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CDK5RAP3, a New BRCA2 Partner That Regulates DNA Repair, Is Associated with Breast Cancer Survival

Autor: Minguillón, Jordi, Ramírez, María José, Rovirosa, Llorenç, Bustamante Madrid, Pilar, Camps Fajol, Cristina, Ruiz de Garibay, Gorka, Shimelis, Hermela, Montanuy, Helena, Pujol, Roser, Hernandez, Gonzalo, Bogliolo, Massimo, Castillo, Pau, Soucy, Penny, Martrat, Griselda, Gómez, Antonio, Cuadras, Daniel, García, María J., Gayarre, Javier, Lázaro, Conxi, Benítez, Javier, Couch, Fergus J., Pujana, Miquel Angel, Surrallés, Jordi, CIMBA Consortium

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Cancers; Volume 14; Issue 2; Pages: 353
Cancers, Vol 14, Iss 353, p 353 (2022)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Cancers
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Simple Summary BRCA2 is an essential gene for DNA repair by homologous recombination and is often mutated in families at risk of breast and ovarian cancer. In this study we identified CDK5RAP3 tumor suppressor as a new BRCA2-interacting protein. CDK5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1def6fdd77514bd7fc23bc7a77f6a6b
http://hdl.handle.net/2445/183778

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CDK5RAP3, a New BRCA2 Partner That Regulates DNA Repair, Is Associated with Breast Cancer Survival.

Autor: Minguillón J; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Ramírez MJ; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Rovirosa L; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Bustamante-Madrid P; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Camps-Fajol C; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Ruiz de Garibay G; Program against Cancer Therapeutic Resistance (ProCURE), Breast Cancer and Systems Biology, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Spain., Shimelis H; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55901, USA.; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55901, USA., Montanuy H; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Pujol R; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Hernandez G; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Bogliolo M; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Castillo P; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, QC G1E 6W2, Canada., Martrat G; Program against Cancer Therapeutic Resistance (ProCURE), Breast Cancer and Systems Biology, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Spain., Gómez A; Cancer Epigenetics and Biology Program, Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Spain., Cuadras D; Program against Cancer Therapeutic Resistance (ProCURE), Breast Cancer and Systems Biology, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Spain., García MJ; Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Gayarre J; Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Cimba, Lázaro C; Hereditary Cancer Program, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Spain., Benítez J; Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55901, USA.; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55901, USA., Pujana MA; Program against Cancer Therapeutic Resistance (ProCURE), Breast Cancer and Systems Biology, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Spain., Surrallés J; Genomic Instability Syndromes and DNA Repair Group and Join Research Unit on Genomic Medicine UAB-Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER) U-745, 08041 Barcelona, Spain.

Publikováno v: Cancers [Cancers (Basel)] 2022 Jan 12; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 12.