The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells

Autor: OKKENHAUG K, PATTON DT, GARCON F, ROWAN WC, VANHAESEBROECK B., BILANCIO, Antonio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3977::f32f5c2e5fc074f5d1e439b9c729d084
http://hdl.handle.net/11591/164308

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Membrane lipid composition of bronchial epithelial cells influences antiviral responses during rhinovirus infection.

Autor: Panchal MH; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK., Swindle EJ; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Institute for Life Sciences, University of Southampton, Southampton, UK., Pell TJ; GSK R&D, Stevenage, Hertfordshire, UK., Rowan WC; GSK R&D, Stevenage, Hertfordshire, UK., Childs CE; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Institute for Life Sciences, University of Southampton, Southampton, UK.; Faculty of Medicine, School of Human Development and Health, University of Southampton, Southampton, UK., Thompson J; Biomedical Imaging Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Nicholas BL; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Institute for Life Sciences, University of Southampton, Southampton, UK., Djukanovic R; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Institute for Life Sciences, University of Southampton, Southampton, UK., Goss VM; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK., Postle AD; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Institute for Life Sciences, University of Southampton, Southampton, UK., Davies DE; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Institute for Life Sciences, University of Southampton, Southampton, UK., Blume C; Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.; Institute for Life Sciences, University of Southampton, Southampton, UK.; Faculty of Medicine, School of Human Development and Health, University of Southampton, Southampton, UK.

Publikováno v: Tissue barriers [Tissue Barriers] 2024 Oct; Vol. 12 (4), pp. 2300580. Date of Electronic Publication: 2024 Jan 05.

Organ-on-chip applications in drug discovery: an end user perspective.

Autor: Clapp N; Refractory Respiratory Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Amour A; Refractory Respiratory Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Rowan WC; Novel Human Genetics Research Unit GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Candarlioglu PL; In vitro/In vivo Translation-Complex In Vitro Models, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.

Publikováno v: Biochemical Society transactions [Biochem Soc Trans] 2021 Aug 27; Vol. 49 (4), pp. 1881-1890.