Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Roumen Voutev"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009460 (2021)
Visual perception of the environment is mediated by specialized photoreceptor (PR) neurons of the eye. Each PR expresses photosensitive opsins, which are activated by a particular wavelength of light. In most insects, the visual system comprises a pa
Externí odkaz:
https://doaj.org/article/baf113dc68824bf98ae75a7cb72c4a97
Autor:
Carlos Sánchez-Higueras, Chaitanya Rastogi, Roumen Voutev, Harmen J. Bussemaker, Richard S. Mann, James C.-G. Hombría
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Hox proteins are expressed in partially overlapping regions to inform development along the embryo’s head-tail axis. Here the authors analyse a cis regulatory module directly regulated by seven different Drosophila Hox proteins to uncover how diffe
Externí odkaz:
https://doaj.org/article/33fa56c7633f40faac90d12b3fc513f9
Autor:
Roumen Voutev, Richard S. Mann
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 4, Pp 983-986 (2019)
Molecular biology techniques have a large impact on biomedical research and the availability of diverse tools to perform genome manipulations advances the ease of executing complicated genetic research. Here, we introduce in the fruit fly another suc
Externí odkaz:
https://doaj.org/article/317404a6d93945a999d780a8c314c413
Autor:
Roumen Voutev, Richard S. Mann
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 5, Pp 1399-1402 (2018)
Effective genome engineering should lead to a desired locus change with minimal adverse impact to the genome itself. However, flanking loci with site-directed recombinase recognition sites, such as those of the phage ΦC31 integrase, allows for creat
Externí odkaz:
https://doaj.org/article/9c947d5b97d74a8fa9582c85dd75ef2f
Publikováno v:
PLoS Genetics, Vol 15, Iss 10, p e1008444 (2019)
Specification of cell identity and the proper functioning of a mature cell depend on precise regulation of gene expression. Both binary ON/OFF regulation of transcription, as well as more fine-tuned control of transcription levels in the ON state, ar
Externí odkaz:
https://doaj.org/article/fced7344fe9948c791a59c270ed4381c
Autor:
Roumen Voutev, Richard S. Mann
Publikováno v:
BioTechniques, Vol 60, Iss 3, Pp 141-144 (2016)
Enhancer elements in most eukaryotic organisms are often positioned at a great distance away from the transcription start site of the gene they regulate. Complex three-dimensional chromatin organization and insulators usually guide and limit the rang
Externí odkaz:
https://doaj.org/article/7af276018953464db564dbd595b319da
Autor:
Susan Newcomb, Roumen Voutev, Aurelie Jory, Rebecca K Delker, Matthew Slattery, Richard S Mann
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007568 (2018)
We characterized the establishment of an Epidermal Growth Factor Receptor (EGFR) organizing center (EOC) during leg development in Drosophila melanogaster. Initial EGFR activation occurs in the center of leg discs by expression of the EGFR ligand Vn
Externí odkaz:
https://doaj.org/article/c424da00ca2643108f3459c20985febe
Autor:
Roumen Voutev, Richard S. Mann
Publikováno v:
BioTechniques, Vol 62, Iss 1, Pp 37-38 (2017)
Rapid and reliable genome modifications provide the basis for detailed in vivo functional analysis of any genomic entity (gene, regulatory DNA, non-coding RNA, etc). With the advent of CRISPR/Cas9 genome editing technology, manipulation of a particul
Externí odkaz:
https://doaj.org/article/96d55635dd7b4ae2b23bf0f0ae7701a4
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003753 (2013)
The Yorkie/Yap transcriptional coactivator is a well-known regulator of cellular proliferation in both invertebrates and mammals. As a coactivator, Yorkie (Yki) lacks a DNA binding domain and must partner with sequence-specific DNA binding proteins i
Externí odkaz:
https://doaj.org/article/f8d8fde1bf5f4ccf9fdaf520f2111aed
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 7, p e1009460 (2021)
PLoS Genetics, Vol 17, Iss 7, p e1009460 (2021)
Visual perception of the environment is mediated by specialized photoreceptor (PR) neurons of the eye. Each PR expresses photosensitive opsins, which are activated by a particular wavelength of light. In most insects, the visual system comprises a pa