheb/mTORC1 pathway is hyperactivated in proliferative diseases, such as Tuberous Scler
Externí odkaz:
https://doaj.org/article/b836196e338f4d45b9d4ac930431cb8c
Publikováno v:
Estudios Gerenciales, Vol 36, Iss 154, Pp 56-65 (2020)
Esta investigación analiza si la presentación de los reportes de sustentabilidad, su auditoría y el uso de estándares internacionales de auditoría (ISAE3000-AA1000) tienen un efecto en la liquidez del mercado chileno. Se realiza un análisis com
Externí odkaz:
https://doaj.org/article/31169ad0d937461688a2e37d051c5d8a
Autor:
Carlos Farkas, Aracelly Quiroz, Claudia Alvarez, Viviana Hermosilla, Carlos F. Aylwin, Alejandro Lomniczi, Ariel F. Castro, Matias I. Hepp, Roxana Pincheira
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The SALL2 transcription factor, an evolutionarily conserved gene through vertebrates, is involved in normal development and neuronal differentiation. In disease, SALL2 is associated with eye, kidney, and brain disorders, but mainly is related to canc
Externí odkaz:
https://doaj.org/article/6932d3d8158c4b3a8e4533cb678e9058
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
NUAK1 is an AMPK-related kinase located in the cytosol and the nucleus, whose expression associates with tumor malignancy and poor patient prognosis in several cancers. Accordingly, NUAK1 was associated with metastasis because it promotes cell migrat
Externí odkaz:
https://doaj.org/article/34dc9df67cb64b02a140eb2b5e09b602
Autor:
Viviana E. Hermosilla, Ginessa Salgado, Elizabeth Riffo, David Escobar, Matías I. Hepp, Carlos Farkas, Mario Galindo, Violeta Morín, María A. García‐Robles, Ariel F. Castro, Roxana Pincheira
Publikováno v:
Molecular Oncology, Vol 12, Iss 7, Pp 1026-1046 (2018)
SALL2 is a poorly characterized transcription factor that belongs to the Spalt‐like family involved in development. Mutations on SALL2 have been associated with ocular coloboma and cancer. In cancers, SALL2 is deregulated and is proposed as a tumor
Externí odkaz:
https://doaj.org/article/856cbb2f85544e4fa11c6cd60077a716
Autor:
Claudia Álvarez, Aracelly Quiroz, Diego Benítez-Riquelme, Elizabeth Riffo, Ariel F. Castro, Roxana Pincheira
Publikováno v:
Cancers, Vol 13, Iss 24, p 6292 (2021)
SALL proteins are a family of four conserved C2H2 zinc finger transcription factors that play critical roles in organogenesis during embryonic development. They regulate cell proliferation, survival, migration, and stemness; consequently, they are in
Externí odkaz:
https://doaj.org/article/a8427a9818314a01a58675410988447c
Autor:
Daniela Matei, Harikrishna Nakshatri, Robert Bigsby, Robert Emerson, Roxana Pincheira, Liyun Cao, Minati Satpathy
Tissue transglutaminase (TG2) is involved in Ca2+-dependent aggregation and polymerization of proteins. We previously reported that TG2 mRNA is up-regulated in epithelial ovarian cancer (EOC) cells compared with normal ovarian epithelium. Here, we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a10babd772060a14fd3606e62bfd6d3
https://doi.org/10.1158/0008-5472.c.6495477.v1
https://doi.org/10.1158/0008-5472.c.6495477.v1