Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Rou-Gang Xie"'
Autor:
Lamei Li, Yuanying Liu, Wenchao Hu, Jing Yang, Suibin Ma, Zhicheng Tian, Zixuan Cao, Kunqing Pan, Ming Jiang, Xia Liu, Shengxi Wu, Ceng Luo, Rou-Gang Xie
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The C-C motif chemokine ligand 2 (CCL2) has been implicated in chronic pain, but its exact mechanism of peripheral sensitization is unknown. In this study, we aimed to clarify the mechanism of CCL2 regulation of ion channels. Our behavioral experimen
Externí odkaz:
https://doaj.org/article/b35b650aa1a74e45b0612e42e3995b11
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionBrachial plexus avulsion (BPA) injury develops frequent and intense neuropathic pain, involving in both peripheral and central nervous systems. The incidence of anxiety or depression caused by BPA-induced neuropathic pain is high, but the
Externí odkaz:
https://doaj.org/article/dd01bf95bb0644ea8ff369bf5d107b52
Autor:
Rou-Gang Xie, Wen-Guang Chu, Da-Lu Liu, Xu Wang, Sui-Bin Ma, Fei Wang, Fu-Dong Wang, Zhen Lin, Wen-Bin Wu, Na Lu, Ying-Ying Liu, Wen-Juan Han, Hui Zhang, Zhan-Tao Bai, San-Jue Hu, Hui-Ren Tao, Thomas Kuner, Xu Zhang, Rohini Kuner, Sheng-Xi Wu, Ceng Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
Postsynaptic NMDARs at spinal synapses are required for postsynaptic long-term potentiation and chronic pain. Here, the authors show that also presynaptic NMDARs in spinal nociceptor terminals modulate synaptic transmission in a nociceptive tone-depe
Externí odkaz:
https://doaj.org/article/28719986d3e5455c8f1c09bc8c42cfe6
Autor:
Gang Chen, Rou-Gang Xie, Yong-Jing Gao, Zhen-Zhong Xu, Lin-Xia Zhao, Sangsu Bang, Temugin Berta, Chul-Kyu Park, Mark Lay, Wei Chen, Ru-Rong Ji
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The cellular mechanisms underlying acute pain transitions to chronic pain are poorly understood. Here the authors show that the scaffolding protein β-arrestin 2 contributes to these processes via desensitization of NMDA receptors in spinal neurons.
Externí odkaz:
https://doaj.org/article/d71d3fc96fe3477b80fc968a12f53cb5
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 161 (2018)
Sensory neuron types have been distinguished by distinct morphological and transcriptional characteristics. Excitability is the most fundamental functional feature of neurons. Mathematical models described by Hodgkin have revealed three types of neur
Externí odkaz:
https://doaj.org/article/d33242c397a6499fba9eabaa7b629260
Autor:
Ceng Luo, Vijayan Gangadharan, Kiran Kumar Bali, Rou-Gang Xie, Nitin Agarwal, Martina Kurejova, Anke Tappe-Theodor, Irmgard Tegeder, Susanne Feil, Gary Lewin, Erika Polgar, Andrew J Todd, Jens Schlossmann, Franz Hofmann, Da-Lu Liu, San-Jue Hu, Robert Feil, Thomas Kuner, Rohini Kuner
Publikováno v:
PLoS Biology, Vol 10, Iss 3, p e1001283 (2012)
Synaptic long-term potentiation (LTP) at spinal neurons directly communicating pain-specific inputs from the periphery to the brain has been proposed to serve as a trigger for pain hypersensitivity in pathological states. Previous studies have functi
Externí odkaz:
https://doaj.org/article/d9f9d1624edd4308a0d8e0d8ab9c4916
Autor:
Rou-Gang Xie, Da-Wei Zheng, Jun-Ling Xing, Xu-Jie Zhang, Ying Song, Ya-Bin Xie, Fang Kuang, Hui Dong, Si-Wei You, Hui Xu, San-Jue Hu
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18681 (2011)
In addition to a fast activating and immediately inactivating inward sodium current, many types of excitable cells possess a noninactivating or slowly inactivating component: the persistent sodium current (I(NaP)). The I(NaP) is found in normal prima
Externí odkaz:
https://doaj.org/article/11f4c6a043254f6d908d450476aee348
Autor:
Lamei Li, Yuanying Liu, Wenchao Hu, Jing Yang, Suibin Ma, Zhicheng Tian, Zixuan Cao, Kunqing Pan, Ming Jiang, Xia Liu, Shengxi Wu, Ceng Luo, Rou-Gang Xie
Publikováno v:
Frontiers in Molecular Neuroscience; 2023, p1-14, 14p
Autor:
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Ruilong Xia, Ting Wen, Wei Xia, Ran Qian, Fengting Zhu, Yuanying Liu, Zhicheng Tian, Lamei Li, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou-Gang Xie, Changgeng Peng
Neuropathic pain affects 7-10% of the global population, and one of its characteristics is sensitization of somatosensory nervous system. Altered expression of ion channels and receptors has been found to be involved in neuronal hyperexcitability aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be55e746b8419157221e7e13ace2fa17
https://doi.org/10.1101/2022.11.05.22281929
https://doi.org/10.1101/2022.11.05.22281929
Autor:
Yilin Hou, Jiqian Zhao, Runkang Xuan, Dingding Yang, Wenting Wang, Shengxi Wu, Rou-Gang Xie, Xufeng Liu, Yazhou Wang, Huiming Mo, Mengmeng Wang, Lirong Liang
Publikováno v:
Biochemical and Biophysical Research Communications. 550:22-29
Autism spectrum disorders (ASD) are a group of neurological disorders which affect approximately 1% of children around the world. Social dysfunction is one of the two core syndromes of ASD, and still lacks effective treatment. Transcranial magnetic s