In silico and in vitro characterization of the mycobacterial protein Ku to unravel its role in non-homologous end-joining DNA repair.

Autor: Baral J; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, West Bengal, India; School of Physics, University of Melbourne, Victoria, Australia; Department of Biochemistry and Pharmacology, University of Melbourne, Victoria, Australia; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Australia; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, The University of Melbourne, Melbourne, VIC 3010, Australia., Bhattacharje G; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, West Bengal, India., Dash S; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, West Bengal, India., Samanta D; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, West Bengal, India., Hinde E; School of Physics, University of Melbourne, Victoria, Australia. Electronic address: elizabeth.hinde@unimelb.edu.au., Rouiller I; Department of Biochemistry and Pharmacology, University of Melbourne, Victoria, Australia; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Australia; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, The University of Melbourne, Melbourne, VIC 3010, Australia. Electronic address: isabelle.rouiller@unimelb.edu.au., Das AK; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, West Bengal, India. Electronic address: amitk@bt.iitkgp.ac.in.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 1), pp. 134584. Date of Electronic Publication: 2024 Aug 08.

When the Trial Ends: The Case for Post-Trial Provisions in Clinical Psychedelic Research.

Autor: Jacobs E; Department of Psychiatry, University of Oxford, Oxford, UK.; Wellcome Centre for Ethics and Humanities, University of Oxford, Oxford, UK., Murphy-Beiner A; Department of Brain Sciences, Imperial College London, London, UK.; Department of Psychology, Royal Holloway University, London, UK., Rouiller I; Psychedelic Participant Advocacy Network (PsyPAN), London, UK., Nutt D; Department of Brain Sciences, Imperial College London, London, UK., Spriggs MJ; Department of Brain Sciences, Imperial College London, London, UK.

Publikováno v: Neuroethics [Neuroethics] 2024; Vol. 17 (1), pp. 3. Date of Electronic Publication: 2023 Nov 06.

MDSPACE: Extracting Continuous Conformational Landscapes from Cryo-EM Single Particle Datasets Using 3D-to-2D Flexible Fitting based on Molecular Dynamics Simulation.

Autor: Vuillemot R; IMPMC-UMR 7590 CNRS, Sorbonne Université, Muséum National d'Histoire Naturelle, Paris, France; Department of Biochemistry & Pharmacology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, Australia., Mirzaei A; IMPMC-UMR 7590 CNRS, Sorbonne Université, Muséum National d'Histoire Naturelle, Paris, France., Harastani M; IMPMC-UMR 7590 CNRS, Sorbonne Université, Muséum National d'Histoire Naturelle, Paris, France., Hamitouche I; IMPMC-UMR 7590 CNRS, Sorbonne Université, Muséum National d'Histoire Naturelle, Paris, France., Fréchin L; Centre for Integrative Biology, Department of Integrated Structural Biology, IGBMC-UMR 7104 CNRS, U964 Inserm, Université de Strasbourg, Strasbourg, France., Klaholz BP; Centre for Integrative Biology, Department of Integrated Structural Biology, IGBMC-UMR 7104 CNRS, U964 Inserm, Université de Strasbourg, Strasbourg, France., Miyashita O; RIKEN Center for Computational Science, Kobe, Japan., Tama F; RIKEN Center for Computational Science, Kobe, Japan; Institute of Transformative Biomolecules, Graduate School of Science, Nagoya University, Nagoya, Japan; Department of Physics, Graduate School of Science, Nagoya University, Nagoya, Japan., Rouiller I; Department of Biochemistry & Pharmacology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, Australia., Jonic S; IMPMC-UMR 7590 CNRS, Sorbonne Université, Muséum National d'Histoire Naturelle, Paris, France. Electronic address: slavica.jonic@upmc.fr.

Publikováno v: Journal of molecular biology [J Mol Biol] 2023 May 01; Vol. 435 (9), pp. 167951. Date of Electronic Publication: 2023 Jan 10.

In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor.

Autor: Mirzadeh A; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia., Kobakhidze G; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia., Vuillemot R; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.; IMPMC - UMR 7590, CNRS, Sorbonne Université, Muséum National d'Histoire Naturelle, Paris, France., Jonic S; IMPMC - UMR 7590, CNRS, Sorbonne Université, Muséum National d'Histoire Naturelle, Paris, France., Rouiller I; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia. isabelle.rouiller@unimelb.edu.au.

Publikováno v: BMC molecular and cell biology [BMC Mol Cell Biol] 2022 Sep 10; Vol. 23 (1), pp. 39. Date of Electronic Publication: 2022 Sep 10.

Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody.

Autor: Heydarchi B; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Fong DS; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Gao H; Department of Surgery, Duke University Medical Center, Durham, NC, USA., Salazar-Quiroz NA; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Edwards JM; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Gonelli CA; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Grimley S; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Aktepe TE; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Mackenzie C; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia., Wales WJ; Dairy Production Sciences, Victorian Department of Jobs, Precincts and Resources, Ellinbank, VIC, Australia; Centre for Agricultural Innovation, School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, VIC 3010, Australia., van Gils MJ; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105AZ Amsterdam, the Netherlands., Cupo A; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA., Rouiller I; Department of Biochemistry & Pharmacology, The University of Melbourne, Melbourne, VIC 3010, Australia; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia; Australian Research Council Centre for Cryo-Electron Microscopy of Membrane Proteins, Parkville, VIC, Australia., Gooley PR; Department of Biochemistry & Pharmacology, The University of Melbourne, Melbourne, VIC 3010, Australia; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia., Moore JP; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA., Sanders RW; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105AZ Amsterdam, the Netherlands; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA., Montefiori D; Department of Surgery, Duke University Medical Center, Durham, NC, USA., Sethi A; Department of Biochemistry & Pharmacology, The University of Melbourne, Melbourne, VIC 3010, Australia; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia., Purcell DFJ; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection Immunity, University of Melbourne, Melbourne, VIC 3000, Australia. Electronic address: dfjp@unimelb.edu.au.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2022 May 17; Vol. 3 (5), pp. 100635.