Title: Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion

Autor: Pedreira De Freitas Nader, Guilherme, Agüera-Gonzalez, Sonia, Routet, Fiona, Gratia, Matthieu, Maurin, Mathieu, Cancila, Valeria, Cadart, Clotilde, Palamidessi, Andrea, Ramos, Rodrigo, San, Mabel, Gentili, Matteo, Yamada, Ayako, Williart, Alice, Lodillinsky, Catalina, Lagoutte, Emilie, Villard, Catherine, Viovy, Jean-Louis, Tripodo, Claudio, Galon, Jérôme, Scita, Giorgio, Manel, Nicolas, Chavrier, Philippe, Piel, Matthieu

Publikováno v: Cell
Cell, Cell Press Elsevier, 2021

International audience; While mutations leading to a compromised nuclear envelope cause diseases such as muscular dystrophies or accelerated aging, the consequences of mechanically induced nuclear envelope ruptures are less known. Here we show that n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aa6d41020c7a1cf5638e68571fa7c7bb
https://hal.archives-ouvertes.fr/hal-03392287/document

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Optogenetic Light Sensors in Human Retinal Organoids

Autor: Garita-Hernandez, Marcela, Guibbal, Laure, Toualbi, Lyes, Routet, Fiona, Chaffiol, Antoine, Winckler, Céline, Harinquet, Marylin, Robert, Camille, Fouquet, Stéphane, Bellow, Sébastien, Sahel, José-Alain, Goureau, Olivier, Duebel, Jens, Dalkara, Deniz

Publikováno v: Frontiers in Neuroscience
Frontiers in Neuroscience, Frontiers, 2018, 12, pp.789. ⟨10.3389/fnins.2018.00789⟩

International audience; Optogenetic technologies paved the way to dissect complex neural circuits and monitor neural activity using light in animals. In retinal disease, optogenetics has been used as a therapeutic modality to reanimate the retina aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::18875586197820057b091217715c3542

L’actualité immunologique sous l’oeil critique des étudiants de Master 2. (French)

Autor: Arnaud, Marine, Belhedi, Skander, Dréan, Raphaëlle, Herrag, Mounia, Renaud, Marion, Routet, Fiona, Trilleaud, Charlène

Publikováno v: Médecine Sciences; apr2016, Vol. 32 Issue 4, p348-351, 4p

Restoration of visual function by transplantation of optogenetically engineered photoreceptors

Autor: Garita-Hernandez, Marcela, Lampič, Maruša, Chaffiol, Antoine, Guibbal, Laure, Routet, Fiona, Santos-Ferreira, Tiago, Gasparini, Sylvia, Borsch, Oliver, Gagliardi, Giuliana, Reichman, Sacha, Picaud, Serge, Sahel, José-Alain, Goureau, Olivier, Ader, Marius, Dalkara, Deniz, Duebel, Jens

Publikováno v: Nature Communications
Nature Communications, 2019, 10 (1), pp.4524. ⟨10.1038/s41467-019-12330-2⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.4524. ⟨10.1038/s41467-019-12330-2⟩
Nature Communications, 10, 4524
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, 10, 1, pp. 4524

A major challenge in the treatment of retinal degenerative diseases, with the transplantation of replacement photoreceptors, is the difficulty in inducing the grafted cells to grow and maintain light sensitive outer segments in the host retina, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7d7189c335e476236f7551ef23dffccf