Výsledky vyhledávání - "Roula Said-Nahal"

Akademický článek

STAT1 deficiency underlies a proinflammatory imprint of naive CD4+ T cells in spondyloarthritis

Autor: Bilade Cherqaoui, Frédéric Crémazy, Marc Lauraine, Ghazal Shammas, Roula Said-Nahal, Hendrick Mambu Mambueni, Félicie Costantino, Marine Fourmont, Audrey Hulot, Henri-Jean Garchon, Simon Glatigny, Luiza M. Araujo, Maxime Breban

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionIn spondyloarthritis (SpA), an increased type 3 immune response, including T helper cells (Th) 17 excess, is observed in both human and SpA animal models, such as the HLA-B27/human β2-microglobulin transgenic rat (B27-rat).MethodsTo inve

Externí odkaz: https://doaj.org/article/4fea71dbadc045d08ad2b38023590273

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Akademický článek

Rheumatoid arthritis, as a clinical disease, but not rheumatoid arthritis-associated autoimmunity, is linked to cardiovascular events

Autor: Hélène Gouze, Philippe Aegerter, Roula Said-Nahal, Marie Zins, Marcel Goldberg, Guillaume Morelle, Georg Schett, Maxime Breban, Maria Antonietta D’Agostino

Publikováno v: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-8 (2022)

Abstract Background Rheumatoid arthritis (RA) is characterized by increased cardiovascular (CV) mortality. CV events are particularly high in patients with RA-specific autoimmunity, including rheumatoid factor (RF) and anti-citrullinated protein anti

Externí odkaz: https://doaj.org/article/8829ec91260b4ad59f7080ce81c3635f

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Akademický článek

What Have We Learned From Family-Based Studies About Spondyloarthritis?

Autor: Félicie Costantino, Hendrick Mambu Mambueni, Roula Said-Nahal, Henri-Jean Garchon, Maxime Breban

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Spondyloarthritis (SpA) is a chronic inflammatory disorder with a high familial aggregation, emphasizing the existence of genetic susceptibility factors. In the last decades, family-based studies have contributed to better understand the genetic back

Externí odkaz: https://doaj.org/article/ea1e5a4282e843c4b70f397438dd87a0

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Akademický článek

Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis.

Autor: Elena Zinovieva, Catherine Bourgain, Amir Kadi, Franck Letourneur, Brigitte Izac, Roula Said-Nahal, Nicolas Lebrun, Nicolas Cagnard, Agathe Vigier, Sébastien Jacques, Corinne Miceli-Richard, Henri-Jean Garchon, Simon Heath, Céline Charon, Delphine Bacq, Anne Boland, Diana Zelenika, Gilles Chiocchia, Maxime Breban

Publikováno v: PLoS Genetics, Vol 5, Iss 6, p e1000528 (2009)

Spondyloarthritis (SpA) is a chronic inflammatory disorder with a strong genetic predisposition dominated by the role of HLA-B27. However, the contribution of other genes to the disease susceptibility has been clearly demonstrated. We previously repo

Externí odkaz: https://doaj.org/article/f1df2c2babf746f0a8c0a50ec1aac57e

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Both Disease Activity and HLA-B27 Status Are Associated With Gut Microbiome Dysbiosis in Spondyloarthritis Patients

Autor: Magali Berland, Victoria Meslier, Samar Berreira Ibraim, Emmanuelle Le Chatelier, Nicolas Pons, Nicolas Maziers, Florence Thirion, Franck Gauthier, Florian Plaza Oñate, Jean‐Pierre Furet, Ariane Leboime, Roula Said‐Nahal, Florence Levenez, Nathalie Galleron, Benoît Quinquis, Philippe Langella, Stanislav Dusko Ehrlich, Maxime Breban

Publikováno v: Arthritis and Rheumatology (hoboken, N.j.)
Arthritis and Rheumatology (hoboken, N.j.), 2023, 75 (1), pp.41-52. ⟨10.1002/art.42289⟩

We gratefully acknowledge the kind contribution of Mrs. Nabila Yasmine Domingo-Saidji from the Clinical Research Unit of Paris Ile-de-France Ouest (URCPO), who supervised the administrative paperwork and helped us to manage ethical issues related to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5abad39ac59dd72b38f923046e5065a
https://pubmed.ncbi.nlm.nih.gov/35818337

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Targeted resequencing of the 13q13 spondyloarthritis-linked locus identifies a rare variant in FREM2 possibly associated with familial spondyloarthritis

Autor: Hendrick Mambu Mambueni, Christophe Hue, Aude Jobart-Malfait, Roula Said-Nahal, Hanane El Hafci, Hervé Petite, Christophe Nich, Maxime Breban, Félicie Costantino, Henri-Jean Garchon

Publikováno v: Joint bone spine. 89(6)

The strong heritability of spondyloarthritis remains poorly explained, despite several large-scale association studies. A recent linkage analysis identified a new region linked to SpA on 13q13. Here we searched for variants potentially explaining thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cdb4ec46c7b156aadfc660ee4fbe1b
https://pubmed.ncbi.nlm.nih.gov/35640836

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Rheumatoid arthritis, as a clinical disease, but not rheumatoid arthritis-associated autoimmunity, is linked to cardiovascular events

Autor: Maxime Breban, Helene Gouze, Georg Schett, Philippe Aegerter, Guillaume Morelle, Roula Said-Nahal, Maria Antonietta D'Agostino, Marie Zins, Marcel Goldberg

Publikováno v: Arthritis Research and Therapy
Arthritis Research and Therapy, 2022, 24 (1), pp.56. ⟨10.1186/s13075-022-02722-z⟩

Background Rheumatoid arthritis (RA) is characterized by increased cardiovascular (CV) mortality. CV events are particularly high in patients with RA-specific autoimmunity, including rheumatoid factor (RF) and anti-citrullinated protein antibodies (A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3865cfcfd277f7a351629d737b6004
http://hdl.handle.net/10807/198132

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La survenue brutale et inattendue d’événements stressants est suivie d’une augmentation d’activité de la spondyloarthrite : étude longitudinale en ligne sur deux ans

Autor: Maxime Breban, Clément Turbelin, Pierre-Yves Boëlle, Roula Said-Nahal, Thomas Hanslik, Guanguan Luo, Félicie Costantino, Solen Kernéis

Publikováno v: Revue du Rhumatisme
Revue du Rhumatisme, Elsevier, 2019, 86, pp.497-503. ⟨10.1016/j.rhum.2019.07.015⟩
Revue du Rhumatisme, 2019, 86 (5), pp.497-503. ⟨10.1016/j.rhum.2019.07.015⟩

International audience; ObjectifL’effet des facteurs environnementaux sur le cours de la spondyloarthrite (SpA) est encore mal caractérisé. Nous avons rapporté précédemment la possibilité que des poussées de la maladie soient déclenchées p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a82269b31581a9c2ec722b2a554be0
https://doi.org/10.1016/j.rhum.2019.07.015

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Radiographic sacroiliitis develops predictably over time in a cohort of familial spondyloarthritis followed longitudinally

Autor: Roula Said-Nahal, Maxime Breban, Nadine Zeboulon, Félicie Costantino

Publikováno v: Rheumatology. 56:811-817

Objectives Radiographic sacroiliitis is an important outcome in SpA and is considered a hallmark to ascertain the diagnosis of AS. The aim of the current study was to investigate factors associated with the presence of radiographic sacroiliitis at ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ae50d6815138ea273da3ebbcf52f78
https://doi.org/10.1093/rheumatology/kew496

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