Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with Covid-19. A randomized clinical trial

Autor: Lawler, P.R., Derde, L.P.G., Veerdonk, F.L. van de, McVerry, B.J., Huang, D.T., Berry, L.R., Lorenzi, E., Kimmenade, R.R.J. van, Gommans, F., Vaduganathan, M., Leaf, D.E., Baron, R.M., Kim, E.Y., Frankfurter, C., Epelman, S., Kwan, Y., Grieve, R., O'Neill, S., Sadique, Z., Puskarich, M., Marshall, J.C., Higgins, A.M., Mouncey, P.R., Rowan, K.M., Al-Beidh, F., Annane, D., Arabi, Y.M., Au, C., Beane, A., Bentum-Puijk, W. van, Bonten, M.J.M., Bradbury, C.A., Brunkhorst, F.M., Burrell, A., Buzgau, A., Buxton, M., Cecconi, M., Cheng, A.C., Cove, M., Detry, M.A., Estcourt, L.J., Ezekowitz, J., Fitzgerald, M., Gattas, D., Godoy, L.C., Goossens, H., Haniffa, R., Harrison, D.A., Hills, T., Horvat, C.M., Ichihara, N., Lamontagne, F., Linstrum, K.M., McAuley, D.F., McGlothlin, A., McGuinness, S.P., McQuilten, Z., Murthy, S., Nichol, A.D., Owen, D.R.J., Parke, R.L., Parker, J.C., Pollock, K.M., Reyes, L.F., Saito, H., Santos, M.S., Saunders, C.T., Seymour, C.W., Shankar-Hari, M., Singh, V., Turgeon, A.F., Turner, A.M., Zarychanski, R., Green, C., Lewis, R.J., Angus, D.C., Berry, S., Gordon, A.C., McArthur, C.J., Webb, S.A.

Publikováno v: Lawler, P R, Derde, L P G, Van De Veerdonk, F L, McVerry, B J, Huang, D T, Berry, L R, Lorenzi, E, Van Kimmenade, R, Gommans, F, Vaduganathan, M, Leaf, D E, Baron, R M, Kim, E Y, Frankfurter, C, Epelmaņ, S, Kwan, Y, Grieve, R, O'Neill, S, Sadique, Z, Puskarich, M, Marshall, J C, Higgins, A M, Mouncey, P R, Rowan, K M, Al-Beidh, F, Annane, D, Arabi, Y M, Au, C, Beane, A, Van Bentum-Puijk, W, Bonten, M J M, Bradbury, C A, Brunkhorst, F M, Burrell, A, Buzgau, A, Buxton, M, Cecconi, M, Cheng, A C, Cove, M, Detry, M A, Estcourt, L J, Ezekowitz, J, Fitzgerald, M, Gattas, D, Godoy, L C, Goossens, H, Haniffa, R, Harrison, D A, Hills, T, Horvat, C M, Ichihara, N, Lamontagne, F, Linstrum, K M, McAuley, D F, McGlothlin, A, McGuinness, S P, McQuilten, Z, Murthy, S, Nichol, A D, Owen, D R J, Parke, R L, Parker, J C, Pollock, K M, Reyes, L F, Saito, H, Santos, M S, Saunders, C T, Seymour, C W, Shankar-Hari, M, Singh, V, Turgeon, A F, Turner, A M, Zarychanski, R, Green, C, Lewis, R J, Angus, D C, Berry, S, Gordon, A C, McArthur, C J & Webb, S A 2023, ' Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with Covid-19. A randomized clinical trial ', JAMA, vol. 329, no. 14, pp. 1183-1196 . https://doi.org/10.1001/jama.2023.4480
Jama : Journal of the American Medical Association, 329, 14, pp. 1183-1196
Jama : Journal of the American Medical Association, 329, 1183-1196

Contains fulltext : 291878.pdf (Publisher’s version ) (Closed access) IMPORTANCE: Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. OBJECTIVE: To determine whether angiotensin-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8ff6a211c4c42dc02259195c83981b0d
https://pure.qub.ac.uk/en/publications/8cae3556-8039-49ea-a414-6da1b5a01052

An Integrated Approach to Evaluating Alternative Risk Prediction Strategies: A Case Study Comparing Alternative Approaches for Preventing Invasive Fungal Disease

Autor: Sadique, Z., Grieve, R., Harrison, D.A., Jit, M., Allen, E., Rowan, K.M.

Publikováno v: In Value in Health December 2013 16(8):1111-1122

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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

Autor: Gordon, A.C., Mouncey, P.R., Al-Beidh, F., Rowan, K.M., Nichol, A.D., Arabi, Y.M., Annane, D., Beane, A., Bentum-Puijk, W. van, Berry, L.R., Bhimani, Z., Bonten, M.J.M., Bradbury, C.A., Brunkhorst, F.M., Buzgau, A., Cheng, A.C., Detry, M.A., Duffy, E.J., Estcourt, L.J., Fitzgerald, M., Goossens, H., Haniffa, R., Higgins, A.M., Hills, T.E., Horvat, C.M., Lamontagne, F., Lawler, P.R., Leavis, H.L., Linstrum, K.M., Litton, E., Lorenzi, E., Marshall, J.C., Mayr, F.B., McAuley, D.F., McGlothlin, A., McGuinness, S.P., McVerry, B.J., Montgomery, S.K., Morpeth, S.C., Murthy, S., Orr, K., Parke, R.L., Parker, J.C., Patanwala, A.E., Pettilä, V., Rademaker, E., Santos, M.S., Saunders, C.T., Seymour, C.W., Shankar-Hari, M., Sligl, W.I., Turgeon, A.F., Turner, A.M., Veerdonk, F.L. van de, Zarychanski, R., Green, C., Lewis, R.J., Angus, D.C., McArthur, C.J., Berry, S., Schouten, J.A., Pickkers, P., Webb, S.A., Derde, L.P.G.

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2021, 384 (16), pp.1491-1502. ⟨10.1056/NEJMoa2100433⟩
McAuley, D & Writing Committee, REMAP-CAP 2021, ' Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 ', New England Journal of Medicine . https://doi.org/10.1056/NEJMoa2100433
2021, ' Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 ', New England Journal of Medicine, vol. 384, no. 16, pp. 1491-1502 . https://doi.org/10.1056/NEJMoa2100433
The New England Journal of Medicine, 384, 16, pp. 1491-1502
The New England Journal of Medicine, 384, 1491-1502
NEW ENGLAND JOURNAL OF MEDICINE
REMAP-CAP Investigators, Felton, T & Dark, P 2021, ' Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 ', The New England Journal of Medicine, vol. 384, no. 16, pp. 1491-1502 . https://doi.org/10.1056/NEJMoa2100433
The New England Journal of Medicine

BACKGROUNDThe efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear.METHODSWe evaluated tocilizumab and sarilumab in an ongoing international, multifactorial, adaptive platform t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a842cc61a154327cc1bed7cc2b37f04
https://pubmed.ncbi.nlm.nih.gov/34920865

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