Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rowena D. Devlin"'
Autor:
Graeme K. Worth, Richard L. Prince, Neil Kent, Rowena D. Devlin, R.W. Retallack, Donald H. Gutteridge, V. Grill, Anna J. Fenton
Publikováno v:
Journal of Bone and Mineral Research. 9:81-85
We report the prolonged biochemical changes that occurred in patients with Paget's disease when treated for 2-10 days with pamidronate disodium (3-amino-1-hydroxypropylidine-1,1-bisphosphonate, APD), by i.v. administration and observed for 6 months f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff05d06e2339b285831bee60c1f2232
https://doi.org/10.1002/jbmr.5650090112
https://doi.org/10.1002/jbmr.5650090112
Autor:
Melissa Alsina, Sun Jin Choi, Rowena D. Devlin, Jose C. Cruz, Hoyeon Chung, G. David Roodman, Fiona E. Craig
Publikováno v:
Blood. 96:671-675
This study was designed to determine if macrophage inhibitory protein-1 alpha (MIP-1 alpha), a recently described osteoclast (OCL) stimulatory factor,(1) was present in marrow from patients with multiple myeloma (MM) and possibly involved in the bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4982928d0e810ecbda4980e816eb9e57
https://doi.org/10.1182/blood.v96.2.671.014k24_671_675
https://doi.org/10.1182/blood.v96.2.671.014k24_671_675
Autor:
Sun Jin Choi, Yair Gazitt, G. David Roodman, Sakamuri V. Reddy, Rowena D. Devlin, Cheikh Menaa
Publikováno v:
Journal of Clinical Investigation. 103:1605-1613
Annexin II (AXII), a calcium-dependent phospholipid-binding protein, has been recently found to be an osteoclast (OCL) stimulatory factor that is also secreted by OCLs. In vitro studies showed that AXII induced OCL formation and bone resorption. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7330766ab921e89dbb458e9332bb6694
https://doi.org/10.1172/jci6374
https://doi.org/10.1172/jci6374
Autor:
G. David Roodman, Toshi Yoneda, Riko Nishimura, Cheikh Menaa, Sakamuri V. Reddy, Mark Dallas, Rowena D. Devlin, Sun Jin Choi
Publikováno v:
Journal of Cellular Physiology. 177:636-645
Using an expression cloning approach, we identified and cloned a novel intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption, termed OSF. Conditioned media from 293 cells transiently transfecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be135f1894b1681bd610ff849aac9794
https://doi.org/10.1002/(sici)1097-4652(199812)177:4<636::aid-jcp14>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199812)177:4<636::aid-jcp14>3.0.co
Publikováno v:
Journal of Bone and Mineral Research. 13:393-399
A potent interleukin-6 (IL-6) antagonist (Sant 5), which binds tightly to the IL-6alpha receptor but has impaired gp130 heterodimerization, has been developed recently by site-directed mutagenesis of human IL-6. We report here that Sant 5 inhibits IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049101be5c69e2644598993f9d65e03f
https://doi.org/10.1359/jbmr.1998.13.3.393
https://doi.org/10.1359/jbmr.1998.13.3.393
Autor:
Melissa Alsina, Rowena D. Devlin, Brendan F. Boyce, G. D. Roodman, Judith L. Anderson, Fiona E. Craig, Gregory R. Mundy
Publikováno v:
Blood. 87:1495-1501
Osteolytic bone destruction and its complications, bone pain, pathologic fractures, and hypercalcemia, are a major source of morbidity and mortality in patients with multiple myeloma. The bone destruction in multiple myeloma is due to increased osteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe67607dc4ec0ca0e3015f80e31f244a
https://doi.org/10.1182/blood.v87.4.1495.bloodjournal8741495
https://doi.org/10.1182/blood.v87.4.1495.bloodjournal8741495
Autor:
Sun Jin Choi, Rowena D. Devlin, Hoyeon Chung, Brendan F. Boyce, G. David Roodman, Cheikh Menaa, Sakamuri V. Reddy
Publikováno v:
The Journal of biological chemistry. 274(39)
We screened a human osteoclast (OCL) cDNA expression library for OCL inhibitory factors and identified a clone that blocked both human and murine OCL formation and bone resorption by more than 60%. This clone was identical to human legumain, a cystei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba76b46b72261c285ae6a8e02882eeb
https://pubmed.ncbi.nlm.nih.gov/10488118
https://pubmed.ncbi.nlm.nih.gov/10488118
Increased osteoclast activity is responsible for the enhanced bone destruction in postmenopausal osteoporosis, Paget's disease, bone metastasis, and hypercalcemia of malignancy. However, the number of known inhibitory factors that block osteoclast fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d76602b135558c97eb922a29829b537
https://europepmc.org/articles/PMC508983/
https://europepmc.org/articles/PMC508983/
Autor:
G. D. Roodman, Brendan F. Boyce, T. A. Hentunen, Katri Selander, Hoyeon Chung, Deborah L. Galson, Noriyoshi Kurihara, Jolene J. Windle, Rowena D. Devlin, H.-R. Park, Barbara A. Koop, Sakamuri V. Reddy, S. R. Goldring, Mark Dallas
Publikováno v:
The Journal of clinical investigation. 102(1)
Cellular and molecular characterization of osteoclasts (OCL) has been extremely difficult since OCL are rare cells, and are difficult to isolate in large numbers. We used the tartrate-resistant acid phosphatase promoter to target the bcl-XL and/or Si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8cc6e2d5a69dd671fe1bc7f48c523c
https://pubmed.ncbi.nlm.nih.gov/9649561
https://pubmed.ncbi.nlm.nih.gov/9649561
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 5(11)
We report serum 25-hydroxyvitamin D (25-OHD), 24,25-dihydroxyvitamin D [24,25-(OH)2D], and 1,25-dihydroxyvitamin D [1,25-(OH)2D] levels in untreated Paget's disease and the effect of treatment with either calcitonin (CT) or etidronate (EHDP) on these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b0e50d9548a98eb0cbaa3dc918df5c
https://pubmed.ncbi.nlm.nih.gov/2125401
https://pubmed.ncbi.nlm.nih.gov/2125401