The administration of the synthetic peptide YMESRADR with a low aspirin dose significantly augments its antiplatelet effect, in contrast to the highly constrained peptide (S,S) PSRCDCR-NH 2 . An experimental study.

Autor: Englezopoulos KV; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece. Electronic address: cenglezopoulos@gmail.com., Stathopoulou EM; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Moussis V; Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Chantzichristos VG; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Papamichael ND; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece., Tatsidou PT; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Roussa VD; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece., Tsoumani ME; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Lakkas L; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece., Rammos A; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece., Katsouras CS; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece., Fotou E; Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Tsikaris V; Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Tselepis AD; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Michalis LK; B Department of Cardiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece.

Publikováno v: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese [Hellenic J Cardiol] 2022 May-Jun; Vol. 65, pp. 56-58. Date of Electronic Publication: 2022 Jan 29.

Effect of a synthetic peptide corresponding to residues 313 to 320 of the alphaIIb subunit of the human platelet integrin alphaIIbbeta3 on carotid artery thrombosis in rabbits.

Autor: Papamichael ND; Medical School, Department of Cardiology, University of Ioannina, Ioannina, Greece., Stathopoulou EM, Roussa VD, Tsironis LD, Kotsia AP, Stanica RM, Moussis V, Tsikaris V, Katsouras CS, Tselepis AD, Michalis LK

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2009 May; Vol. 329 (2), pp. 634-40. Date of Electronic Publication: 2009 Feb 24.