Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rouchelle Sriranjan"'
Autor:
Elizabeth P.V. Le, Mark Y.Z. Wong, Leonardo Rundo, Jason M. Tarkin, Nicholas R. Evans, Jonathan R. Weir-McCall, Mohammed M. Chowdhury, Patrick A. Coughlin, Holly Pavey, Fulvio Zaccagna, Chris Wall, Rouchelle Sriranjan, Andrej Corovic, Yuan Huang, Elizabeth A. Warburton, Evis Sala, Michael Roberts, Carola-Bibiane Schönlieb, James H.F. Rudd
Publikováno v:
European Journal of Radiology Open, Vol 13, Iss , Pp 100594- (2024)
Purpose: To assess radiomics and deep learning (DL) methods in identifying symptomatic Carotid Artery Disease (CAD) from carotid CT angiography (CTA) images. We further compare the performance of these novel methods to the conventional calcium score.
Externí odkaz:
https://doaj.org/article/5f3bf2f517c440329ea8eac866760768
Autor:
Akimichi Inaba, Zewen Kelvin Tuong, Tian X. Zhao, Andrew P. Stewart, Rebeccah Mathews, Lucy Truman, Rouchelle Sriranjan, Jane Kennet, Kourosh Saeb-Parsy, Linda Wicker, Frank Waldron-Lynch, Joseph Cheriyan, John A. Todd, Ziad Mallat, Menna R. Clatworthy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Dysfunction of interleukin-10 producing regulatory B cells has been associated with the pathogenesis of autoimmune diseases, but whether regulatory B cells can be therapeutically induced in humans is currently unknown. Here we demonstrate th
Externí odkaz:
https://doaj.org/article/733547fe76a040a4be8f3da2878d86c9
Autor:
Joseph Cheriyan, Simon Bond, Stephen P Hoole, James H F Rudd, Jason Tarkin, Evangelia Vamvaka, Joanna Helmy, Annette Hubsch, Tian Xiao Zhao, Ziad Mallat, Rouchelle Sriranjan, Paul Cacciottolo, Navazh Jalaludeen, Philip Knott, Samantha Buckenham, Victoria Warnes, Nick Bird, Heok Cheow, Heike Templin
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Introduction Inflammation plays a critical role in the pathogenesis of atherosclerosis, the leading cause of ischaemic heart disease (IHD). Studies in preclinical models have demonstrated that an increase in regulatory T cells (Tregs), which have a p
Externí odkaz:
https://doaj.org/article/9a57033968fa45b2aaa74f90d282ea7d
Autor:
Elizabeth P. V. Le, Leonardo Rundo, Jason M. Tarkin, Nicholas R. Evans, Mohammed M. Chowdhury, Patrick A. Coughlin, Holly Pavey, Chris Wall, Fulvio Zaccagna, Ferdia A. Gallagher, Yuan Huang, Rouchelle Sriranjan, Anthony Le, Jonathan R. Weir-McCall, Michael Roberts, Fiona J. Gilbert, Elizabeth A. Warburton, Carola-Bibiane Schönlieb, Evis Sala, James H. F. Rudd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Radiomics, quantitative feature extraction from radiological images, can improve disease diagnosis and prognostication. However, radiomic features are susceptible to image acquisition and segmentation variability. Ideally, only features robu
Externí odkaz:
https://doaj.org/article/3c38d77b56a846ac9f44b3d1df1785f4
Autor:
Simon Bond, Joseph Cheriyan, Jean-Sébastien Silvestre, Brian Y.H. Lam, Yanyi Sun, James H.F. Rudd, Yuning Lu, Marcella Ma, Ziad Mallat, Meritxell Nus, James Harrison, Rouchelle Sriranjan, Andrew S. Sage, Xian Yu, Stephen A. Newland, Tian X. Zhao, Xiang Cheng
Publikováno v:
Journal of the American College of Cardiology. 78:1127-1142
BACKGROUND: Innate lymphoid cells type 2 (ILC2s) play critical homeostatic functions in peripheral tissues. ILC2s reside in perivascular niches and limit atherosclerosis development. OBJECTIVES: ILC2s also reside in the pericardium but their role in
Autor:
Rouchelle, Sriranjan, Tian Xiao, Zhao, Jason, Tarkin, Annette, Hubsch, Joanna, Helmy, Evangelia, Vamvaka, Navazh, Jalaludeen, Simon, Bond, Stephen P, Hoole, Philip, Knott, Samantha, Buckenham, Victoria, Warnes, Nick, Bird, Heok, Cheow, Heike, Templin, Paul, Cacciottolo, James H F, Rudd, Ziad, Mallat, Joseph, Cheriyan
Publikováno v:
BMJ open. 12(10)
Inflammation plays a critical role in the pathogenesis of atherosclerosis, the leading cause of ischaemic heart disease (IHD). Studies in preclinical models have demonstrated that an increase in regulatory T cells (Tregs), which have a potent immune
Autor:
Elizabeth Le, Leonardo Rundo, Jason Tarkin, Nicholas Evans, Mohammed Chowdhury, Patrick Coughlin, Holly Pavey, Chris Wall, Fulvio Zaccagna, Ferdia Gallagher, Yuan Huang, Rouchelle Sriranjan, Anthony Le, Jonathan Weir-McCall, Michael Roberts, Fiona Gilbert, Elizabeth Warburton, Carola-Bibiane Schönlieb, Evis Sala, James Rudd
Publikováno v:
Imaging.
Autor:
Rouchelle Sriranjan, Tian Xiao Zhao, Jason Tarkin, Annette Hubsch, Joanna Helmy, Evangelia Vamvaka, Navazh Jalaludeen, Simon Bond, Stephen P Hoole, Philip Knott, Samantha Buckenham, Victoria Warnes, Nick Bird, Heok Cheow, Heike Templin, Paul Cacciottolo, James H F Rudd, Ziad Mallat, Joseph Cheriyan
Publikováno v:
BMJ Open. 12:e062602
IntroductionInflammation plays a critical role in the pathogenesis of atherosclerosis, the leading cause of ischaemic heart disease (IHD). Studies in preclinical models have demonstrated that an increase in regulatory T cells (Tregs), which have a po
Autor:
Rouchelle Sriranjan, Michael S. Roberts, Fulvio Zaccagna, Nicholas R. Evans, Carola-Bibiane Schönlieb, Elizabeth A. Warburton, Anthony Le, Leonardo Rundo, Ferdia A. Gallagher, Yuan Huang, James H.F. Rudd, Patrick A. Coughlin, Mohammed M. Chowdhury, Jason M. Tarkin, Elizabeth P.V. Le, Fiona J. Gilbert, Holly Pavey, Jonathan R. Weir-McCall, Christopher Wall, Evis Sala
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Radiomics, quantitative feature extraction from radiological images, can improve disease diagnosis and prognostication. However, radiomic features are susceptible to image acquisition and segmentation variability. Ideally, only features robust to the
Autor:
Evangelia Vamvaka, S.P Hoole, Michael S. Kostapanos, Ziad Mallat, S.P Bond, James H. F. Rudd, Alain Tedgui, Yuning Lu, Joanna Helmy, Joseph Cheriyan, Rouchelle Sriranjan, Fotini Kaloyirou, Annette Hubsch, D Klatzmann, Tian X. Zhao
Publikováno v:
European Heart Journal. 41
Background Regulatory T lymphocytes (Tregs) are critical for immune homeostasis. Pre-clinical models have demonstrated that Tregs can modulate post-ischaemic immune responses and promote myocardial healing. Patients with ischaemic heart disease (IHD)