Zobrazeno 1 - 10
of 614
pro vyhledávání: '"Rowan E"'
Autor:
Helen R.P. Phillips, Erin K. Cameron, Nico Eisenhauer, Victoria J. Burton, Olga Ferlian, Yiming Jin, Sahana Kanabar, Sandhya Malladi, Rowan E. Murphy, Anne Peter, Isis Petrocelli, Christian Ristok, Katharine Tyndall, Wim van der Putten, Léa Beaumelle
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110540- (2024)
Summary: Identifying the main threats to soil biodiversity is crucial as soils harbor ∼60% of global biodiversity. Many previous meta-analyses investigating the impact of different global changes (GCs) on biodiversity have omitted soil fauna or are
Externí odkaz:
https://doaj.org/article/6d543c517b7641ecac8fe93a8113151a
Autor:
James Tristan Gordy, Yinan Hui, Courtney Schill, Tianyin Wang, Fengyixin Chen, Kaitlyn Fessler, Jacob Meza, Yangchen Li, Alannah D. Taylor, Rowan E. Bates, Petros C. Karakousis, Andrew Pekosz, Jaiprasath Sachithanandham, Maggie Li, Styliani Karanika, Richard B. Markham
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPrevious studies have demonstrated enhanced efficacy of vaccine formulations that incorporate the chemokine macrophage inflammatory protein 3α (MIP-3α) to direct vaccine antigens to immature dendritic cells. To address the reduction in va
Externí odkaz:
https://doaj.org/article/708db69f8a054d40b2e5f6c712033389
Autor:
Georgina E. Wood, Christopher P. Bunting, Mesel Veli, Rupali Arora, Daniel M. Berney, Constantine Alifrangis, Nicola D. MacDonald, Rowan E. Miller, Jonathan Shamash, Sara Stoneham, Michelle Lockley
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Malignant germ cell tumours are a group of rare cancers whose incidence peaks in late adolescence and early adulthood. Dysgerminomas of the ovary and seminomas of the testis are analogous diseases, but seminomas have a 10-fold higher incidence. The t
Externí odkaz:
https://doaj.org/article/159fe2d92ec34e0787882433bc06e8f0
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Mesenchymal stem cells (MSCs) secrete paracrine factors and extracellular matrix proteins that contribute to their ability to support tissue healing and regeneration. Both the transcriptome and the secretome of MSCs can be altered
Externí odkaz:
https://doaj.org/article/7a98ce08d84749f3b4fef10857fbb8d7
Autor:
Helen Hockings, Rowan E. Miller
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
The use of PARP inhibitors (PARPi) has transformed the care of advanced high-grade serous/endometrioid ovarian cancer. PARPi are now available to patients in both the first-line and recurrent platinum-sensitive disease settings; therefore, most patie
Externí odkaz:
https://doaj.org/article/2f3bd6beb0304518a21e9504f44d4f2b
Publikováno v:
Cancers, Vol 15, Iss 19, p 4814 (2023)
Ovarian cancers are typically poorly immunogenic and have demonstrated disappointing responses to immune checkpoint inhibitor (ICI) therapy. Adoptive cellular therapy (ACT) offers an alternative method of harnessing the immune system that has shown p
Externí odkaz:
https://doaj.org/article/d6d124bbfed94ea38abb1b023a001a69
Autor:
Michael-John Devlin, Rowan E. Miller
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
The treatment of high-grade serous ovarian cancer and high-grade endometrioid ovarian cancer has seen significant improvements in recent years, with BRCA1/2 and homologous recombination status guiding a personalized approach which has resulted in imp
Externí odkaz:
https://doaj.org/article/d71dbbb9f5b24a6c92dfc8f3a3621cf6
Autor:
Rebecca Kristeleit, Juan Martin-Liberal, Kristen Spencer, Janice M Mehnert, Maria Vieito, Elizabeth J Davis, Angela Orcurto, Thomas Condamine, Daniel C Cho, Jennifer Pulini, Rowan E Miller, Sarah P Blagden, Dominik Berthold, Dana B Cardin, Prashanth Hari Dass, John E Janik, Jason Clark, Xuejun Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background OX40 is a costimulatory receptor upregulated on antigen-activated T cells and constitutively expressed on regulatory T cells (Tregs). INCAGN01949, a fully human immunoglobulin G1κ anti-OX40 agonist monoclonal antibody, was designed to pro
Externí odkaz:
https://doaj.org/article/ac1ed19fc2ac410aa1aabfc845b35fef
Publikováno v:
Ecosphere, Vol 13, Iss 2, Pp n/a-n/a (2022)
Abstract Turtles are killed on roads, yet there is little evidence of negative road effects on their abundances. We hypothesized that this could be due to reduced predation of turtle nests laid along roadsides, which could compensate for the effects
Externí odkaz:
https://doaj.org/article/4a17552079d148128851c42bbe91dc5b
Autor:
Chrispin Chaguza, Madikay Senghore, Ebrima Bojang, Rebecca A. Gladstone, Stephanie W. Lo, Peggy-Estelle Tientcheu, Rowan E. Bancroft, Archibald Worwui, Ebenezer Foster-Nyarko, Fatima Ceesay, Catherine Okoi, Lesley McGee, Keith P. Klugman, Robert F. Breiman, Michael R. Barer, Richard A. Adegbola, Martin Antonio, Stephen D. Bentley, Brenda A. Kwambana-Adams
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Streptococcus pneumoniae is an opportunistic pathogen and asymptomatic colonization is a precursor for invasive disease. Here the authors show rapid within-host evolution of naturally acquired pneumococci in ninety-eight infants driven by high nucleo
Externí odkaz:
https://doaj.org/article/0e98e6e6394d47f4b1f34dfd27a30caf