Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rouven Schulz"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-26 (2022)
Understanding the function of GPCRs requires stimulation with their specific ligands. Here, the authors design chemogenetic G-protein coupled receptors that allows for the study of receptors without knowing the immediate ligand, and demonstrate its u
Externí odkaz:
https://doaj.org/article/def374d422f9470181b7fdef4cf795a2
Autor:
Irina Tsymala, Magdalini Nigritinou, Bleranda Zeka, Rouven Schulz, Felix Niederschick, Mia Matković, Isabel J. Bauer, Michael Szalay, Kathrin Schanda, Magdalena Lerch, Tatsuro Misu, Kazuo Fujihara, Jeffrey L. Bennett, Charlotte Dahle, Florence Pache, Paulus Rommer, Fritz Leutmezer, Zsolt Illes, Maria Isabel Leite, Jacqueline Palace, Petra Scholze, Markus Reindl, Hans Lassmann, Monika Bradl
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Most cases of neuromyelitis optica spectrum disorders (NMOSD) harbor pathogenic autoantibodies against the water channel aquaporin 4 (AQP4). Binding of these antibodies to AQP4 on astrocytes initiates damage to these cells, which culminates
Externí odkaz:
https://doaj.org/article/31f94705aa8441cd9a1d41acfcb1be81
Autor:
Gloria Colombo, Ryan John A. Cubero, Lida Kanari, Alessandro Venturino, Rouven Schulz, Martina Scolamiero, Jens Agerberg, Hansruedi Mathys, Li-Huei Tsai, Wojciech Chachólski, Kathryn Hess, Sandra Siegert
Publikováno v:
Nature neuroscience. 25(10)
Environmental cues influence the highly dynamic morphology of microglia. Strategies to characterize these changes usually involve user-selected morphometric features, which preclude the identification of a spectrum of context-dependent morphological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330d2ee5405cdda8d211430c7d210e64
https://pubmed.ncbi.nlm.nih.gov/36180790
https://pubmed.ncbi.nlm.nih.gov/36180790
Autor:
Medina KORKUT-DEMIRBAŞ, Gloria Colombo, Sandra Dr. Siegert, Rouven Schulz, Alessandro Venturino
Publikováno v:
Nature communications. 13(1)
G protein-coupled receptors (GPCRs) regulate processes ranging from immune responses to neuronal signaling. However, ligands for many GPCRs remain unknown, suffer from off-target effects or have poor bioavailability. Additionally, dissecting cell typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092ba07e913dd86890a67b3461f26917
https://pubmed.ncbi.nlm.nih.gov/35970889
https://pubmed.ncbi.nlm.nih.gov/35970889
G protein-coupled receptors (GPCRs) regulate multiple processes ranging from cell growth and immune responses to neuronal signal transmission. However, ligands for many GPCRs remain unknown, suffer from off-target effects or have poor bioavailability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9137412fff4ad6ca94825e2469c6a12
https://doi.org/10.1101/2021.06.21.449162
https://doi.org/10.1101/2021.06.21.449162
Autor:
Monika Bradl, Maria Isabel Leite, Markus Reindl, Felix Niederschick, Michael Szalay, Magdalini Nigritinou, Hans Lassmann, Kazuo Fujihara, Irina Tsymala, Fritz Leutmezer, Bleranda Zeka, Rouven Schulz, Tatsuro Misu, Florence Pache, Mia Matković, Kathrin Schanda, Jeffrey Bennett, Petra Scholze, Isabel J. Bauer, Zsolt Illes, Jacqueline Palace, Magdalena Lerch, Charlotte Dahle, Paulus S. Rommer
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Tsymala, I, Nigritinou, M, Zeka, B, Schulz, R, Niederschick, F, Matković, M, Bauer, I J, Szalay, M, Schanda, K, Lerch, M, Misu, T, Fujihara, K, Bennett, J L, Dahle, C, Pache, F, Rommer, P, Leutmezer, F, Illes, Z, Leite, M I, Palace, J, Scholze, P, Reindl, M, Lassmann, H & Bradl, M 2020, ' Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes ', Acta Neuropathologica Communications, vol. 8, 49 . https://doi.org/10.1186/s40478-020-00920-x
Acta Neuropathologica Communications
Tsymala, I, Nigritinou, M, Zeka, B, Schulz, R, Niederschick, F, Matković, M, Bauer, I J, Szalay, M, Schanda, K, Lerch, M, Misu, T, Fujihara, K, Bennett, J L, Dahle, C, Pache, F, Rommer, P, Leutmezer, F, Illes, Z, Leite, M I, Palace, J, Scholze, P, Reindl, M, Lassmann, H & Bradl, M 2020, ' Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes ', Acta Neuropathologica Communications, vol. 8, 49 . https://doi.org/10.1186/s40478-020-00920-x
Acta Neuropathologica Communications
Most cases of neuromyelitis optica spectrum disorders (NMOSD) harbor pathogenic autoantibodies against the water channel aquaporin 4 (AQP4). Binding of these antibodies to AQP4 on astrocytes initiates damage to these cells, which culminates in the fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3029b5cb9af1734a2af011c5bf64c7
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-173523
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-173523
Autor:
Margaret E. Maes, Ryan John Cubero, Gloria Colombo, Florianne E. Schoot Uiterkamp, Sandra Siegert, Bálint Nagy, Mark F. Bear, Alessandro Venturino, Héctor De Jesús-Cortés, Francis Reilly-Andújar, Rouven Schulz
Publikováno v:
Cell Reports
Cell Rep
Cell Rep
Perineuronal nets (PNNs), components of the extracellular matrix, preferentially coat parvalbumin-positive interneurons and constrain critical-period plasticity in the adult cerebral cortex. Current strategies to remove PNN are long-lasting, invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5df0b2b071586c7d45e8a3fcf5b7b0
https://doi.org/10.1016/j.celrep.2021.109313
https://doi.org/10.1016/j.celrep.2021.109313
Publikováno v:
Neuroscience Letters
Highlights • Background of lentiviral and adeno-associated virus vector design. • Reviewing of literature that reported in vivo microglial transduction. • Challenges to overcome low microglial transduction efficiency and specificity. • Guidel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160af25a32ef86b7776ea735f778e592