Chromatin protein complexes involved in gene repression in lamina-associated domains.

Autor: Manzo SG; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands.; Department of Biosciences, Università degli Studi di Milano, Via Celoria 26, 20133, Milan, Italy., Mazouzi A; Oncode Institute, Amsterdam, the Netherlands.; Division of Biochemistry, Netherlands Cancer Institute, Amsterdam, the Netherlands., Leemans C; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., van Schaik T; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., Neyazi N; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., van Ruiten MS; Division of Cell Biology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Rowland BD; Division of Cell Biology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Brummelkamp TR; Oncode Institute, Amsterdam, the Netherlands.; Division of Biochemistry, Netherlands Cancer Institute, Amsterdam, the Netherlands., van Steensel B; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands. b.v.steensel@nki.nl.; Oncode Institute, Amsterdam, the Netherlands. b.v.steensel@nki.nl.; Division of Molecular Genetics, Netherlands Cancer Institute, Amsterdam, the Netherlands. b.v.steensel@nki.nl.

Publikováno v: The EMBO journal [EMBO J] 2024 Nov; Vol. 43 (21), pp. 5260-5287. Date of Electronic Publication: 2024 Sep 25.

Cell biology: Converging paths to cohesion.

Autor: Oldenkamp R; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Rowland BD; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address: b.rowland@nki.nl.

Publikováno v: Current biology : CB [Curr Biol] 2024 Jul 22; Vol. 34 (14), pp. R680-R682.

Genetic determinants of micronucleus formation in vivo.

Autor: Adams DJ; Wellcome Sanger Institute, Cambridge, UK. da1@sanger.ac.uk., Barlas B; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., McIntyre RE; Wellcome Sanger Institute, Cambridge, UK., Salguero I; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., van der Weyden L; Wellcome Sanger Institute, Cambridge, UK., Barros A; Wellcome Sanger Institute, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Vicente JR; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Karimpour N; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Haider A; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Ranzani M; Wellcome Sanger Institute, Cambridge, UK., Turner G; Wellcome Sanger Institute, Cambridge, UK., Thompson NA; Wellcome Sanger Institute, Cambridge, UK., Harle V; Wellcome Sanger Institute, Cambridge, UK., Olvera-León R; Wellcome Sanger Institute, Cambridge, UK., Robles-Espinoza CD; Wellcome Sanger Institute, Cambridge, UK.; Laboratorio Internacional de Investigación Sobre el Genoma Humano, Universidad Nacional Autónoma de México, Santiago de Querétaro, México., Speak AO; Wellcome Sanger Institute, Cambridge, UK., Geisler N; Wellcome Sanger Institute, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Weninger WJ; Division of Anatomy, MIC, Medical University of Vienna, Wien, Austria., Geyer SH; Division of Anatomy, MIC, Medical University of Vienna, Wien, Austria., Hewinson J; Wellcome Sanger Institute, Cambridge, UK., Karp NA; Wellcome Sanger Institute, Cambridge, UK., Fu B; Wellcome Sanger Institute, Cambridge, UK., Yang F; Wellcome Sanger Institute, Cambridge, UK., Kozik Z; Functional Proteomics Group, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK., Choudhary J; Functional Proteomics Group, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK., Yu L; Functional Proteomics Group, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK., van Ruiten MS; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Rowland BD; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Lelliott CJ; Wellcome Sanger Institute, Cambridge, UK., Del Castillo Velasco-Herrera M; Wellcome Sanger Institute, Cambridge, UK., Verstraten R; Wellcome Sanger Institute, Cambridge, UK., Bruckner L; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.; Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany., Henssen AG; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.; Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany.; Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), partner site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Rooimans MA; Department of Human Genetics, Section of Oncogenetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands., de Lange J; Department of Human Genetics, Section of Oncogenetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands., Mohun TJ; Division of Developmental Biology, MRC, National Institute for Medical Research, London, UK., Arends MJ; Division of Pathology, Cancer Research UK Scotland Centre, Institute of Genetics & Cancer The University of Edinburgh, Edinburgh, UK., Kentistou KA; MRC Epidemiology Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Coelho PA; Department of Genetics, University of Cambridge, Cambridge, UK., Zhao Y; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Zecchini H; Metabolic Research Laboratory, Wellcome-MRC Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Perry JRB; MRC Epidemiology Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Metabolic Research Laboratory, Wellcome-MRC Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Jackson SP; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Institute, Cambridge, UK., Balmus G; Wellcome Sanger Institute, Cambridge, UK. gb318@cam.ac.uk.; UK Dementia Research Institute at the University of Cambridge, University of Cambridge, Cambridge, UK. gb318@cam.ac.uk.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. gb318@cam.ac.uk.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK. gb318@cam.ac.uk.; Department of Molecular Neuroscience, Transylvanian Institute of Neuroscience, Cluj-Napoca, Romania. gb318@cam.ac.uk.

Publikováno v: Nature [Nature] 2024 Mar; Vol. 627 (8002), pp. 130-136. Date of Electronic Publication: 2024 Feb 14.

Genome control by SMC complexes.

Autor: Hoencamp C; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Rowland BD; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. b.rowland@nki.nl.

Publikováno v: Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2023 Sep; Vol. 24 (9), pp. 633-650. Date of Electronic Publication: 2023 May 25.

The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism.

Autor: van Ruiten MS; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., van Gent D; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Sedeño Cacciatore Á; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Fauster A; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Willems L; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Hekkelman ML; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Hoekman L; Proteomics Facility, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Altelaar M; Proteomics Facility, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute for Pharmaceutical Sciences, Utrecht University and Netherlands Proteomics Centre, Utrecht, the Netherlands., Haarhuis JHI; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Brummelkamp TR; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., de Wit E; Division of Gene Regulation, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Rowland BD; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. b.rowland@nki.nl.

Publikováno v: Nature structural & molecular biology [Nat Struct Mol Biol] 2022 Jun; Vol. 29 (6), pp. 586-591. Date of Electronic Publication: 2022 Jun 16.