Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Rowley TF"'
1
Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format
Autor: Hussain, K, Hargreaves, CE, Rowley, TF, Sopp, JM, Latham, KV, Bhatta, P, Sherington, J, Cutler, RM, Humphreys, DP, Glennie, MJ, Strefford, JC, Cragg, MS
Publikováno v: Frontiers in Immunology
Monoclonal antibody (mAb) immunotherapy has transformed the treatment of allergy, autoimmunity, and cancer. The interaction of mAb with Fc gamma receptors (FcγR) is often critical for efficacy. The genes encoding the low-affinity FcγR have single n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1b7e94b222d525446333af6493afa377
http://europepmc.org/articles/PMC6417454
Zobrazit plný text záznamu
2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
5
Akademický článek
Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer.
Autor: Davies GCG; UCB Pharma, Slough, UK., Dedi N; UCB Pharma, Slough, UK., Jones PS; UCB Pharma, Slough, UK., Kevorkian L; UCB Pharma, Slough, UK., McMillan D; UCB Pharma, Slough, UK., Ottone C; UCB Pharma, Slough, UK., Schulze MED; UCB Pharma, Slough, UK., Scott-Tucker A; UCB Pharma, Slough, UK., Tewari R; UCB Pharma, Slough, UK., West S; UCB Pharma, Slough, UK., Wright M; UCB Pharma, Slough, UK., Rowley TF; UCB Pharma, Slough, UK.
Publikováno v: MAbs [MAbs] 2023 Jan-Dec; Vol. 15 (1), pp. 2289681. Date of Electronic Publication: 2023 Dec 12.
Zobrazit plný text záznamu
6
Akademický článek
On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.
Autor: Sopp JM; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Peters SJ; UCB Pharma, Slough, UK., Rowley TF; UCB Pharma, Slough, UK., Oldham RJ; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., James S; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Mockridge I; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., French RR; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Turner A; UCB Pharma, Slough, UK., Beers SA; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Humphreys DP; UCB Pharma, Slough, UK., Cragg MS; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. msc@soton.ac.uk.
Publikováno v: Communications biology [Commun Biol] 2021 Sep 02; Vol. 4 (1), pp. 1031. Date of Electronic Publication: 2021 Sep 02.
Zobrazit plný text záznamu
7
Akademický článek
Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions.
Autor: Rowley TF; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK. tania.rowley@ucb.com., Peters SJ; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Aylott M; Statistical Consultant, St Albans, UK., Griffin R; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Davies NL; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Healy LJ; Aurelia Bioscience, Nottingham, UK., Cutler RM; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Eddleston A; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Pither TL; Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, UK., Sopp JM; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Zaccheo O; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Fossati G; Eurofins Pharma Bioanalysis Services UK Ltd, Abingdon, UK., Cain K; Vertex, Abingdon, UK., Ventom AM; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Hailu H; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Ward EJ; Biochemical Pharmacology William Harvey Research Institute, Queen Mary University of London, London, UK., Sherington J; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Brennan FR; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Fallah-Arani F; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Humphreys DP; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK.
Publikováno v: Communications biology [Commun Biol] 2018 Sep 14; Vol. 1, pp. 146. Date of Electronic Publication: 2018 Sep 14 (Print Publication: 2018).
Zobrazit plný text záznamu
8
Akademický článek
Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions.
Autor: Qureshi OS; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Rowley TF; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Junker F; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Peters SJ; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Crilly S; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Compson J; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Eddleston A; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Björkelund H; Ridgeview Diagnostics AB, Uppsala Science Park, SE75183, Uppsala, Sweden., Greenslade K; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Parkinson M; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Davies NL; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Griffin R; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Pither TL; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Cain K; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Christodoulou L; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Staelens L; UCB Biopharma Sprl., Chemin du Foriest, Braine l'Alleud, Belgium., Ward E; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Tibbitts J; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Kiessling A; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Smith B; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Brennan FR; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Malmqvist M; Ridgeview Diagnostics AB, Uppsala Science Park, SE75183, Uppsala, Sweden., Fallah-Arani F; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK., Humphreys DP; UCB Pharma, 216 Bath Road, Slough, SL1 3WE, UK. david.humphreys@ucb.com.
Publikováno v: Scientific reports [Sci Rep] 2017 Dec 06; Vol. 7 (1), pp. 17049. Date of Electronic Publication: 2017 Dec 06.
Zobrazit plný text záznamu
9
Akademický článek
CD27 costimulation contributes substantially to the expansion of functional memory CD8(+) T cells after peptide immunization.
Autor: Taraban VY; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK., Rowley TF, Kerr JP, Willoughby JE, Johnson PM, Al-Shamkhani A, Buchan SL
Publikováno v: European journal of immunology [Eur J Immunol] 2013 Dec; Vol. 43 (12), pp. 3314-23. Date of Electronic Publication: 2013 Oct 01.
Zobrazit plný text záznamu
10
Akademický článek
Triggering of TNFRSF25 promotes CD8⁺ T-cell responses and anti-tumor immunity.
Autor: Slebioda TJ; Cancer Sciences Division, University of Southampton School of Medicine, Southampton General Hospital, Southampton, United Kingdom., Rowley TF, Ferdinand JR, Willoughby JE, Buchan SL, Taraban VY, Al-Shamkhani A
Publikováno v: European journal of immunology [Eur J Immunol] 2011 Sep; Vol. 41 (9), pp. 2606-11. Date of Electronic Publication: 2011 Aug 04.
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje