Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rowan J. Ikin"'
Autor:
Amanda L. Hudson, Nicole R. Parker, Peter Khong, Jonathon F. Parkinson, Trisha Dwight, Rowan J. Ikin, Ying Zhu, Jason Chen, Helen R. Wheeler, Viive M. Howell
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
While treatment with surgery, radiotherapy and/or chemotherapy may prolong life for patients with glioblastoma, recurrence is inevitable. What is still being discovered is how much these treatments and recurrence of disease affect the molecular profi
Externí odkaz:
https://doaj.org/article/c7812e4886db453789e8b0680dda9954
Autor:
Catherine M Miller, Alana M Zakrzewski, Dionne P Robinson, Stephen J Fuller, Robert A Walker, Rowan J Ikin, Shisan J Bao, Michael E Grigg, James S Wiley, Nicholas C Smith
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129048 (2015)
BackgroundOral infection of C57BL/6J mice with the protozoan parasite Toxoplasma gondii leads to a lethal inflammatory ileitis.Principal findingsMice lacking the purinergic receptor P2X7R are acutely susceptible to toxoplasmic ileitis, losing signifi
Externí odkaz:
https://doaj.org/article/20b79e2550284248966e56543561492e
Autor:
Catherine M D Miller, Nicholas C Smith, Rowan J Ikin, Nicola R Boulter, John P Dalton, Sheila Donnelly
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5692 (2009)
BackgroundThe nature of the immune response to infection is dependent on the type of infecting organism. Intracellular organisms such as Toxoplasma gondii stimulate a Th1-driven response associated with production of IL-12, IFN-gamma, nitric oxide an
Externí odkaz:
https://doaj.org/article/b7d121ff35784a2ca8c0609324f30530
Autor:
Jonathon Parkinson, Nicole R. Parker, Helen Wheeler, Amanda Hudson, Ying Zhu, Peter Khong, Viive M. Howell, Rowan J. Ikin
Publikováno v:
Neuro-Oncology. 19:vi34-vi35
Glioblastoma, the most common and aggressive brain cancer in adults, has a very grim prognosis and a 5 year survival rate of less than 10%. While treatment with surgery, radiotherapy and/or chemotherapy may prolong life, progression is inevitable. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfc63f8538aa5f83ff5bf826bca0634
https://doi.org/10.1093/neuonc/nox168.132
https://doi.org/10.1093/neuonc/nox168.132
Autor:
Nicholas Smith, Michael P. Lees, Stephen J. Fuller, Alana M. Zakrzewski, Nicola R. Boulter, James S. Wiley, Catherine M. Miller, Rowan J. Ikin, Marilyn Katrib
Publikováno v:
International Journal for Parasitology. 41:301-308
The P2X 7 receptor (P2X 7 R) is a two transmembrane receptor that is highly expressed on the surface of immune cells. Loss of function polymorphisms in this receptor have been linked to increased susceptibility to intracellular pathogens. P2X 7 R gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a730bb63d0b9d2906e4c2a53a779c7d9
https://doi.org/10.1016/j.ijpara.2010.10.001
https://doi.org/10.1016/j.ijpara.2010.10.001
Autor:
Amanda L. Hudson, Jason J. Chen, Viive M. Howell, Zhangkai Jason Cheng, Nicole R. Parker, Ying Zhu, Rowan J. Ikin, Peter Khong, Jonathon Parkinson, Fatemeh Vafaee, Trisha Dwight, Helen Wheeler
Publikováno v:
Scientific Reports
Heterogeneity is a hallmark of glioblastoma with intratumoral heterogeneity contributing to variability in responses and resistance to standard treatments. Promoter methylation status of the DNA repair enzyme O6-methylguanine DNA methyltransferase (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c816e5c187a3b6dc097a0eb622244233
https://pubmed.ncbi.nlm.nih.gov/26940435
https://pubmed.ncbi.nlm.nih.gov/26940435
Autor:
Stephen J. Fuller, Michael E. Grigg, Rowan J. Ikin, Robert A. Walker, Dionne P. Robinson, Alana M. Zakrzewski, Catherine M. Miller, Nicholas Smith, Shisan J. Bao, James S. Wiley
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129048 (2015)
PLoS ONE
PLoS ONE
BackgroundOral infection of C57BL/6J mice with the protozoan parasite Toxoplasma gondii leads to a lethal inflammatory ileitis.Principal findingsMice lacking the purinergic receptor P2X7R are acutely susceptible to toxoplasmic ileitis, losing signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefc643a252f08fc38e8d1553228d4a1
https://doaj.org/article/20b79e2550284248966e56543561492e
https://doaj.org/article/20b79e2550284248966e56543561492e
Autor:
Zhangkai Jason Cheng, Nicole R. Parker, Rowan J. Ikin, Fatemeh Vafaee, Peter Khong, Amanda L. Hudson, Viive M. Howell, Jonathon Parkinson, Helen Wheeler
Publikováno v:
Cancer Research. 75:B39-B39
Heterogeneity is a hallmark of glioblastoma with intratumoral heterogeneity contributing to variability in responses and resistance to standard treatments. DNA repair mechanisms are key elements involved in the response to temozolomide with epigeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81eb6a18c783f75d29c2dc6286b55efa
https://doi.org/10.1158/1538-7445.brain15-b39
https://doi.org/10.1158/1538-7445.brain15-b39
Autor:
Nicholas Smith, Rowan J. Ikin, Sheila Donnelly, Catherine M. Miller, Nicola R. Boulter, John P. Dalton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 5, p e5692 (2009)
PLoS ONE, Vol 4, Iss 5, p e5692 (2009)
BackgroundThe nature of the immune response to infection is dependent on the type of infecting organism. Intracellular organisms such as Toxoplasma gondii stimulate a Th1-driven response associated with production of IL-12, IFN-gamma, nitric oxide an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc1a6d0bdbdd2b64545e4cc858738c6
https://hdl.handle.net/10453/134175
https://hdl.handle.net/10453/134175
Toxoplasma gondii is a unique intracellular parasite. It can infect a variety of cells in virtually all warm-blooded animals. It has a worldwide distribution and, overall, around one-third of people are seropositive for the parasite, with essentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f0c2c925d9dfb29b24eb8df7796718
https://hdl.handle.net/10453/8711
https://hdl.handle.net/10453/8711