Etude du rôle de la balance HAT/HDAC dans les phénomènes de neurodégénérescence Mise en évidence du rôle neuroprotecteur de CBP et des effets thérapeutiques des inhibiteurs de HDAC sur un modèle murin de sclérose latérale amyotrophique

Autor: Rouaux, Caroline Boutillier, Anne-Laurence.

Publikováno v: Thèse électronique de l'Université Louis Pasteur de Strasbourg.

Thèse doctorat : Sciences du vivant. Aspects Moléculaires et Cellulaires de la Biologie : Strasbourg 1 : 2006.
Thèse soutenue sur un ensemble de travaux. Titre provenant de l'écran-titre. Bibliogr. 34 p.

Externí odkaz: http://eprints-scd-ulp.u-strasbg.fr:8080/908/01/ROUAUX_Caroline_2006.pdf

Nogo Receptor Antagonizes p75NTR-Dependent Motor Neuron Death

Autor: Dupuis, Luc, Pehar, Mariana, Cassina, Patricia, Rene, Frédérique, Castellanos, Raquel, Rouaux, Caroline, Gandelman, Mandi, Dimou, Leda, Schwab, Martin E., Loeffler, Jean-Philippe, Barbeito, Luis, de Aguilar, Jose-Luis Gonzalez

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2008 Jan . 105(2), 740-745.

Externí odkaz: https://www.jstor.org/stable/25451160

Absence of Subcerebral Projection Neurons Is Beneficial in a Mouse Model of Amyotrophic Lateral Sclerosis

Autor: Burg, Thibaut, Bichara, Charlotte, Scekic‐Zahirovic, Jelena, Fischer, Mathieu, Stuart‐Lopez, Geoffrey, Brunet, Aurore, Lefebvre, François, Cordero‐Erausquin, Matilde, Rouaux, Caroline

Publikováno v: Annals of Neurology
Annals of Neurology, Wiley, 2020, 88 (4), pp.688-702. ⟨10.1002/ana.25833⟩

Objective Recent studies carried out on amyotrophic lateral sclerosis patients suggest that the disease might initiate in the motor cortex and spread to its targets along the corticofugal tracts. In this study, we aimed to test the corticofugal hypot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::03a527a9759c1a196b26a03a976a17c0
https://hal.archives-ouvertes.fr/hal-03064682

Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis

Autor: Brunet, Aurore, Stuart-Lopez, Geoffrey, Burg, Thibaut, Scekic-Zahirovic, Jelena, Rouaux, Caroline

Publikováno v: Frontiers in Neuroscience
Frontiers in Neuroscience, Frontiers, 2020, 14, pp.363. ⟨10.3389/fnins.2020.00363⟩
Frontiers in Neuroscience, 2020, 14, pp.363. ⟨10.3389/fnins.2020.00363⟩
Frontiers in Neuroscience, Vol 14 (2020)

International audience; Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects selected cortical and spinal neuronal populations, leading to progressive paralysis and death. A growing body of evidences suggests th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::790ee0150c619f984ae67933ac52d194
http://europepmc.org/articles/PMC7201269

Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis

Autor: El Oussini, Hajer, Scekic-Zahirovic, Jelena, Vercruysse, Pauline, Marques, Christine, Dirrig-Grosch, Sylvie, Dieterlé, Stéphane, Picchiarelli, Gina, Sinniger, Jérôme, Rouaux, Caroline, Dupuis, Luc

Publikováno v: Annals of Neurology
Annals of Neurology, 2017, 82 (3), pp.444-456. ⟨10.1002/ana.25030⟩
Annals of Neurology, Wiley, 2017, 82 (3), pp.444-456. ⟨10.1002/ana.25030⟩

International audience; Objective: Spasticity occurs in a wide range of neurological diseases, including neurodegenerative diseases, after trauma, and after stroke, and is characterized by increased reflexes leading to muscle hypertonia. Spasticity i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a8eba411f3937d12f7660c75c8c43e75
https://www.hal.inserm.fr/inserm-03375232/document