Zobrazeno 1 - 10 of 136 pro vyhledávání: '"Rousel J"'
1
Akademický článek
Lesional Psoriasis is Associated With Alterations in the Stratum Corneum Ceramide Profile and Concomitant Decreases in Barrier Function.
Autor: Rousel J; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Mergen C; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Bergmans ME; Centre for Human Drug Research, Leiden, The Netherlands.; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands., Klarenbeek NB; Centre for Human Drug Research, Leiden, The Netherlands., der Kolk TN; Centre for Human Drug Research, Leiden, The Netherlands., van Doorn MBA; Centre for Human Drug Research, Leiden, The Netherlands.; Department of Dermatology, Erasmus Medical Centre, Rotterdam, The Netherlands., Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Rissmann R; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
Publikováno v: Experimental dermatology [Exp Dermatol] 2024 Oct; Vol. 33 (10), pp. e15185.
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2
Report
Similar Alterations of the Stratum Corneum Ceramide Profile in Atopic Dermatitis, Psoriasis, and Ichthyosis: Results from a Systematic Review and Meta-Analysis.
Autor: Rousel J; Centre for Human Drug Research (CHDR), Leiden, The Netherlands; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Mergen C; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Schoones JW; Directorate of Research Policy, Leiden University Medical Centre, Leiden, The Netherlands., Niemeyer-van der Kolk T; Centre for Human Drug Research (CHDR), Leiden, The Netherlands., van Doorn MBA; Centre for Human Drug Research (CHDR), Leiden, The Netherlands; Department of Dermatology, Erasmus Medical Centre, Rotterdam, The Netherlands., Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., van Smeden J; Centre for Human Drug Research (CHDR), Leiden, The Netherlands; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, The Netherlands., Rissmann R; Centre for Human Drug Research (CHDR), Leiden, The Netherlands; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Department of Dermatology, Leiden University Medical Centre, Leiden, The Netherlands. Electronic address: rrissmann@chdr.nl.
Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2024 Oct; Vol. 144 (10), pp. 2311-2314.e22. Date of Electronic Publication: 2024 Mar 04.
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3
Akademický článek
Guselkumab treatment normalizes the stratum corneum ceramide profile and alleviates barrier dysfunction in psoriasis: results of a randomized controlled trial.
Autor: Rousel J; Centre for Human Drug Research, Leiden, The Netherlands; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Mergen C; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Bergmans ME; Centre for Human Drug Research, Leiden, The Netherlands; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands., Bruijnincx LJ; Centre for Human Drug Research, Leiden, The Netherlands., de Kam ML; Centre for Human Drug Research, Leiden, The Netherlands., Klarenbeek NB; Centre for Human Drug Research, Leiden, The Netherlands., Niemeyer-van der Kolk T; Centre for Human Drug Research, Leiden, The Netherlands., van Doorn MBA; Centre for Human Drug Research, Leiden, The Netherlands; Department of Dermatology, Erasmus Medical Centre, Rotterdam, The Netherlands., Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Rissmann R; Centre for Human Drug Research, Leiden, The Netherlands; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: rrissmann@chdr.nl.
Publikováno v: Journal of lipid research [J Lipid Res] 2024 Aug; Vol. 65 (8), pp. 100591. Date of Electronic Publication: 2024 Jul 09.
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4
Akademický článek
Lesional skin of seborrheic dermatitis patients is characterized by skin barrier dysfunction and correlating alterations in the stratum corneum ceramide composition.
Autor: Rousel J; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Nădăban A; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Saghari M; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands., Pagan L; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands., Zhuparris A; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.; Leiden Institute of Advanced Computer Science, Leiden University, Leiden, Netherlands., Theelen B; Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands., Gambrah T; Centre for Human Drug Research, Leiden, The Netherlands., van der Wall HEC; Centre for Human Drug Research, Leiden, The Netherlands., Vreeken RJ; Maastricht Multimodal Molecular Imaging Institute, Maastricht University, Maastricht, The Netherlands., Feiss GL; Cutanea Life Sciences, Wayne, Pennsylvania, USA., Niemeyer-van der Kolk T; Centre for Human Drug Research, Leiden, The Netherlands., Burggraaf J; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands., van Doorn MBA; Centre for Human Drug Research, Leiden, The Netherlands.; Department of Dermatology, Erasmus Medical Centre, Rotterdam, The Netherlands., Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Rissmann R; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.
Publikováno v: Experimental dermatology [Exp Dermatol] 2024 Jan; Vol. 33 (1), pp. e14952. Date of Electronic Publication: 2023 Nov 16.
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5
Akademický článek
Guselkumab induction therapy demonstrates long-lasting efficacy in patients with mild psoriasis, results from a randomized, placebo-controlled exploratory clinical trial.
Autor: Rousel J; Centre for Human Drug Research, Leiden, The Netherlands; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Bergmans ME; Centre for Human Drug Research, Leiden, The Netherlands; Leiden University Medical Center, Leiden, The Netherlands., van der Meulen LWJ; Centre for Human Drug Research, Leiden, The Netherlands; Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Pagan L; Centre for Human Drug Research, Leiden, The Netherlands; Leiden University Medical Center, Leiden, The Netherlands., de Bruin DT; Centre for Human Drug Research, Leiden, The Netherlands; Leiden University Medical Center, Leiden, The Netherlands., de Kam ML; Centre for Human Drug Research, Leiden, The Netherlands., Klarenbeek NB; Centre for Human Drug Research, Leiden, The Netherlands., Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Seyger MMB; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands., van den Reek JMPA; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands., Niemeyer-van der Kolk T; Centre for Human Drug Research, Leiden, The Netherlands., Rissmann R; Centre for Human Drug Research, Leiden, The Netherlands; Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Leiden University Medical Center, Leiden, The Netherlands. Electronic address: rrissmann@chdr.nl., van Doorn MBA; Centre for Human Drug Research, Leiden, The Netherlands; Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Publikováno v: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2024 Feb; Vol. 90 (2), pp. 395-397. Date of Electronic Publication: 2023 Oct 05.
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6
Akademický článek
The effect of PPAR isoform (de)activation on the lipid composition in full-thickness skin models.
Autor: Helder RWJ; Division of Biotherapeutics, LACDR, Leiden University, Leiden, The Netherlands., Rousel J; Division of Biotherapeutics, LACDR, Leiden University, Leiden, The Netherlands., Boiten WA; Division of Biotherapeutics, LACDR, Leiden University, Leiden, The Netherlands., Gooris GS; Division of Biotherapeutics, LACDR, Leiden University, Leiden, The Netherlands., Nadaban A; Division of Biotherapeutics, LACDR, Leiden University, Leiden, The Netherlands., El Ghalbzouri A; Department of Dermatology, LUMC, Leiden, The Netherlands., Bouwstra JA; Division of Biotherapeutics, LACDR, Leiden University, Leiden, The Netherlands.
Publikováno v: Experimental dermatology [Exp Dermatol] 2023 Apr; Vol. 32 (4), pp. 469-478. Date of Electronic Publication: 2023 Jan 02.
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7
Akademický článek
Treatment with the Topical Antimicrobial Peptide Omiganan in Mild-to-Moderate Facial Seborrheic Dermatitis versus Ketoconazole and Placebo: Results of a Randomized Controlled Proof-of-Concept Trial.
Autor: Rousel J; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., Saghari M; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands.; Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands., Pagan L; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands.; Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands., Nădăban A; Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., Gambrah T; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands., Theelen B; Westerdijk Fungal Biodiversity Institute, 3508 AD Utrecht, The Netherlands., de Kam ML; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands., Haakman J; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands., van der Wall HEC; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands., Feiss GL; Cutanea Life Sciences, Wayne, PA 19087, USA., Niemeyer-van der Kolk T; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands., Burggraaf J; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.; Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands., Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., Rissmann R; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.; Leiden University Medical Center, Leiden University, 2333 ZA Leiden, The Netherlands., van Doorn MBA; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands.; Department of Dermatology, Erasmus Medical Centre, 3015 GD Rotterdam, The Netherlands.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 20; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 20.
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8
Akademický článek
Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models.
Autor: Nădăban A; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Rousel J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Centre for Human Drug Research, Leiden, The Netherlands., El Yachioui D; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Gooris GS; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Beddoes CM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Dalgliesh RM; ISIS Neutron and Muon Source, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Didcot, United Kingdom., Malfois M; ALBA Synchrotron, Barcelona, Spain., Rissmann R; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Centre for Human Drug Research, Leiden, The Netherlands; Leiden University Medical Center, Leiden, The Netherlands., Bouwstra JA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands. Electronic address: bouwstra@lacdr.leidenuniv.nl.
Publikováno v: Journal of lipid research [J Lipid Res] 2023 Aug; Vol. 64 (8), pp. 100400. Date of Electronic Publication: 2023 Jun 08.
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