Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Rouben Aroutiounian"'
Changes in Telomere Length in Leukocytes and Leukemic Cells after Ultrashort Electron Beam Radiation
Autor:
Tigran Harutyunyan, Anzhela Sargsyan, Lily Kalashyan, Hovhannes Igityan, Bagrat Grigoryan, Hakob Davtyan, Rouben Aroutiounian, Thomas Liehr, Galina Hovhannisyan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6709 (2024)
Application of laser-generated electron beams in radiotherapy is a recent development. Accordingly, mechanisms of biological response to radiation damage need to be investigated. In this study, telomere length (TL) as endpoint of genetic damage was a
Externí odkaz:
https://doaj.org/article/ab120ac5ed014764a3a04551e414db6b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14163 (2023)
Cell-free DNA (cfDNA) in human blood serum, urine, and other body fluids recently became a commonly used diagnostic marker associated with various pathologies. This is because cfDNA enables a much higher sensitivity than standard biochemical paramete
Externí odkaz:
https://doaj.org/article/8fff236edbf0467a90fb2cf2b6978bc3
Autor:
Alla Khosrovyan, Rima Avalyan, Anahit Atoyants, Evelina Aghajanyan, Lusine Hambaryan, Rouben Aroutiounian, Bardukh Gabrielyan
Publikováno v:
Water, Vol 15, Iss 13, p 2500 (2023)
Harmful algal blooms (HABs) are overgrowths of toxic strains of algae (diatoms, green) and cyanobacteria (blue-green algae). While occurring naturally, human-induced environmental changes have resulted in more frequent occurrences of such blooms worl
Externí odkaz:
https://doaj.org/article/d694f53e673e427a9bc4a5eb01fcf674
Autor:
Anna Nebish, Javier Tello, Yolanda Ferradás, Rouben Aroutiounian, José Miguel Martínez-Zapater, Javier Ibáñez
Publikováno v:
OENO One, Vol 55, Iss 4 (2021)
The South Caucasus is recognised as the primary Vitis vinifera L. (grapevine) domestication centre and has a high diversity of wild and cultivated grapevines. Archaeological findings indicate that winemaking activities have existed in Armenia for mor
Externí odkaz:
https://doaj.org/article/4930525beb6b49b6b7cdb8e284db8f41
Autor:
Tigran Harutyunyan, Galina Hovhannisyan, Anzhela Sargsyan, Bagrat Grigoryan, Ahmed H. Al-Rikabi, Anja Weise, Thomas Liehr, Rouben Aroutiounian
Publikováno v:
Molecular Cytogenetics, Vol 12, Iss 1, Pp 1-6 (2019)
Abstract Background Environmental risk factors have been shown to alter DNA copy number variations (CNVs). Recently, CNVs have been described to arise after low-dose ionizing radiation in vitro and in vivo. Development of cost- and size-effective las
Externí odkaz:
https://doaj.org/article/c9348de95ca54eca9c9c47b7c2bfdf81
Autor:
Gohar Tsakanova, Nelly Babayan, Elena Karalova, Lina Hakobyan, Liana Abroyan, Aida Avetisyan, Hranush Avagyan, Sona Hakobyan, Arpine Poghosyan, Bagrat Baghdasaryan, Elina Arakelova, Violetta Ayvazyan, Lusine Matevosyan, Arpine Navasardyan, Hakob Davtyan, Lilit Apresyan, Arsham Yeremyan, Rouben Aroutiounian, Andreyan N. Osipov, Bagrat Grigoryan, Zaven Karalyan
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11525 (2021)
The development of new laser-driven electron linear accelerators, providing unique ultrashort pulsed electron beams (UPEBs) with low repetition rates, opens new opportunities for radiotherapy and new fronts for radiobiological research in general. Co
Externí odkaz:
https://doaj.org/article/ea8d7c800bd741c3a6c5637ba2e61989
Autor:
Nelly Babayan, Natalia Vorobyeva, Bagrat Grigoryan, Anna Grekhova, Margarita Pustovalova, Sofya Rodneva, Yuriy Fedotov, Gohar Tsakanova, Rouben Aroutiounian, Andreyan Osipov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9488 (2020)
Laser-driven accelerators allow to generate ultrashort (from femto- to picoseconds) high peak dose-rate (up to tens of GGy/s) accelerated particle beams. However, the radiobiological effects of ultrashort pulsed irradiation are still poorly studied.
Externí odkaz:
https://doaj.org/article/555b6fb94339423ebb5efe5a43204077
Autor:
Tigran Harutyunyan, Ahmed Al-Rikabi, Anzhela Sargsyan, Galina Hovhannisyan, Rouben Aroutiounian, Thomas Liehr
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7690 (2020)
Translocation of mtDNA in the nuclear genome is an ongoing process that contributes to the development of pathological conditions in humans. However, the causal factors of this biological phenomenon in human cells are poorly studied. Here we analyzed
Externí odkaz:
https://doaj.org/article/72c59cc768bf45eb8ad560e2cbac62a2
Autor:
Nelly Babayan, Bagrat Grigoryan, Lusine Khondkaryan, Gohar Tadevosyan, Natalya Sarkisyan, Ruzanna Grigoryan, Lilit Apresyan, Rouben Aroutiounian, Natalia Vorobyeva, Margarita Pustovalova, Anna Grekhova, Andreyan N. Osipov
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5140 (2019)
Rapidly evolving laser technologies have led to the development of laser-generated particle accelerators as an alternative to conventional facilities. However, the radiobiological characteristics need to be determined to enhance their applications in
Externí odkaz:
https://doaj.org/article/a51a61b495e5489f8e4bcf2cf2f70ffe
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4723 (2019)
DNA copy number variation (CNV) occurs due to deletion or duplication of DNA segments resulting in a different number of copies of a specific DNA-stretch on homologous chromosomes. Implications of CNVs in evolution and development of different diseas
Externí odkaz:
https://doaj.org/article/e530e84429ca4e57b7a781eb0242ceab