Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Rowaida Z. Taha"'
Autor:
Yasser Al-Sarraj, Rowaida Z. Taha, Eman Al-Dous, Dina Ahram, Somayyeh Abbasi, Eman Abuazab, Hibah Shaath, Wesal Habbab, Khaoula Errafii, Yosra Bejaoui, Maryam AlMotawa, Namat Khattab, Yasmin Abu Aqel, Karim E. Shalaby, Amina Al-Ansari, Marios Kambouris, Adel Abouzohri, Iman Ghazal, Mohammed Tolfat, Fouad Alshaban, Hatem El-Shanti, Omar M. E. Albagha
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Autism spectrum disorder (ASD) is characterized by aberrations in social interaction and communication associated with repetitive behaviors and interests, with strong clinical heterogeneity. Genetic factors play an important role in ASD
Externí odkaz:
https://doaj.org/article/1cb66fb1f0d64cfb9ab254e423381745
Autor:
Nuha T. Swaidan, Nada H. Soliman, Ahmed T. Aboughalia, Toqa Darwish, Ruba O. Almeshal, Azhar A. Al-Khulaifi, Rowaida Z. Taha, Rania Alanany, Ahmed Y. Hussein, Salam Salloum-Asfar, Sara A. Abdulla, Abdallah M. Abdallah, Mohamed M. Emara
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Reprogramming human somatic cells into a pluripotent state, achieved through the activation of well-defined transcriptional factors known as OSKM factors, offers significant potential for regenerative medicine. While OSKM factors are a robust reprogr
Externí odkaz:
https://doaj.org/article/3afa19d27b0f491590abfc71c2b647a5
Publikováno v:
Epigenetics, Vol 15, Iss 12, Pp 1275-1288 (2020)
Myeloid cells, including antigen-presenting cells (APCs) and myeloid-derived suppressor cells (MDSCs) play opposing roles to orchestrate innate and adaptive immune responses during physiological and pathological conditions. We investigated the role o
Externí odkaz:
https://doaj.org/article/4c40685c412d4c408176ec25a561463d
Publikováno v:
Cells, Vol 11, Iss 23, p 3833 (2022)
Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem cells. However, this process
Externí odkaz:
https://doaj.org/article/39c4c427f4f94eb58e7f671008663588
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background Colorectal cancer (CRC) is the third most commonly diagnosed human malignancy worldwide. Upregulation of inhibitory immune checkpoints by tumor-infiltrating immune cells (TIICs) or their ligands by tumor cells leads to tumor evasi
Externí odkaz:
https://doaj.org/article/5ca19e7e112c40708bf9e13d471ae9ef
Autor:
Varun Sasidharan Nair, Haytham El Salhat, Rowaida Z. Taha, Anne John, Bassam R. Ali, Eyad Elkord
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background High expression of immune checkpoints in tumor microenvironment plays significant roles in inhibiting anti-tumor immunity, which is associated with poor prognosis and cancer progression. Major epigenetic modifications in both DNA
Externí odkaz:
https://doaj.org/article/e693adf168e0439da6dcb29e72aa7fa4
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Aberrant expression of immune checkpoints (ICs) in cancer creates an immunosuppressive microenvironment, which supports immune evasion of tumor cells. We have recently reported that epigenetic modifications are critical for ICs expression in the tumo
Externí odkaz:
https://doaj.org/article/5f33d495f03d4c2eba37d44be03ceac2
Autor:
Salman M. Toor, Varun Sasidharan Nair, Reem Saleh, Rowaida Z. Taha, Khaled Murshed, Mahmood Al-Dhaheri, Mahwish Khawar, Ayman A. Ahmed, Mohamed A. Kurer, Mohamed Abu Nada, Eyad Elkord
Publikováno v:
Vaccines, Vol 9, Iss 4, p 334 (2021)
Colorectal cancer (CRC) is influenced by infiltration of immune cell populations in the tumor microenvironment. While elevated levels of cytotoxic T cells are associated with improved prognosis, limited studies have reported associations between CD4+
Externí odkaz:
https://doaj.org/article/4257ce918dc648b3b2e7bbbb6d0bb0dc
Autor:
Varun Sasidharan Nair, Mohamed Abu Nada, Khaled Murshed, Salman M Toor, Rowaida Z. Taha, Eyad Elkord, Mohamed A Kurer, Reem Saleh, Ayman A. Ahmed
Publikováno v:
Epigenomics. 12:1871-1882
Aim: To elucidate the epigenetic alterations behind the upregulation of immune checkpoints and T cell exhaustion markers in colorectal cancer (CRC) patients. Materials & methods: mRNA expressions of different immune checkpoint/exhaustion markers were
Autor:
Rowaida Z. Taha, Mohammed Tolfat, Dina Ahram, Omar M. E. Albagha, Fouad Alshaban, Yasser Al-Sarraj, Eman K. Al-Dous, Hatem El-Shanti
Publikováno v:
Genes
Volume 12
Issue 5
Genes, Vol 12, Iss 761, p 761 (2021)
Volume 12
Issue 5
Genes, Vol 12, Iss 761, p 761 (2021)
Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by abnormalities in language and social communication with substantial clinical heterogeneity. Genetic factors play an important role in ASD with heritability estimated betw