Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rowena Kemp"'
Autor:
Madhav Swaminathan, Qing Ma, Amit X. Garg, Mary Lee Myers, Lin Ruo Guo, Prasad Devarajan, Michael W.A. Chu, Cary S. Passik, Chirag R. Parikh, Charles L. Edelstein, Arnar Geirsson, Isabel Butrymowicz, Martin Goldbach, Jay L. Koyner, Ana Palijan, Michael L. Dewar, John A. Elefteriades, Judy Nagy, Rachel E. Griffiths, Richard J. Novick, Susan Garwood, Mac Quantz, Jai Raman, Sabet W. Hashim, Valluvan Jeevanandam, Neil McKenzie, Michael G. Shlipak, Heather Thiessen-Philbrook, Michael Zappitelli, Steven G. Coca, Michael J. Bennett, Umer Darr, Laura Webster, Shahab A. Akhter, Uptal D. Patel, Rowena Kemp, Virginia Schumann
Publikováno v:
American Journal of Kidney Diseases. 66:1006-1014
Background The interaction between baseline kidney function and the performance of biomarkers of acute kidney injury (AKI) on the development of AKI is unclear. Study Design Post hoc analysis of prospective cohort study. Setting & Participants The 1,
Autor:
Praveen N. Chander, Michael S. Goligorsky, Rena Hu, Tatyana N. Orlova, Renato V. Iozzo, Natalia Mendelev, Gang Hao, Daniel Patschan, Steven S. Gross, Veronica Delaney, Edmond O'Riordan, Rowena Kemp
Publikováno v:
PROTEOMICS - CLINICAL APPLICATIONS. 2:1025-1035
The pathogenesis of progressive renal allograft injury, which is termed chronic allograft nephropathy (CAN), remains obscure and is currently defined by histology. Prospective protocolbiopsy trials have demonstrated that clinical and standard laborat
Autor:
Dao-Hong Lin, Yan Jin, Tong Wang, Rowena Kemp, Wen-Hui Wang, Zhijian Wang, Elisa Babilonia, Peng Sun, Alberto Nasjletti
Publikováno v:
American Journal of Physiology-Renal Physiology. 291:F1192-F1200
We previously demonstrated that arachidonic acid (AA) inhibits epithelial Na channels (ENaC) through the cytochrome P-450 (CYP) epoxygenase-dependent pathway ( 34 ). In the present study, we tested the hypothesis that low Na intake suppresses the exp
Autor:
Nader G. Abraham, Thomas H. Hintze, Huan Deng, Tsuneo Ishizuka, Frank Zhang, Alberto Nasjletti, Michael S. Wolin, Michal Laniado-Schwartzman, Harpreet Singh, Jishi Wang, Rowena Kemp
Publikováno v:
Circulation Research. 98:962-969
Vascular cytochrome P450 (CYP) 4A enzymes catalyze the synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE), an eicosanoid which participates in the regulation of vascular tone by sensitizing the smooth muscle cells to constrictor and myogenic stim
Autor:
John R. Falck, Harpreet Singh, Venkat Raj Gopal, Alberto Nasjletti, Huan Deng, Rowena Kemp, Fan Zhang, Michal Laniado-Schwartzman
Publikováno v:
Hypertension. 45:103-108
We compared renal interlobar arteries of spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) in terms of cytochrome P450 (CYP) 4A and CYP2E1 protein expression; levels of 20-HETE, 19-HETE, and 18-HETE; and responsiveness to phenylephrin
Autor:
Joseph M. Miano, Rowena Kemp, Nader G. Abraham, Miao Jiang, Alexandre Mezentsev, John R. Falck, Michal Laniado-Schwartzman, Alberto Nasjletti, Kihwan Byun
Publikováno v:
Circulation Research. 94:167-174
Cytochrome P450 (CYP) 4A1 has been characterized as the most efficient arachidonic acid ω-hydroxylase catalyzing the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), a potent constrictor of the renal and cerebral microcirculation and a mitoge
Autor:
Ganesh S.S. Yaddanapudi, John R. Falck, Alberto Nasjletti, Wen-Hui Wang, Dao-Hong Lin, Rowena Kemp, Yuan Wei
Publikováno v:
The Journal of General Physiology
We used the patch-clamp technique to study the effect of arachidonic acid (AA) on epithelial Na channels (ENaC) in the rat cortical collecting duct (CCD). Application of 10 μM AA decreased the ENaC activity defined by NPo from 1.0 to 0.1. The dose
Autor:
Jun Ichi Kaide, Liming Yang, Alberto Nasjletti, Michael Balazy, Rowena Kemp, Nader G. Abraham, Weiying Gong, Fan Zhang, Houli Jiang, Shuo Quan
Publikováno v:
Scopus-Elsevier
Pulmonary intralobar arteries express heme oxygenase (HO)-1 and -2 and release carbon monoxide (CO) during incubation in Krebs buffer. Acute hypoxia elicits isometric tension development (0.77 ± 0.06 mN/mm) in pulmonary vascular rings treated with 1
Publikováno v:
Hypertension. 42:680-684
We examined the effects of heme administration (15 mg/kg IV) on indexes of renal carbon monoxide production and contrasted the renal functional response to heme in anesthetized rats pretreated and not pretreated with stannous mesoporphyrin (40 μmol/
Autor:
Huan Deng, Alberto Nasjletti, Harpreet Singh, Michal L. Schwartzman, Rowena Kemp, Tsuneo Ishizuka, Jennifer Cheng
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 50(1)
Epidemiological evidence suggests a role for sex-dependent mechanisms in the pathophysiology of hypertension. It has been shown that 5α-dihydrotestosterone (DHT) administration (56 mg/kg of body weight per day IP for 14 days) increases blood pressur